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Cetylpyridinium Chloride CAS 123-03-5

Molecular Formula: C21H38ClN

Formula Weight: 339.99

ZSpharmac: Cetylpyridinium Chloride Raw Material Supplier

Product Name: Cetylpyridinium Chloride
CAS No: 123-03-5
Purity: 99%

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Basic Info

Product Name:Cetylpyridinium Chloride
Other Names:HexadecylPyridinium Chloride
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:HexadecylPyridinium Chloride
EINECS No.:204-593-9
Storage:Room Temperature
Provide:Cetylpyridinium Chloride MSDS;
Cetylpyridinium Chloride COA

What is Cetylpyridinium Chloride?

Cetylpyridinium Chloride is a quaternary ammonium compound commonly used as a disinfectant, bactericide and antiseptic. Its chemical structure consists of a long-chain alkyl group (in this case a hexadecyl group, i.e. C16H33-) attached to a pyridine ring, with a chloride ion as a counterion. Due to its cationic nature, Cetylpyridinium Chloride has strong antibacterial activity due to its ability to disrupt the membrane structure of bacteria and viruses.

Cetylpyridinium Chloride Property

Melting point 77°C
Boiling point 496.25°C (rough estimate)
density 0.9362 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.6000 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Freely soluble in water; very soluble in chloroform; very slightly soluble in ether; insoluble in acetone, acetic acid, and ethanol.
form White Crystalline Powder
Odorat 100.00?%. pyridine
Water Solubility 111g/L at 20℃


Cetylpyridinium Chloride Applications

Personal hygiene and care products:
Oral care: Often used in mouthwash, toothpaste and oral spray, it can effectively inhibit the growth of oral bacteria, reduce plaque formation, and prevent dental caries and bad breath.
Skin Cleansing: Added to hand soap, shower gel and facial cleansing products to provide antibacterial effects and protect skin health.
Wound care: Used in disinfectant sprays and band-aids to promote wound cleaning and prevent infection.

Family and Public Health:
Surface disinfectant: As a highly effective disinfectant ingredient, it is used for cleaning hard surfaces in kitchens, bathrooms, hospitals, schools and other places to kill bacteria and viruses.
Air purification: Some air fresheners and disinfectant sprays use Cetylpyridinium Chloride to reduce the amount of microorganisms in the air.

Medical insurance:
Surgical Disinfection: Skin preparation and surgical instrument disinfection before surgery to reduce the risk of surgical site infection.
Ophthalmic use: Used in eye drops to treat eye infections and combat conditions such as bacterial conjunctivitis.
Veterinary uses: In the field of animal hygiene, used in pet disinfectant products and skin cleaning before veterinary surgery.

Industrial applications:
Water treatment: As a water treatment agent, it can effectively control the growth of microorganisms in water systems, such as cooling towers and circulating water systems.
Textile treatment: used for antibacterial finishing of textiles to increase the antibacterial and deodorizing functions of clothing and bedding.
Plastics and coatings: Added to plastic products and coating materials to give products long-lasting antibacterial properties.

Seed treatment: used to disinfect seeds and prevent seed diseases caused by bacteria and fungi.
Veterinary drugs: used as feed additives to control pathogenic microorganisms in the digestive tract of animals and improve animal health.

Prominent Applications of Cetylpyridinium Chloride in Cosmetics

Antiseptic properties: Cetylpyridinium Chloride, due to its powerful broad-spectrum antibacterial activity, can effectively inhibit the growth of bacteria and fungi in cosmetics and extend the shelf life of the product. This is especially important for water-based cosmetics, as moisture is an ideal environment for microorganisms to thrive. By limiting the activity of microorganisms, it helps maintain the stability and safety of cosmetics and protects consumers from harmful microorganisms.

Oral care products: In oral hygiene products such as mouthwash and toothpaste, Cetylpyridinium Chloride can reduce the number of bacteria in the oral cavity, especially those that cause periodontal disease and bad breath, thereby providing additional oral protection and freshening breath effects.

Antibacterial skin care: In certain skin care products, such as anti-acne products, body care and foot care products, Cetylpyridinium Chloride is used to target bacteria on the skin surface, reducing the risk of skin inflammation and infection, especially in those susceptible to bacteria. Skin conditions such as acne or other skin infections.

Mildness and Compatibility: Despite its potent antimicrobial properties, Cetylpyridinium Chloride is relatively low irritant to skin and eyes at appropriate concentrations, making it an ideal preservative in personal care products requiring long-term skin contact. choose. However, optimization of its concentration and formulation is key to ensure the product is both effective and safe.

Odor control: In deodorizing products, Cetylpyridinium Chloride not only inhibits the growth of bacteria that cause odor, but also directly neutralizes or masks bad odors, providing a lasting sense of freshness.

Cetylpyridinium Chloride Advantages and Features

Efficient antibacterial properties: Cetylpyridinium Chloride is a broad-spectrum antibacterial agent that has efficient inhibitory and killing effects on a variety of bacteria, fungi and certain viruses. Its cationic nature allows it to interact with the negatively charged cell membranes of microorganisms, disrupting the cell membrane structure, resulting in the death of the microorganisms.

Good stability: Cetylpyridinium Chloride remains stable over a wide pH range (usually under neutral to slightly alkaline conditions) and under different temperature conditions, which allows it to remain stable in a variety of formulations and environments Effective antibacterial properties.

Water solubility and surface activity: As a quaternary ammonium salt, Cetylpyridinium Chloride has good water solubility, is easy to prepare, and has certain surface activity, which helps clean and disperse dirt while improving the stability of the formula.

Long-lasting effect: Due to its molecular structure, Cetylpyridinium Chloride forms a protective film on surfaces, providing continued antimicrobial protection even after washing, which is particularly important in oral care and skin protection products.

Versatility: In addition to being a preservative, Cetylpyridinium Chloride can also be used as a mouth freshener, deodorant, anti-inflammatory ingredient and, in some cases, an antistatic agent, reflecting its wide range of applications in different fields.

Environmental adaptability: At specific concentrations, Cetylpyridinium Chloride is considered environmentally friendly because it is easily degraded in the natural environment, reducing the long-term burden on the environment.


National Center for Biotechnology Information (2024). PubChem Patent Summary for US-6471948-B1, Toothpaste compositions containing cetylpyridinium chloride. Retrieved May 13, 2024 from https://pubchem.ncbi.nlm.nih.gov/patent/US-6471948-B1.

As a company specializing in the production and supply of Cetylpyridinium Chloride raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the Cetylpyridinium Chloride raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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