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Calcium Glycerophosphate CAS 27214-00-2

Molecular Formula: C3H7CaO6P

Formula Weight: 210.14

ZSpharmac: Calcium Glycerophosphate Raw Material Supplier

Product Name: Calcium Glycerophosphate
CAS No: 27214-00-2
Purity: 99%

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Basic Info

Product Name:Calcium Glycerophosphate
Other Names:Glycerophosphoric Acid Calcium Salt
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Almost White Powder to Crystal
EINECS No.:248-328-5
Storage:Room Temperature
Provide:Calcium Glycerophosphate MSDS;
Calcium Glycerophosphate COA

What is Calcium Glycerophosphate?

Glycerol calcium phosphate is extensively used in medication, food, tooth paste and also other industries. It can be made use of as a calcium supplement in food; in medicine, it plays the organic and also physiological functions of calcium, has the function of boosting tissue cells as well as creating bone cells, as well as likewise plays the role of calcium glycerophosphate metabolism, and has the feature of supplementing calcium. The duty of mind vitality. As early as 1960, calcium glycerophosphate was discovered to have anti-bacterial and anti-caries impacts. Via study, it has actually been discovered that it can increase the calcium and phosphorus web content in tooth enamel, inhibit the demineralization of tooth enamel, as well as enhance the remineralization of tooth enamel. Calcium glycerophosphate can alter the level of acidity and also alkalinity of the tooth enamel surface and enhance its acid resistance. The advantages of calcium glycerophosphate are self-evident, yet currently it is not widely utilized in my country’s oral treatment products sector. Calcium glycerophosphate is an outstanding additive for oral products, specifically appropriate for calcium-supplementing tooth paste and also chewing gum tissue. It is additionally an anti-caries representative. An excellent resources for additives, it can be used in youngsters’s toothpaste to promote tooth development and also calcium strengthening. Via the solution experiments of numerous items, the addition of calcium glycerol phosphate, taking note of the features of calcium glycerol phosphate, has no apparent distinction in the security and other high quality indications of a lot of oral care products compared with those without addition, and also can give full play to the residential or commercial properties of calcium glycerol phosphate. Calcium has the ability to avoid caries, acid and remineralize teeth, so it needs to play a higher duty in this field.

Calcium Glycerophosphate Property

Melting point > 170℃
density 1.82-1.855[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. Inert atmosphere,Room Temperature
solubility Sparingly soluble in water, practically insoluble in ethanol (96 per cent).
form powder to crystal
color White to Almost white
Water Solubility faint turbidity


Calcium Glycerophosphate Uses

In medication, it is used to advertise the calcification and also formation of bones and teeth. Food nutritional supplements, food calcium fortifiers, stabilizers. Toothpaste quality glycerol calcium phosphate is utilized as a toothpaste additive in the tooth paste market because of its great clarity, high solubility, and quick dissolution speed. Calcium Glycerophosphate has antibacterial and anti-caries impacts. It can increase the calcium and phosphorus content in tooth enamel, hinder the demineralization of tooth enamel, and also enhance the remineralization of tooth enamel. It can change the level of acidity and also alkalinity of tooth enamel surface area as well as boost its acid resistance. The pH of glycerol calcium phosphate utilized as a toothpaste additive is 1.7 ml/g at a particular concentration. At the same time, in order not to influence the top quality of the tooth paste, the clearness of the calcium phosphate needs to be at least slightly turbid. The approach of counteracting calcium hydroxide and glycerol phosphate is made use of, as well as with ethanol removal, the calcium glycerophosphate fulfills the requirement of 1.7 ml/g, the calcium glycerophosphate web content is 80%, and also the clarity reaches the clear toothpaste quality calcium glycerophosphate.

The functions of Calcium Glycerophosphate in tooth paste are primarily shown in the following facets: ① Control of plaque. ② Protective effect on dentin. ③ Impact on the eco-friendly balance of oral flora. In addition, calcium glycerophosphate can enhance the absorption of fluoride. Adding 0.1% to 0.13% calcium glycerophosphate to toothpaste having SMFP can significantly boost the absorption rate of fluoride by enamel as well as enhance the fluorination effect of enamel versus demineralization.

Calcium Glycerophosphate is an excellent toothpaste additive for avoiding cavities, treating gingivitis and also periodontal condition. As a result of its excellent protective effect in tooth paste, calcium glycerophosphate has actually been preferred by the majority of toothpaste manufacturers. Abroad, such as Unilever, and so on, all create glycerol calcium phosphate tooth paste. Freshly arising national brands in China, such as Naisi, Oqili, and so on, are positive concerning the market scenario of high value-added glycerol calcium phosphate tooth paste. Presently, there are small glycerol calcium phosphate toothpaste suppliers. Production of calcium phosphate toothpaste. According to study, markets such as the USA, Japan, Europe, as well as Asia-Pacific currently pay even more attention to sophisticated, high-additional toothpaste products, as well as are a lot more worried regarding the active ingredients in tooth paste. All these show that the market for glycerol calcium phosphate toothpaste has broad room for development. Additionally, calcium glycerophosphate can also be made use of in mouthwash.

Calcium Glycerophosphate Content Analysis

Precisely weigh concerning 2g of the example that has been dried at 150 ° C for 4 hrs, and liquify it in 100ml of water and 5ml of thin down hydrochloric acid test solution (TS-117). Transfer this remedy right into a 250ml volumetric flask, bring it up to volume with water as well as shake well. Pipette 50.0 ml of this remedy right into an appropriate container and also include 50ml of water. Under mixing (preferably with a magnetic stirrer), drop roughly 30ml of 0.05 mol/LEDTA disodium from the burette, then add 15ml of sodium hydroxide examination option (TS-224) and also 300mg of hydroxynaphthol blue indicator, as well as continue dripping Include in the blue end point. Each ml of 0.05 mol/L disodium EDTA is equivalent to 10.51 mg of calcium glycerophosphate (C3H7CaO6P).

Calcium Glycerophosphate Synthesis

Currently, the major approaches for preparing glycerol calcium phosphate consist of phosphoric acid method, phosphate salt approach, phosphorus oxychloride technique, oil trickling approach, etc. The procedures of these methods are fairly complicated, as well as the filtration process of the target product calcium glycerophosphate is difficult and hard to regulate. Calcium glycerophosphate is obtained by counteracting calcium hydroxide and glycerophosphate with ethanol extraction to stay clear of the purification procedure of calcium glycerophosphate. The reaction equation is as complies with:

About Products:
If you need Calcium Glycerophosphate, a cosmetic raw material, please contact our service staff directly and we will provide you with high-quality products at the best price.
As an experienced Calcium Glycerophosphate manufacturer and supplier, our company, ZSpharmac will provide Calcium Glycerophosphate raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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