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Zhishang Chemical

DL-Limonene CAS 138-86-3

Molecular Formula: C10H16

Formula Weight: 136.23

ZSpharmac: DL-Limonene Supplement

Product Name: DL-Limonene
CAS No: 138-86-3
Purity: 99%

Basic Info

Product Name:DL-Limonene
Other Names:Dipentene
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless to Pale Yellow Liquid
EINECS No.:205-341-0
Storage:Store Below +30°C.
Provide:DL-Limonene MSDS;
DL-Limonene COA

What is DL-Limonene?

DL-Limonene, taxonomic name 1-methyl-4-isopropylcyclohexene, molecular formula C10H16, molecular weight 136.23, is a monocyclic monoterpene mainly present in orange peel necessary oil. It is an anemic to light yellow oily liquid at space temperature, with a specific lemon-like aroma, insoluble in water, and easily soluble in natural solvents such as ethanol. DL-Limonene can be automatically oxidized to oxidized monocyclic monoterpenes, such as carvacrol, limonene-1,2- oxide, and so on, under the problem of light direct exposure and air contact, as well as has very active chemical residential properties. DL-Limonene has two configurations, D as well as L, mostly in the form of D-isomer. D-Limonene generally exists in necessary oils such as orange peel oil, grapefruit oil, lemon oil, and so on, specifically in

Orange peel off oil is rich in material (more than 90%). D-Limonene can significantly inhibit the activity of Gram-negative and favorable germs and fungi. Limonene has a variety of resources, simple removal as well as high sensible value, and is currently a hot spot in residential study. A multitude of research study outcomes show that limonene has good expectorant and also antiasthmatic, antioxidant, anti-inflammatory, anti-tumor, dissolving gallstones, as well as anti-bacterial effects.One of the disadvantages of most essential oils as natural preservatives is their potential toxicity to humans, but the edible safety of limonene has been recognized internationally, and its toxicity has been recognized as generally recognized as safe by the American Flavours and Extracts Manufacturers Association (Generally Recognized as Safe). Recognized as Safe, GRAS), the International Association of Daily Flavor and Fragrances does not limit the amount of D-limonene, and the Food and Agriculture Organization of the United Nations and the World Health Organization do not set the Acceptable Daily Intake (ADI) of D-limonene. Special provisions and approved by the U.S. Food and Drug Administration. It has been widely used in food additives, medicine and health care, daily chemical products, pest control, etc. At present, its good antibacterial effect in the field of food preservation and storage has attracted more and more attention from researchers. In recent years, plant essential oils have gradually become a new type of bactericidal additive. Low concentrations of essential oils can inhibit most food spoilage bacteria and pathogenic bacteria, such as Escherichia coli O157: H7, Salmonella and waxy bacteria. Bacillus cereus, etc., while avoiding the shortcomings of conventional antibacterial preservation techniques. With the deepening of research, the antibacterial properties of various essential oils have been applied in many fields, and the most common use methods are direct contact and fumigation. DL-Limonene is one of the components of plant essential oils extracted from orange peel or orange peel. It has the natural antibacterial effect of plant essential oils, has a good inhibitory effect on common decay-causing bacteria, and has broad application prospects in food preservation.

DL-Limonene Properties:

Melting point -84–104 °C
Boiling point 170-180 °C (lit.)
density 0.86 g/mL at 20 °C (lit.)
vapor density 4.7 (vs air)
vapor pressure <3 mm Hg ( 14.4 °C)
refractive index n20/D 1.473(lit.)
Fp 119 °F
storage temp. Store below +30°C.
form Liquid
color Clear colorless to pale yellow
OdorPleasant, pine-like; lemon-like.
Odor Threshold0.038ppm
explosive limit0.7-6.1%, 150°F
Water Solubility <1 g/100mL


