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Calcium Gluconate Powder CAS 299-28-5

Molecular Formula: C12H22CaO14

Formula Weight: 430.37

ZSpharmac: Calcium Gluconate Powder Supplier

Product Name: Calcium Gluconate Powder
CAS No: 299-28-5
Purity: 99%

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Basic Info

Product Name:Calcium Gluconate Powder
Other Names:Calcium Gluconate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystals or Crystalline Powder
EINECS No.:206-075-8
Storage:Room Temperature
Provide:Calcium Gluconate Powder MSDS;
Calcium Gluconate Powder COA

What is Calcium Gluconate Powder?

Calcium gluconate is the calcium salt of gluconic acid. It is white crystalline or granular powder with a melting point of 201°C. It is odorless and tasteless.

Calcium Gluconate Powder Property

Melting point 195°C
alpha 10.2 º (c=1, H2O 22 ºC)
Boiling point 400℃[at 101 325 Pa]
density 1.677[at 20℃]
vapor pressure 0.004Pa at 20℃
storage temp. Inert atmosphere,Room Temperature
solubility Sparingly soluble in water, freely soluble in boiling water.
form Crystals or Crystalline Powder
color White
Odorat 100.00?%. odorless
Water Solubility 3.3 g/100mL


Calcium Gluconate Powder Uses

  1.  As a food additive, used as a buffer; healing representative; chelating representative; nutritional supplement. According to the “Sanitary Requirements for the Use of Food Nourishment Fortifiers” (1993) promulgated by the Ministry of Health and wellness of my country, it can be utilized in grains and their items, drinks, and also the dosage is 18-38 grams, kg.
  2.  As a medication, it can minimize capillary permeability, boost thickness, keep typical excitability of nerves and also muscular tissues, reinforce myocardial contractility, and also aid bone formation. It appropriates for allergic diseases, such as urticaria; dermatitis; skin pruritus; call dermatitis, as well as lotion health issues; angioedema as an adjuvant therapy. It is likewise ideal for convulsions and also magnesium poisoning brought on by hypocalcemia. It is additionally utilized to prevent as well as deal with calcium deficiency.
  3. Calcium Gluconate in the Powerful Natural Renewal Complex helps skin effectively protect itself from external stressors and maintain a youthful appearance for longer.

Correct use of Calcium Gluconate Powder

Improper use of it will still cause adverse reactions of varying degrees, such as nausea, fever, vomiting, chills, palpitations, etc. In severe cases, it may also lead to serious consequences such as local tissue necrosis, anaphylactic shock, and acute laryngeal edema, threatening Patient’s life safety.

How can we avoid or reduce the occurrence of adverse reactions?
Choosing the right medication is one of the solutions. At present, Calcium Gluconate Powder is mainly administered in two ways: intravenous injection and intravenous drip. Among them, intravenous drip is often used for large volume infusion, and intravenous bolus is mostly used for small volume liquid injection. Clinical studies have shown that intravenous bolus injection increases the probability of serious adverse reactions.

What could be the reason?
On the one hand, the static push speed is not easy to control, which may cause arrhythmia in patients. On the other hand, intravenous boluses may increase drug extravasation, which may subsequently cause desquamation and tissue necrosis. The focus of reducing the occurrence of adverse reactions is to control the injection speed, dilute the concentration of the drug solution and prolong the administration time.

The intravenous injection speed is relatively fast, and the calcium concentration in the blood suddenly rises. High calcium affects the cardiovascular system and other tissues and organs, and various adverse reactions are prone to occur, such as dizziness, headache, nausea, vomiting, chest tightness, arrhythmia, tachycardia Bradycardia, arrhythmia, etc. In severe cases, ventricular fibrillation and severe atrioventricular block will occur. If not rescued in time, the patient’s life may be endangered.

The speed of intravenous drip injection is controlled at 20-30 drops/minute, the calcium agent enters the blood relatively slowly, and the blood calcium will not suddenly rise in a short period of time, so the adverse reactions are significantly reduced.

On the other hand, during the intravenous injection of calcium gluconate, the general nurse is at the bedside, and can deal with it in time when adverse reactions occur. However, during the intravenous infusion of calcium gluconate, most of the nurses are not around. Once adverse reactions are found, they cannot be corrected and treated in time. .

Therefore, how to choose the usage of Calcium Gluconate Powder in clinical practice should be determined according to the specific situation.

If it is used to supplement calcium, you can choose intravenous infusion.

If it is used to control emergencies such as hypocalcemia spasm and numbness around the mouth of the hands, feet, you can choose to inject calcium gluconate intravenously as soon as possible within a safe range.

Does Calcium Gluconate Powder Cause Allergies?

The calcium ions in Calcium Gluconate Powder shot can boost the permeability of cell membrane layer, boost the thickness of blood vessels, reduce the exudation, and play an anti-allergic result. It is commonly made use of in clinical anti-allergic treatment.

There are many reports regarding anaphylactic shock triggered by Calcium Gluconate Powder shot. These cases additionally advise us:

1. Anti-allergic medications may also create allergic reactions. Be vigilant when utilizing anti-allergic drugs to deal with allergic reactions, as well as make emergency situation preparations for anti-allergic reactions;

2. Carefully inquire about the patient’s allergy background;

3. Purely regulate the signs, contraindications and also drug interactions of drugs to stop adverse responses;

4. For clients with allergies when administering the medicine, professional registered nurses must very closely observe as well as discover abnormalities, stop infusion of the medicine immediately when an allergy happens, change the infusion set, record to the doctor in time, and provide prompt and also efficient rescue.

About Products:
If you need Calcium Gluconate Powder, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Calcium Gluconate Powder, ZSpharmac will provide Calcium Gluconate Powder raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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