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Collagen Tripeptide

Molecular Formula:  

Formula Weight: 0

ZSpharmac: Collagen Tripeptide Cosmetic Raw Material Supplier

Product Name: Collagen Tripeptide
CAS No: 
Purity: 99%

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Basic Info

Product Name:Collagen Tripeptide
Other Names:Collagen Peptide
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
Provide:Collagen Tripeptide MSDS;
Collagen Tripeptide COA

What is Collagen Tripeptide?

Collagen peptide is derived from collagen through enzymatic hydrolysis, which breaks down its molecular chains. This process results in the formation of peptides, which are structural fragments that make up proteins. These peptides have a molecular weight of 200~300 Da, making them small and easily absorbable. Peptides serve as the molecular foundation of proteins and possess various physiological effects. Consequently, altering the amino acid structure leads to changes in the efficacy of the peptide. With thousands of different types, peptides exhibit diverse functions.

Collagen Tripeptide Uses

1. Antioxidant Properties
The development of antioxidants has garnered significant attention due to their potential in combating aging and various diseases associated with free radicals. Collagen peptides derived from fish skin collagen have been found to possess antioxidant properties, effectively reducing free radicals in the body and inhibiting disease and aging. Ma Huawei et al. conducted a study using the pyrogallol autoxidation method and the DPPH microplate reader method to measure the antioxidant properties of protein peptides. Their findings revealed that protein peptides exhibited excellent scavenging effects on superoxide anion free radicals, DPPH free radicals, and hydroxyl free radicals. Zhang Hanjun et al. further investigated the antioxidant properties of enzymatic hydrolysates under optimized conditions, discovering that different enzymatic solutions displayed varying abilities in scavenging hydroxyl radicals, with a degree of enzymatic hydrolysis exceeding 4% resulting in a scavenging rate exceeding 80%. Wang Qun et al. utilized an enzymatic method to prepare collagen peptides and determined their antioxidant properties through response surface experiments, ultimately identifying a process involving an enzyme amount of 1600 U/g, a pH value of 9.5, and a clearance rate of 60°C.

2. Whitening and Skincare
Collagen peptides have gained widespread use in cosmetics due to their beneficial effects on moisturization, water locking, and whitening. Kong Hui et al. investigated the acid leaching-water extraction method for obtaining salmon gelatin, followed by enzymatic hydrolysis to measure the moisturizing and water-absorbing properties of protein peptides. Their research demonstrated that gelatin peptides exhibited excellent moisturizing properties and possessed a certain whitening effect. Liu Qi et al. studied the function of cod collagen peptides and highlighted the presence of polar amino acids in collagen, which, after enzymatic hydrolysis, resulted in hydrophilic groups that could bind with water molecules, thereby providing the protein peptides with water absorption and retention functions. Additionally, Kong Hui et al. found that salmon protein peptides inhibited the activity of tyrosine, preventing melanin production and indicating their potential for whitening effects.

3. Stomach and Liver Protection
The stomach and liver play crucial roles in the human body, and due to factors such as stress and workload, many individuals experience issues with these organs. Protein peptides have been found to possess the ability to repair the gastric mucosa and liver. Wang Zhicong et al. conducted experiments that verified the ability of cod collagen peptides to reduce bleeding and ulcer index in the gastric mucosa. Liu Chenchen’s research revealed that collagen peptides regulated apoptosis and anti-apoptosis genes by inhibiting TNF-α gene expression, thereby protecting the liver. Teng Fangfang et al. concluded from their experiments that liver protection was achieved through antioxidant mechanisms and the reduction of apoptotic cells. Wang Jiabin et al. tested the inhibition of TNF-α by collagen peptides, which resulted in reduced apoptosis of liver cells and the release of oxygen free radicals and lysosomal enzymes by leukocytes, ultimately providing protection for the liver.

Study on Extraction Method of Collagen Tripeptide

Li Na and colleagues conducted a study on the fundamental characteristics of collagen from the swim bladder of Atlantic cod (Gadus macrocephalus) and Collagen Tripeptide prepared using three different extraction methods. The methods employed included low-temperature acid dissolution for acid-soluble collagen (ASC) extraction, hot water extraction for gelatin (GEL) extraction, and complex protease enzymatic hydrolysis for cod swim bladder peptide (SWP) preparation. The aim was to investigate the properties of collagen. The extracted collagen and collagen peptides were subjected to various analyses including sensory evaluation, SDS-PAGE electrophoresis, ultraviolet spectrum analysis, Fourier transform infrared spectrum analysis, amino acid composition analysis, and scanning electron microscopy analysis.

The results revealed that the extraction rates of ASC, GEL, and SWP collagen and collagen peptides were 42.15%, 72.20%, and 89.11%, respectively. The hydroxyproline contents were found to be 8.73%, 8.97%, and 7.94%. SDS-PAGE analysis showed that ASC consisted of at least 2 α chains and 1 β chain. GEL contained a small amount of α chain, while SWP exhibited degradation of both the α and β chains. The ultraviolet spectrum results indicated that all three proteins absorbed at a wavelength of 230nm. Scanning electron microscopy analysis demonstrated the presence of a certain cross-linked structure in ASC and GEL, whereas no cross-linked structure was observed in SWP.

In conclusion, the collagen and Collagen Tripeptide obtained through the three different extraction methods exhibited distinct properties.

Contact Us

About Products:
If you need the cosmetic raw material Collagen Tripeptide, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Collagen Tripeptide, our company, ZSpharmac will provide Collagen Tripeptide raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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