DL-Limonene Uses

  1. DL-Limonene is made use of as a basic material for synthetic rubber, perfume, as well as likewise as a solvent.
  2. DL-Limonene is frequently utilized in its right-handed kind. It can be used as the raw product for the prep work of man-made orange blossom, pleasant blossom, lemon and also bergamot oil. It can additionally be used as a fresh top scent for cosmetics, soaps as well as daily chemical fragrances, in perfume, floral, jasmine, lavender, and want, aldehyde, woody, fruity or fragile. are suitable. As a modifier in edible flavors, it is used in solutions such as white lemon, fruity and spicy flavors.
  3. DL-Limonene is made use of as enamel, Japanese lacquer and various oleoresins, material waxes, metal driers as well as solvents; used in the manufacture of synthetic material and synthetic rubber; made use of for mixing orange blossom significance, citrus oil significance, and so on; A substitute for lemon vital oils. Limonene is directional oxidized to develop carvone; in the visibility of inorganic acid, limonene is contributed to water to create α-terpineol and hydrated terpene diol; hydrogenated under the activity of platinum or chromocatalyst to develop para-alkane, and also dehydrogenation generates para-umbrine Flower hydrocarbons. Additionally used as oil dispersant, rubber additive, wetting representative, and so on.
  4. DL-Limonene is used as a solvent and also for fragrance synthesis and pesticide production.

What is The Effect of DL-Limonene

DL-Limonene is a plant vital oil, which has a relatively apparent inhibitory result on common rot-causing germs that create meat spoilage, so it has wide application leads in the field of preservative conservation, such as hindering Staphylococcus aureus, Aspergillus niger, Escherichia coli, etc wasting of food. DL-Limonene was emulsified as well as contributed to orange juice to explore the preservation effect of limonene. When the enhancement amount of limonene was above 0.50 g/L, an extra apparent impact of preservation was gotten. The complete variety of microorganisms, pH adjustment and also sensory quality in orange juice were significantly better than those of the empty control throughout the speculative exploration process. The strawberries were soaked in the DL-Limonene compound option for 3 min. The examination results showed that, compared with the blank, each therapy can dramatically decrease the decrease of VC, titratable acid and also soluble solid material in strawberry fruit, prevent the water loss and also rot of strawberry, and improve the efficiency of strawberry fruit. Its storability.

DL-Limonene is a risk-free as well as non-toxic anti-bacterial compound. A large quantity of limonene gathers on the surface of bacteria, which causes a huge reduction in the material of unsaturated fatty acids in the membrane, alters the composition of the membrane or destroys its integrity, as well as lowers the proton power. accomplish bacteriostatic impact. Taking microorganisms, fungis and mold and mildews as study objects, the antibacterial buildings of pomelo peel crucial oil were examined. Research studies have actually revealed that pomelo peel vital oil has apparent inhibitory effect on numerous microbes, and also the antibacterial result slowly raises with the rise of pomelo peel essential oil focus.

The oxidative damages brought on by free radicals is associated with the event and development of cancer to a specific degree, as well as the capability of anti-oxidative damage is positively related to the prevention of cancer cells to a large extent, as well as the crucial oil essence abundant in D-limonene has excellent anti-oxidative residential or commercial properties and also is secure. Some literary works researches have actually found that kumquat essential oil abundant in D-limonene has great lightening beta-carotene, antioxidant capability, DPPH cost-free radical scavenging capability, as well as can supplement particular anti-oxidants to the body to safeguard the body from oxidative damage.

Swelling is closely pertaining to cancer. For instance, there is an intermediary particle between inflammatory response and cancer cells, nuclear transcription factor-κβ, as well as pro-inflammatory cytokines (such as tumor necrosis aspect TNF-α and also interleukin IL-6) in cancer cells. The initiation as well as developmental stages play an important role. Disrupting TNF-α or IL-6 signaling by hindering the activity of NF-κβ can efficiently hinder the incident of cancer cells. In this procedure, D-limonene can avoid swelling and also cancer cells by inhibiting the NF-κβ signaling path.

