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Chlorogenic Acid Powder CAS 327-97-9

Molecular Formula: C16H18O9

Formula Weight: 354.31

ZSpharmac: Chlorogenic Acid Powder

Product Name: Chlorogenic Acid Powder
CAS No: 327-97-9
Purity: 99%

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Basic Info

Product Name: Chlorogenic Acid Powder
Other Names: Chlorogenic Acid
CAS: 327-97-9
Place of Origin: Shandong, China
Brand Name: ZSpharmac
Type: Cosmetic Raw Materials
Appearance: White to Almost White Powder
EINECS No.: 206-325-6
Storage: 2-8°C
Provide: Chlorogenic Acid Powder MSDS;
Chlorogenic Acid Powder COA

What is Chlorogenic Acid Powder?

Chlorogenic acid, chemically known as 3-O-Caffeoylquinic acid, is a complex phenolic acid compound with a molecular formula of C16H18O9 and a molecular weight of 354.309 Da. Its CAS registration number is 327-97-9. Chlorogenic acid is formed by esterification of caffeic acid and quinic acid, in which caffeic acid is an aromatic acid with an unsaturated double bond, while quinic acid is a cyclic structure with multiple hydroxyl groups.

Chlorogenic acid has three unstable structural parts, namely ester bonds, unsaturated double bonds and polyphenols, which give it a variety of biochemical activities and physical properties. It is a pale yellow solid at room temperature and usually exists in the form of a hemihydrate, that is, it contains one water molecule and loses water molecules to become an anhydrous compound when heated to 110°C. Chlorogenic acid has good solubility, with a solubility of about 4% in water at 25°C and higher solubility in hot water. It is easily soluble in ethanol and acetone, but has a very low solubility in ethyl acetate.

Chlorogenic Acid Powder Property

Melting point 210 °C (dec.) (lit.)
alpha -36 º (c=1, H2O)
Boiling point 407.55°C (rough estimate)
density 1.3594 (rough estimate)
refractive index -37 ° (C=1, H2O)
storage temp. 2-8°C
solubility Soluble in ethanol and acetone.
form Powder, Crystals, Needles and/or Chunks
color White to almost white


Chlorogenic Acid Powder Uses

Pharmaceutical field
In the pharmaceutical field, Chlorogenic Acid Powder is used as an active ingredient or intermediate for the preparation of a variety of drugs. It has a variety of pharmacological effects, such as:
Antibacterial and antiviral: Chlorogenic acid and its derivatives can inhibit the growth of a variety of microorganisms and can be used to treat infectious diseases.
Antioxidant: Chlorogenic acid can scavenge free radicals, reduce oxidative stress, and protect cells from damage.
Anti-tumor: Studies have shown that chlorogenic acid has the ability to inhibit tumor growth.
Cardiovascular protection: Chlorogenic acid helps lower blood pressure and blood lipids, prevent arteriosclerosis, and protect heart health.

Food and beverage industry
Chlorogenic Acid Powder is a natural antioxidant that can extend the shelf life of food, prevent oil oxidation, and improve taste. It is commonly found in coffee, tea, and other plant-based foods, providing them with additional health benefits. In the beverage industry, chlorogenic acid can improve the nutritional value of products, such as being added to functional beverages.

Cosmetic industry
Due to its antioxidant and anti-inflammatory properties, Chlorogenic Acid Powder is used as an active ingredient in cosmetics for skin care and anti-aging products. It can protect the skin from environmental factors, reduce wrinkles, brighten the skin tone, and improve skin texture.

Agriculture and Pesticides
Chlorogenic Acid Powder can be used as a biopesticide in agriculture, which has an inhibitory effect on certain pests and pathogens, while being environmentally friendly and reducing the use of chemical pesticides.

Other Applications
Chlorogenic Acid Powder may also be used in the chemical industry as a raw material for fine chemicals, and as a standard substance for analytical testing in scientific research.

Chlorogenic Acid Powder in Cosmetics

  1. Antioxidant and Anti-Aging
    Chlorogenic Acid Powder is an effective free radical scavenger that can neutralize free radicals generated by ultraviolet (UV) radiation, environmental pollution, and daily stress. Excessive free radical production can lead to accelerated skin aging, fine lines, wrinkles, and pigmentation. Chlorogenic acid protects skin cells from oxidative stress through its antioxidant properties, thereby delaying the skin aging process and maintaining skin elasticity and radiance.
  2. Sunscreen and Photoprotection
    Chlorogenic Acid Powder has a certain UV absorption capacity and can be added to sunscreen or daytime skin care products as an auxiliary sunscreen ingredient to enhance the product’s protection against UVA and UVB rays. It not only absorbs UV rays, but also reduces skin inflammation and erythema reactions caused by UV rays, providing additional photoprotection.
  3. Skin Toning and Whitening
    Chlorogenic Acid Powder helps to even out skin tone and lighten spots by inhibiting the activity of tyrosinase and reducing the production of melanin. This mechanism of action makes chlorogenic acid one of the key ingredients in whitening and spot management formulas, helping to improve skin pigmentation problems and enhance skin brightness.
  4. Anti-inflammatory and soothing
    For sensitive or inflammatory skin, the anti-inflammatory properties of Chlorogenic Acid Powder can relieve skin redness, itching and discomfort, and promote the healing of damaged skin. It can reduce the skin’s response to external stimuli and enhance the skin barrier function, making the skin more stable and healthy.
  5. Moisturizing and nourishing
    Although Chlorogenic Acid Powder itself is not a direct humectant, it can indirectly promote the skin’s moisturizing effect by maintaining the skin’s natural hydration through antioxidant effects. Healthy skin barrier function helps lock in moisture and reduce transepidermal water loss (TEWL), thereby keeping the skin hydrated and soft.
  6. Hair care
    In addition to skin care, Chlorogenic Acid Powder is also used in hair care products to reduce hair damage caused by hair dyes, protect hair from chemical treatments and environmental factors, and maintain hair strength and shine.


National Center for Biotechnology Information. PubChem Compound Summary for CID 1794427, Chlorogenic Acid. https://pubchem.ncbi.nlm.nih.gov/compound/Chlorogenic-Acid. Accessed July 4, 2024.

As a company specializing in the production and supply of Chlorogenic Acid Powder raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the required Chlorogenic Acid Powder raw materials to support your production and research and development.

We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.

If you have any needs or are interested in our products, please contact our service staff directly, and we will wholeheartedly provide you with the best service and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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