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Zhishang Chemical

Chitin Himedia CAS 1398-61-4

Molecular Formula: C6H11NO4X2

Formula Weight: 161.16

ZSpharmac: Chitin Himedia Supplement

Product Name: Chitin Himedia
CAS No: 1398-61-4
Purity: 99%

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Basic Info

Product Name:Chitin Himedia
Other Names:Chitin
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Purified Powder
EINECS No.:215-744-3
Storage:Room Temp
Provide:Chitin Himedia MSDS;
Chitin Himedia COA

What is Chitin Himedia?

Chitin Himedia is a nitrogen-containing polysaccharide, likewise known as chitin, chitin, chitin, chitin, keratin, and so on. It is the 2nd most abundant biopolymer in nature, extensively dispersed, and is one of several lower animals. Especially the essential parts of the covering of arthropods such as shrimp, crab, bugs, and so on, the shrimp shell contains concerning 15% to 30%, as well as the crab covering includes about 15% to 20%. It is also a part of the cell membrane layer of reduced plant fungis, lichens, green algae, yeast, jellyfish and squid. With an estimated yearly biosynthesis of more than 1 billion lots, it is a substantial renewable energy. Look is white or somewhat yellow clear body, it is 2-acetylglucosamine polymer, its chemical structure resembles all-natural cellulose, in addition to the visibility of hydroxyl in the particle, it additionally includes acetylamino as well as amino functional teams, which can be customized It has lots of groups and also has richer functional homes than cellulose as well as its derivatives. It is insoluble in water, ethanol, ether, salt as well as dilute acid and also alkali; it is soluble in acetic acid and responds with concentrated caustic soda service to develop a lustrous colloid The soluble Chitin Himedia (likewise known as polyaminoglucose, chitosan, sugar liquid chitin, chitosan, and so on), they can be made use of for: ① ion exchange material for purifying water and extracting uranium from seawater; ② gel chromatography column fillers and also molecular screens; ③ prep work of biologically or enzymatically degradable food product packaging films or soluble in vivo medical threads; ④ water-retaining representatives for cultivating plants or microbes; Solid color.

Chitin Himedia is insoluble generally acid and antacids, and also its chemical buildings are very secure, which is an important factor that restricts its lasting growth. The deacetylated chitosan is white to light yellow powder. Although it is insoluble in water, alkali remedy as well as natural solvent, it is soluble in water down acid remedy, consisting of not natural thin down acid (hydrochloric acid, nitric acid, and so on) As well as organic weaken acids (acetic acid, lactic acid, formic acid, ascorbic acid, malic acid, etc). In the liquid remedy of polyvalent natural acids such as citric acid as well as tartaric acid, it dissolves when warmed at high temperature, and also comes to be gelatinlike when the temperature goes down.

Chitin Himedia is a polysaccharide compound 2-amino-2-deoxy-D-glucose β( 1 → 4) Polymer, particularly chitosan. The chemical frameworks of Chitin Himedia, chitosan, as well as cellulose are similar in framework amongst the 3. Since the existing technology can not totally deacetylate chitin right into 100% chitosan, and also it is challenging to completely divide the two, the existing chitosan items are typically a blend of Chitin Himedia as well as chitosan, yet the chitosan content is called for to be more than 60%. Nevertheless, chitosan as a functional food base needs a chitosan web content of greater than 85%.

Chitin Himedia Property

Melting point >300°C (dec.)
Boiling point 737.18°C (rough estimate)
density 1.3744 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Room Temp
solubility dilute aqueous acid (pH <6.5).: soluble
form purified powder
color White
Water Solubility insoluble


