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Calcium Propionate CAS 4075-81-4

Molecular Formula: C4H11NO2

Formula Weight: 116.17

ZSpharmac: Calcium Propionate Supplier

Product Name: Calcium Propionate
CAS No: 4075-81-4
Purity: 99%

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Basic Info

Product Name:Calcium Propionate
Other Names:Calciumpropanoate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystals or Crystalline Powder
EINECS No.:223-795-8
Storage:Store Below +30°C.
Provide:Calcium Propionate MSDS;
Calcium Propionate COA

What is Calcium Propionate?

Calcium Propionate is a commonly used food additive and preservative. Its chemical formula is C6H10CaO4 or Ca(C3H5O2)2, and its molecular weight is 186.18 g/mol. It is composed of calcium salt of propionic acid and is in the form of white crystalline particles or crystalline powder. It has a slight propionic acid smell or is almost odorless. It is hygroscopic and easily soluble in water. The aqueous solution is weakly alkaline and slightly soluble in methanol and ethanol. , insoluble in organic solvents such as benzene or acetone. At higher temperatures, such as about 120°C, calcium propionate will lose crystal water; it will undergo a phase change at 200-210°C; and it will decompose into calcium carbonate at 330-340°C.

As a food antifungal agent, calcium propionate is mainly used in bread, pastries, biscuits, cheese and other baked products to inhibit the growth of mold and certain bacteria and extend the shelf life of food. It is relatively safe for the human body because calcium propionate is an intermediate product of normal metabolism in animals and humans and is easily processed and excreted by the body. Calcium propionate has a weaker antibacterial effect than some other preservatives, such as sorbic acid, but is stronger than acetic acid (acetic acid). It has a good inhibitory effect on Aspergillus niger and some Bacillus, but has little effect on yeast. .

In addition, calcium propionate has other applications, such as in agriculture as a feed additive and as a preservative in cosmetics and personal care products.

Calcium Propionate Property

Melting point 300 °C
density 1.41[at 20℃]
vapor pressure 0-399Pa at 20-23℃
storage temp. Store below +30°C.
solubility water: soluble1g/10 mL, clear, colorless
form Crystals or Crystalline Powder
color White
PH9.2 (200g/l, H2O, 20℃)(IUCLID)
Odorat 100.00?%. bland mild propionic acid
Water Solubility 1 g/10 mL


Calcium Propionate Uses

1. Food preservation
Main uses: Calcium Propionate is one of the most common preservatives in the food industry and is widely used in bread, cakes, biscuits, pies, cheese, pickled products and various baked and cereal products. It inhibits the growth of mold and certain bacteria by releasing propionic acid, and is particularly effective at preventing mold growth, thus extending the shelf life of food and maintaining freshness.

Mechanism of action: Calcium propionate slowly releases free propionic acid in a humid environment, lowering the pH value of food and creating an environment that is not conducive to the growth of microorganisms. It especially has an inhibitory effect on many molds and bacteria, while affecting the taste and texture of the food itself. Less affected.

2. Feed additives
Application: In animal husbandry, Calcium Propionate can be used as a preservative and antifungal agent in animal feed, especially during the preservation process of wet feed and silage. It can prevent feed spoilage, reduce nutrient loss, and protect animal health.

3. Agriculture and Horticulture
Function: In horticulture and agricultural production, Calcium Propionate can be used as a seed treatment agent to prevent mildew of seeds during storage and improve the germination rate of seeds. In addition, it can also act as a plant growth regulator, positively affecting the growth and development of certain crops.

4. Cosmetics and personal care products
Usage: In some cosmetics and personal care products, Calcium Propionate is used as a preservative, which can effectively inhibit the growth of bacteria and mold and maintain product stability and safety. It is commonly found in soaps, shampoos, conditioners and skin creams, etc. in the product.

5. Pharmaceutical field
Potential applications: The application of Calcium Propionate in the medical field is still in the research stage. Its antibacterial properties may make it an ingredient in topical antibacterial ointments or preparations for the treatment of skin infections or other medical purposes, but the actual application requires further research and verification.

Prominent Applications of Calcium Propionate in Cosmetics

1. Mild anti-corrosion properties
As a relatively mild preservative, Calcium Propionate is less irritating to the skin than some traditional preservatives (such as parabens) and is suitable for sensitive skin. In cosmetic products seeking mild, hypoallergenic formulas, calcium propionate can be used as an alternative preservative option to help reduce the risk of skin irritation.

2. Anti-mildew effect
The anti-mold ability of calcium propionate is a highlight in cosmetics. It is especially suitable for products containing high moisture, such as lotions, creams, gels, etc. It can effectively prevent the growth of mold during the storage process of these products. Extend product shelf life. This is crucial to ensure the hygienic safety and product quality of cosmetics.

3. pH adjustment effect
The addition of Calcium Propionate can slightly affect the pH value of cosmetics and help maintain the stability of the product system. In some formulations, it can indirectly enhance the preservative effect by adjusting the pH value, because microorganisms have difficulty surviving in an inappropriate pH environment.

4. Compatibility
In cosmetic formulations, Calcium Propionate has good compatibility with other raw materials and is easy to mix without negatively affecting the color, aroma or texture of the product. It is suitable for a variety of cosmetic types, including but not limited to skin creams, facial cleansers, Shower gel, hair care products, etc.

5. The appeal of natural sources
As consumers’ preference for natural and organic products increases, calcium propionate, as a calcium salt derived from natural propionic acid, is more easily accepted as a more “natural” choice than fully synthetic preservatives, in line with the clean label trend , increasing the market appeal of the product.


National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 19999, Calcium propionate. Retrieved May 16, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Calcium-propionate.

As a company specializing in the production and supply of Calcium Propionate raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the Calcium Propionate raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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