Zhishang Chemical

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Zhishang Chemical

Carnosic Acid CAS 3650-09-7

Molecular Formula: C20H28O4

Formula Weight: 332.43

ZSpharmac: Carnosic Acid Supplier

Product Name: Carnosic Acid
CAS No: 3650-09-7
Purity: 99%

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Basic Info

Product Name:Carnosic Acid
Other Names:Carnosic Acid (Synthetic)
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Powder
EINECS No.:609-253-7
Storage:Inert Atmosphere,Store in Freezer, Under -20°C
Provide:Carnosic Acid MSDS;
Carnosic Acid COA

What is Carnosic Acid?

Carnosic acid is suitable for antioxidation of oil-soluble ingredients. Used in seasoning sauce, family pet food and also feed, it has anti-oxidation and anti-aging results; it has solid weight-loss as well as lipid-lowering results; it can treat cardiovascular diseases as well as anti-cancer effects.
Rosemary (Rosemarinus), a natural herb of the Labiatae household, is native to southern European nations. It is introduced and also grown in Hunan, Guizhou, Hainan, Guangxi, Guangdong as well as various other districts and also cities in my nation. It includes carnosic acid, rosmanol, and rosmarinic acid., carnosol, epi-rosmanol, iso-rosmanol, rosmarinol and other energetic components, among which the high-efficiency antioxidant substances are carnosic acid, rosmanol and also carnosol, and so on. Fat-soluble rosemary extract is light yellow to tan powder or brownish paste, insoluble in water, soluble in ethanol and oil; water-soluble rosemary essence is brown powder, with a special smell of rosemary. Great heat resistance (stable at 200 ° C )and UV resistance, which can efficiently avoid the oxidation of oil.
Rosemary remove can be split into oil-soluble (anti-oxidant) and water-soluble (antioxidant as well as preservative), the active ingredient of the former is mainly carnosic acid, and also the latter is generally rosmanol. Rosemary extract is natural and also non-toxic, and its antioxidant effect is a lot greater than that of existing natural anti-oxidants such as vitamin C, vitamin E, as well as tea polyphenols, and also is 2 to 4 times that of unnaturally synthesized anti-oxidants BHA and BHT. Stable, difficult to decay, can stand up to heat from 190 ° C to 240 ° C, entirely conquer the fatal weakness of the majority of natural anti-oxidants such as vitamin C and also tea polyphenols, which are disintegrated at heat, so compared with various other similar items, it has an extra reliable wide spectrum The advantages. The researchers located that at 300mg/kg rosemary remove, its antioxidant activity amounted 200mg/kg BHA, higher than 100mg/kg tocopherol. Usually, its antioxidant capability increases with the increase of the included quantity, however when the concentration is high, it can cause precipitation of oil and discoloration of water-containing food.
The antioxidant feature of rosemary primarily hinges on its capability to relieve singlet oxygen, feed on cost-free radicals, chelate steel ions as well as synergistic results of organic acids.

Carnosic Acid Property

Melting point 190°C(lit.)
Boiling point 506.4±50.0 °C(Predicted)
density 1.184±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
form powder
color yellow


Carnosic Acid Uses

  1. Carnosic acid is used for material determination/identification/pharmacological experiments, and so on.
    Medicinal results: appropriate for anti-oxidation of oil-soluble components, with anti-oxidation and also anti-aging results; solid weight reduction as well as lipid-lowering effects; therapy of heart diseases as well as anti-cancer effects.
  2. Carnosic acid is As a resources for skin treatment products, it has actually long been sold in European as well as American countries.

Pharmacological Effects of Carnosic Acid

(1) Anti-bacterial result
Research studies have really shown that carnosic acid has different levels of repressive outcomes on Staphylococcus aureus, Escherichia coli, Bacillus subtilis and Hansenula, as well as can be used as a food chemical.
( 2) Antioxidant impact
Carnosic acid has good cost-free extreme scavenging along with anti-oxidation influences Its DPPH, ABTS cost-free radical scavenging capacity in addition to iron decline antioxidant ability are more powerful than VE, a little weak than synthetic antioxidant TBHQ; its minimizing capacity is stronger than VE as well as likewise TBHQ. Carnosic acid is fat-soluble, which can effectively inhibit the advancement of peroxides in oils and the decay of polyene fats, consequently expanding the life span of oils. Additionally, the study located that carnosic acid can appropriately feed on oxygen free radicals in mouse liver cells, reduce the manufacturing of lipid peroxides, consequently supporting the cell membrane layer; carnosic acid can likewise stop the oxidation response of low-density lipoprotein, which can efficiently quit The event of atherosclerosis.
( 3) Various other impacts.
Studies have discovered that carnosic acid can hinder the spreading of HL-60 cells, and also it is expected to become a new drug for the therapy of hematological hatreds, for the treatment of cardiovascular diseases as well as anti-cancer. Kaloustian and others introduced that rosemary extracts such as carnosic acid have particular restorative effects on heart disease as well as respiratory diseases, have anti-bacterial results, and also can additionally hinder HIV infection. Ninomiya et al. reported that carnosic acid and other rosemary removes, along with properly managing fat absorption to manage individuals’s weight, thereby attaining weight reduction, can also treat swelling, treat aching throat, deal with indigestion, and also avoid maturing Dementia, treatment of diabetic issues, and also promo of nerve growth factor production, etc.

The Application Prospect of Carnosic Acid

Carnosic acid is the key energetic ingredient of rosemary antioxidant accepted for use in my nation. As a fat-soluble all-natural anti-oxidant, carnosic acid is much above fabricated antioxidants in regards to maintaining oil., can be utilized in oil as well as fat-containing food, biomedicine, chemical market, cosmetics as well as also feed, etc, along with protecting against or delaying the oxidation of oil or oil-containing food, boosting the stability of food as well as also prolonging the storage time of storage, it can in addition be used as meat as well as flavoring for fish.
In Japan, rosemary extract is utilized in high-temperature fried foods to prevent oxidation effects and prevent photodeterioration after packaging, as well as can also be made use of in frozen foods to suppress dubious scent; in Europe, rosemary remove is also used It is made use of to stop the oxidation of ham and sausage products. A new watered down flavoring oil product with rosemary extract is applied, which is extremely suitable for meat products.
After years of research study, Microherb has efficiently divided high-purity carnosic acid (Carnosicacid) and also rosmarinic acid (Rosmarinic acid) with a web content of more than 90% by using modern Chinese medicine extraction technology and advanced chromatographic separation innovation for pharmacological, toxicological and scientific applications. Applied experimental study as well as commonly made use of in medication as well as health care and also everyday chemical industry.

About Products:
If you need Carnosic Acid, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Carnosic Acid manufacturer and supplier, ZSpharmac will provide Carnosic Acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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