Chitin Himedia Uses

  1. Chitin Himedia is pharmaceutical excipients, clinical sutures, etc. Among them, as an auxiliary material, it can be made use of as a sustained launch representative, a lubricating substance, and a covering representative. Microparticles, tablets, pills, microfilms, etc. of the corresponding medicines can be prepared by straight compression, damp granulation or layer. It can be made into dialysis membrane, ultrafiltration membrane and turn around osmosis membrane; the cross-linked complicated with fiber can be utilized as molecular filter. With glutaraldehyde as a cross-linking representative, it can be debilitated with numerous enzymes or microbial cells, such as incapacitated asparaginase. It can be utilized as man-made skin, fabricated capillary, artificial kidney, etc. Chitosan can prevent stomach ulcer, lower cholesterol and blood lipids.
  2. Chitin Himedia is a crucial resources for the prep work of chitosan as well as glucosamine series products. Chitin and also its by-products have important uses in medicine, chemical industry, natural food, and so on, and have broad application prospects. It can be utilized in the preparation of soluble chitin and glucosamine, as an additive in cosmetics as well as functional foods, and in the prep work of photo solutions.
  3. Chitin Himedia as adsorption clarifier and thickener. my nation states that it can be used in jam, the maximum use is 5.0 g/kg; the maximum use in lactic acid microorganisms drink is 2/5g/kg; the maximum usage in hydrogenated vegetable oil, mayonnaise, peanut butter, sesame paste, gelato and also non-dairy powder is 2.0 g/kg; The optimum amount made use of in vinegar is 1.0 g/kg; the optimum quantity utilized in beer is 0/4g/kg.
  4. Chitin Himedia is made use of as thickener, stabilizer, tannin cleaner. Primarily utilized for fruit juice, fruit a glass of wine, and so on, to avoid discoloration and remove astringency. It can also be utilized as a binder, glazing agent, filler, film-forming representative and also emulsifier.
  5. Chitin Himedia was separated from shrimp shell chitin for chitinase analysis. It is a polysaccharide made up of N-acetyl-D-glucomasine as well as is likewise utilized in the manufacture of glucosamine and chitosan. High quality needs filtration before use as a substratum for chitinase.
  6. Chitin Himedia is an essential resources for the prep work of chitosan and also glucosamine collection items; chitin drawn out from shrimp coverings is suitable for chitinase evaluation; made use of for immobilization of α-amylase; production of fructose by immobilizing inulinase; in In microbial manufacturing of N, N’-diacetylchitobiose, keratin periodontal is prepared.
  7. Chitin Himedia A polysaccharide present in the coverings of several microorganisms, especially shellfishes.

The Role of Chitin Himedia

Therefore, in the face of the invasion of various viruses, bacteria, parasites and even cancer, as long as the immune function in the human body can be activated at any time, it can effectively resist the invaders. Chitosan has higher protein adsorption capacity; chitosan has affinity and solubility, and is suitable for the production of various derivatives; chitosan exhibits selective and highly inhibiting the growth of oral Streptococcus, without affecting the Growth of other beneficial bacteria. Repair cells, induce cells and activate cells, it can repair from the cell membrane. After the cell membrane is repaired, the cells are healthy and the cells are activated, so chitin has the function of activating cells.

Chitin Himedia, a positively charged polycationic electrolyte, can adsorb to the surface of tumor cells and act by activating the immune system, thereby inhibiting the growth and metastasis of tumor cells. We all know that cancer toxins can lead to a decrease in serum iron, which leads to anemia. In addition, cancer toxins can also lead to satiety nerve excitation and decomposition of body fat, resulting in decreased appetite, causing patients to be scrawny and miserable. Chitin can inhibit cancer toxins, so that cancer patients will not be anemia, and have a good appetite, which relieves pain for cancer patients. Generally, the body fluids of cancer patients are acidified, but after eating chitin, the body fluids will be weakly alkaline, and the phagocytes will be active at the pH value of 7.4 in the body fluids, and can phagocytose cancer cells in large quantities.

Professor Tokura, a Japanese oncologist, discovered 20 years ago that cancer cells cannot metastasize by themselves, and can only metastasize when combined with an understanding molecule. This molecule is negatively charged, while chitin is a cationic edible fiber with positive Therefore, it can be combined with the adhesive molecules first, so that the cancer cells cannot be combined with the adhesive molecules, thereby effectively inhibiting the metastasis of cancer cells.

10 years ago, a professor told a chitin academic seminar that in Japan, chitin has been used as an injection-inhibition of cancer cell metastasis in clinical practice for many years, but it is generally unaffordable to the common people. An injection would cost $10,000, three injections a day for three months to heal. However, the capsules are still affordable for the common people, especially the health care amount is cheaper, only more than two yuan a day.

Chitin has a strong adsorption effect, which can absorb excess sugar and excrete it from the body. Chitin can adjust the acid-base balance and repair the edema, degeneration and fibrosis of pancreatic islet tissue. People with diabetes are most concerned about blood sugar, but it is the glucose in the blood that is directly related to diabetes, not all sugars. The metabolic decomposition product of chitosan oligosaccharide, glucosamine, can directly activate islet beta cells, increase the number and function of islet beta cells, and restore pancreatic function. Acidic constitution is the main culprit that induces various diseases, especially diabetes. Experiments have shown that for every 0.1 increase in the PH value of human body fluids, the activity of insulin will increase by 30%. Chitosan oligosaccharide is an alkaline polysaccharide, which can increase the pH value of the human body and present a weak alkaline that is beneficial to human health. Chitooligosaccharide has a strong adsorption effect, which can absorb excess sugar in food and excrete it from the body to prevent blood sugar from rising. At the same time, chitosan oligosaccharide can prevent and improve the complications of diabetes and reduce the incidence of cataract, retinal degeneration and fundus disease.

