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Clotrimazole Solution CAS 23593-75-1

Molecular Formula: C22H17ClN2

Formula Weight: 344.84

ZSpharmac: Clotrimazole Solution Raw Material Supplier

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Product Name: Clotrimazole Solution
CAS No: 23593-75-1
Purity: 99%

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Basic Info

Product Name:Clotrimazole Solution
Other Names:Clotrimazole
CAS:23593-75-1
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Almost White Neat
EINECS No.:245-764-8
Storage:2-8°C
Provide:Clotrimazole Solution MSDS;
Clotrimazole Solution COA

What is Clotrimazole Solution?

Clotrimazole is an artificial azole antifungal medication that has inhibitory impacts on a range of pathogenic fungi as well as can also have antiseptic impacts at high concentrations. Clotrimazole inhibits the biosynthesis of fungal ergosterol as well as various other sterols by interfering with the activity of cytochrome P450; it harms the fungal cell membrane layer and also alters its leaks in the structure, triggering the loss of important intracellular substances; it can likewise hinder fungal triglycerides as well as phospholipids. Biosynthesis; this item can also prevent the task of oxidation and peroxidase, creating extreme accumulation of peroxide in cells, triggering degeneration as well as necrosis of the fungal subcellular framework. Clotrimazole has broad-spectrum antifungal task, and has excellent antibacterial results against epidermophyton, trichophyton, aspergillus, pigmented fungi, Cryptococcus and also Candida albicans, and also against Sporothrix schenckii as well as Blastomyces dermatitidis., Coccidioides immitis, Histoplasma, and so on also have particular antibacterial activity.

Clotrimazole Solution Property

Melting point 147-149°C
Boiling point 501.14°C (rough estimate)
density 1.1095 (rough estimate)
refractive index 1.5940 (estimate)
storage temp. 2-8°C
solubility Soluble in chloroform, DMSO, DMF and alcohols
pkapKa 4.7(EtOH 50%aq ) (Uncertain)
form neat
color White to Almost white
Water Solubility <10mg/L(25 ºC)

 

Clotrimazole Solution Clinical Application

Professional topical 1% clotrimazole lotion or option is made use of to treat skin infections such as candidiasis, tinea versicolor, athlete’s foot, as well as nail tinea. Clotrimazole vaginal tablets (100 mg) are administered to treat genital infections triggered by Candida fungus and Trichomonas. Negative effects include local irritation and also burning experience. Oral management is utilized to deal with deep fungal infections, but the adverse effects are serious, consisting of intestinal irritability, neutropenia, and also abnormal liver function.
1. Oral management: (1) For the therapy of candida fungus infection in the oropharynx. (2) For the avoidance of candida albicans infection in the oropharynx in individuals getting radiation treatment, immunocompromised or faulty individuals.
2. Topical application: (1) Candida fungus infection of skin. (2) Tinea pedis, tinea cruris and also tinea corporis brought on by Trichophyton, Microsporum as well as Epidermophyton; tinea versicolor caused by Pityrosporum pityrosporum, etc 3. Vaginal administration: (1) Vaginitis triggered by Yeast or other fungi. (2) Contagious leucorrhea triggered by yeast. (3) Genital second infection caused by germs conscious this medication, and so on.

Clotrimazole Solution Mechanism of Action

(1) By decreasing the activity of cytochrome P450, it prevents the biosynthesis of sterols such as ergosterol in the fungal cell membrane, harms the fungal cell membrane layer and alters its leaks in the structure, creating the leak of vital intracellular compounds.
( 2 )Clotrimazole Option can also inhibit the biosynthesis of fungal triacylglycerol as well as phospholipids.
( 3) It can still hinder the tasks of oxidase and also peroxidase, leading to too much buildup of hydrogen peroxide in cells, creating degeneration of fungal subcellular frameworks as well as cell necrosis.
( 4) For Candida fungus albicans, it can prevent its change from spores to invasive hyphae.

Several Synthesis Methods of Clotrimazole Solution

About Products:
If you need the cosmetic raw material Clotrimazole Solution, please contact our service staff directly and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Clotrimazole Solution, our company, ZSpharmac, will provide Clotrimazole Solution raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Clotrimazole Solution Quotation