A Corsodyl Chlorhexidine Digluconate is prepared from the following basic materials: 5.5 g of polysorbate 80, 1.2 g of original metronidazole powder, 220 g of ethanol, 2.0 g of banana essence, 40 g of pepper mint water, and also 0.7 g of sodium saccharin, lemon yellow pigment 0.025 g, glycerin 315g, polyethylene glycol 400 is 275g, chlorhexidine gluconate (mass portion is 5%) 125g, cleansed water is appropriate. The preparation method of the chlorhexidine gluconate compound gargle comprises the complying with steps:
A, obtain polysorbate 80, the former powder of metronidazole and include container An and stir, under the problem that stirring speed is 60 rev/min, continue mixing after 20 mins and get ethanol as well as include 5 times, the initial 4 times 40g each time, 60g for the fifth time, include banana essence as well as mint water to Chemicalbook as well as mix for 20 mins under the condition that the stirring speed is 60 rev/min to acquire material liquid A;
B, sodium saccharin is liquified in container B with 50ml purified water to get feed service B;
c, tartrazine is dissolved in container C with 50ml cleansed water to obtain feed solution C;
D, in container D, add 3700ml purified water, add glycerol, polyethylene glycol 400 successively while stirring under the condition that stirring speed is 60 rev/min, then add the chlorhexidine gluconate gluconate that mass fraction is 5%, Continue to stir for 5 minutes and stir to obtain material liquid D;
e. Mix the feed solution A, feed solution B, feed solution C and feed solution D evenly, configure to 5000ml with purified water, and stir evenly to obtain the cCorsodyl Chlorhexidine Digluconate.