Chitin can regulate serum total cholesterol and triglycerides. Among them, high-density lipoprotein can bind the chloride ion, the culprit of hypertension, and excrete it from the body, which can prevent various diseases caused by hypertension. One of the most influential factors in high blood pressure is chloride ions. It is usually ingested through table salt. Many people have been consuming too much salt since 2010. Chitosan excretes chloride ions through its own adsorption between chloride ions and ammonium ions. As I mentioned just now, chloride ions are the culprit of high blood pressure. Chitosan oligosaccharides can combine with negatively charged chloride ions and excrete them out of the body by virtue of their unique positive-charged properties, thereby reducing blood pressure. Long-term use can remove acidic wastes in the blood, soften blood vessels, enhance elasticity, and fundamentally regulate and relieve blood pressure. The uniqueness of chitosan oligosaccharide also includes its two-way regulation of blood pressure and blood sugar, which means that if you have low blood sugar and low blood pressure, it will activate its own powerful function to quickly adjust your blood pressure to normal blood sugar. Therefore, chitosan can help prevent high blood pressure, especially those who consume excessive salt.

Chitin can prevent the digestion and absorption of lipids, adsorb cholesterol and expel it from the body, promote the conversion of cholesterol, and reduce cholesterol, thereby preventing and improving cardiovascular and cerebrovascular diseases. Chitosan lowers cholesterol by two mechanisms. First, chitosan inhibits the activity of lipases that aid in fat absorption. Lipase breaks down fat for the body to absorb. Another is the excretion of bile acids. Once bile acids are excreted, cholesterol in the blood is used to make bile acids. These two mechanisms make chitosan a strong cholesterol scavenger. and without any side effects.

Chitin can expel uncharged polar particles, such as low-density lipoprotein, cholesterol, glycerolipid and other wastes from the body in the form of polar adsorption. In the form of electrostatic adsorption, negatively charged particles, such as fatty acids, bile acids, lactic acid, and chloride ions, are excreted from the body.

Chitin Himedia will continue to play the function of scavenging free radicals and inhibiting peroxidation in the body; it will reduce the damage to the cells of living organisms and interfere with the function of cells, which will undoubtedly delay the aging of cells. Free radicals have high chemical activity and are intermediate metabolites of various biochemical reactions in human life activities. In order to prevent the accumulation of excessive free radicals in the body, the human body will inevitably produce some substances that can eliminate these free radicals – free radical scavengers. He Deqing of the 35th Hospital of the People’s Liberation Army and others have done animal experiments on chitosamine scavenging free radicals and inhibiting peroxidation. From the test results, chitosamine will continue to play the function of scavenging free radicals and inhibiting peroxidation in the body.

Chitin can inhibit a large number of free radicals produced by radiation damage, enhance immune function, and resist infection. It can reduce the toxic and side effects of cancer patients during radiotherapy and chemotherapy, and prevent occupational diseases caused by exposure to radiation. A remarkable property of chitosan is its adsorption capacity. Many low molecular weight materials, such as metal ions, cholesterol, triglycerides, bile acids, and organic mercury, can be adsorbed by chitosan. In particular, chitosan can adsorb not only magnesium and potassium, but also zinc, calcium, mercury and uranium. The adsorption activity of chitosan can play a role selectively. Too high concentrations of these metal ions in the human body are harmful. For example, high concentrations of copper ions in the blood can lead to copper poisoning and even carcinogenic consequences. Chitin is a macromolecular substance. The solution of macromolecular substance is viscous at a certain concentration. At the same time, due to its special molecular structure, its surface absorption capacity is also strong. More importantly, in the molecular structure of chitin There are a large number of polar groups, which can adsorb many uncharged polar particles and excrete them from the body.

The inhibitory effect of chitin on pathogenic organisms has long been studied. Human epidermal bacteria were killed when cultured on agar plates treated with powdered chitosan, chitin or crab shells. Zheng Lianying, Institute of Biochemical Engineering, Zhejiang University, etc., proposed the antibacterial mechanism of chitosamine: chitosamine penetrates into the cell body, absorbs the cytoplasm with anions in the cell body, and flocculates, disturbing the normal physiological activity of the cell, thereby killing Kill bacteria.

Chitin can obviously promote the growth of wound granulation tissue, improve the healing speed, inhibit and kill various bacteria, promote endothelial growth, reduce fibrous tissue proliferation and scar formation. Chitin has a wide range of application value in the surgical field such as the treatment of trauma, burns, bedsores, etc.

Chitin is a natural macromolecule compound with good moisturizing properties, adsorption properties, tackifying properties, antibacterial properties, antistatic properties, film-forming properties, combing properties, softness, and the functions of activating and repairing cells.