It has actually been reported in the literary works that limonene can act on little molecular G proteins connected to cell growth, prevent its prenylation as well as boost the activity and manufacturing of possible growth inhibitor TGFβ. Bust cancer cells, skin cancer cells, lymphoma, and so on have apparent preventative and also healing impacts. D-Limonene can act on the mucous membrane of the respiratory system system, advertise the boost of the secretion of the mucous membrane layer of the respiratory system tract, deteriorate the spontaneous task of bronchial smooth muscular tissue, eliminate bronchospasm, thereby assisting in the discharging of sputum, getting rid of phlegm and salivation, minimizing or subduing the impact of coughing and bronchial asthma; The sphincter kicks back to remove the stones, thereby reducing the excitement of the gallbladder mucosa, minimizing the generation of gallstones, as well as improving the client’s figure, which can not only accomplish the objective of healing, yet additionally stop the reappearance of stones. Limonene pills sold on the marketplace are suitable for the treatment of cholecystitis, cholangitis, gallstones, postoperative biliary syndrome and also acid indigestion. Some researches have located that D-limonene has a much better as well as much safer result on liquifying recurring rocks. Cholesterol comes from the biosynthesis of hepatocytes, and also a mixture consisting of 97% D-limonene is administered through gallbladder water drainage, which might prevent cholesterol synthesis, effectively clear gallbladder and also wetness, as well as liquify rocks. No postoperative symptoms were reported.

Efficacy of DL-Limonene on Various Skin Problems

DL-Limonene, a cyclic monoterpene, is the main aromatic compound in citrus essential oils, best known for its powerful purifying power, and studies have shown that it has numerous health benefits. In addition to being present in citrus essential oils, it is also one of the ingredients of black pepper, peppermint, and dill, giving us a strong orange scent and a common ingredient in countless cleaning and beauty products.

DL-Limonene is widely discussed and researched for its purifying properties. Some studies have examined its effectiveness as a surface cleaner. To take advantage of limonene’s powerful surface-cleaning properties, add a few drops of lemon, wild orange, lime, or other citrus essential oils to your homemade all-purpose cleaner, and add it to a glass spray bottle filled with water and a dash of white vinegar. You can also add a few drops of the above essential oils to your next laundry, or use them directly to remove stains from clothes, carpets, or furniture.

DL-Limonene has many different health benefits, and another study found that limonene helps feel smooth and fresh. Add 1-2 drops of lemon, tangerine, lime or grapefruit essential oils to give you a little change and boost your health with citrus essential oils.

The cleaning and purifying properties of limonene can be used not only in the bathroom and kitchen, but also on the teeth. Clinical studies have shown that, combined with the correct brushing habits, toothpaste containing limonene can whiten teeth and wash away dirt. Another study showed that limonene can make teeth look clean and healthy. Try adding a drop of lime or lemon essential oil to your toothpaste for an extra cleanser.

Citrus essential oils are basically associated with cleaning products because of their high concentration of limonene, and we also know that they have a refreshing and energizing aroma. In addition, there are many more uses, which can be used in the home environment and the health of the family.

D-Limonene is a monoterpene derived from orange peel, widely used in perfumes, soaps, detergents, and food. Another study confirmed that d-limonene can prevent a variety of cancers, especially breast cancer, prostate cancer and colon cancer.

Recently, French scholar Patrizia A. d’Alessio et al. analyzed the effect of d-limonene on skin diseases, emphasizing the anti-aging effect.

1. D-Limonene significantly improves inflammation and promotes wound healing

2. D-Limonene is effective in treating psoriasis and has moisturizing properties

3. D-Limonene can inhibit the formation of endothelial cells of new blood vessels

The researchers were surprised to find that when d-limonene promoted wound healing, there was a corresponding reduction in angiogenesis. This finding was further confirmed by an in vitro human umbilical vein endothelial cell model.

4. D-Limonene May Prevent Skin Cancer

Studies have shown that d-limonene can reduce tumor burden, and monoterpenes are associated with increased apoptosis, inhibition of oxidative stress, and Ras signaling.

5. D-Limonene Can Effectively Improve Wrinkles

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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