Chitin has the functions of improving immunity, detoxifying and detoxifying, and activating cells. Chitin can not only activate the biological enzymes in the liver to prevent the occurrence of hepatitis and fatty liver, but also has the function of strengthening immunity, preventing the absorption of cholesterol and neutral fat, and exerting a powerful function of cell rejuvenation.

Through the basic group of chitin, the acidic body fluid that is not conducive to health can be restored and adjusted to a weak alkaline level that is beneficial to health, improving the acidic constitution and making it less prone to diseases. Therefore, even healthy and sub-healthy people often consume chitin, which will play a role in health care. Human blood or other body fluids maintain a certain pH value. Generally speaking, body fluids should be weakly alkaline, otherwise it is easy to get sick. Therefore, maintaining a slightly alkaline body fluid environment is an essential condition for maintaining human health. After taking chitosan, the alkaline gene of chitosan can restore and adjust the acidic body fluid that is not conducive to health to a weak alkaline level that is beneficial to health, improving the so-called acidic body fluid, and people are less prone to diseases.

In orthopaedic treatment, chitin should be the first to be used for arthritis. Chitin derivatives can promote the synthesis of proteoglycans in chondrocytes, increase the viscosity of joint synovial fluid, improve the metabolism of articular cartilage, and accelerate the formation of osteoblasts and fibrous callus. Production of polysaccharides, collagen fibers and hyaluronic acid, which are essential for articular cartilage production. On the other hand, synovial fluid is generated by acting on the synovial membrane of the joint, thereby continuously lubricating the surface of the articular cartilage, reducing friction, and making the joints flexible and free. At the same time, synovial fluid, as a carrier of joint nutrients, can provide sufficient nutrition for articular cartilage, which is beneficial to the recovery of osteoarthritis and the healing of fractures.

Chitin becomes gelatinous after dissolving in gastric juice, forming a protective layer that is not easily separated on the gastrointestinal wall, inhibiting the stimulation and corrosion of gastric acid on the damaged surface, and promoting ulcer repair and healing.

Chitin can promote the growth of bifidobacteria, inhibit the growth of pathogenic bacteria and spoilage bacteria in the intestine, prevent intestinal dysfunction and prevent intestinal infection, and improve the absorption function of nutrients. Chitin can be decomposed into chitosan oligosaccharides with smaller molecular weight in the intestine. This oligosaccharide has been confirmed by research as a source of nutrients for beneficial bacteria in the intestine, which can promote the growth and reproduction of beneficial bacteria in the intestine. This has a good effect on gastrointestinal diseases such as indigestion caused by long-term use of antibiotics, resulting in dysbiosis. Infants and young children are prone to indigestion of dairy products, and chitin is also required to be corrected at this time.

When “chitin” is converted into oligoglucosamine and glucosamine under the action of enzymes, the physiological activity is significantly increased, and the vagus nerve and parasympathetic nerve are stimulated to increase the excitability, so that the arterioles and tiny arteries of the corresponding tissues are expanded, the blood speed is accelerated, and the blood Increased flow improves microcirculation and specific functions are enhanced. The level of secretin in endocrine organs increases, and the secretory function of glandular cells is enhanced. A variety of physiologically active substances produce a good regulatory effect accordingly.

“Chitin” can stop bleeding has been clinically proven. The mechanism is that chitin can activate some links in the coagulation process. The positively-charged amino groups of chitin interact with receptors that express negatively-charged amino acid residues in nerve cells to promote the coagulation process. Aggregates with “chitin” in the affected area and stimulates platelets to accelerate the coagulation process.

Chitin Himedia Production Method

Chitin for industrial applications is obtained from the coverings of shellfishes (freshwater and also aquatic shrimp, crabs, and so on). Some spin-offs of the developing industry are likewise basic materials for chitin. For instance, a certain quantity of chitin can be given in the raffinate of citric acid generated by fermentation of Aspergillus niger, along with in the fermentation brew of Mucor, Brakesula and also Z. oospora. Extraction of chitin: Get rid of and clean up the flesh of shrimp and crab coverings. Take in 4-6% hydrochloric acid to dissolve and also soften the inorganic salts in the covering. Wash with water, and after that use 10% sodium hydroxide solution to eliminate healthy protein. After washing once again, usage 1% KMnO4 to bleach and also oxidize to get rid of contaminations. After the 3rd cleaning, the recurring MnO4 was eluted with 1% NaHSO3, after that completely cleaned with water and dried to acquire pure chitin. Resources intake (kg/t) shrimp and crab shells 1200035% commercial hydrochloric acid 13000 caustic soda (95% solids) 1500 potassium permanganate 135 salt bisulfite 340.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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