Zhishang Chemical

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Zhishang Chemical

Ca Gluconate CAS 299-28-5

Molecular Formula: C12H22CaO14

Formula Weight: 430.37

ZSpharmac: Ca Gluconate Supplier

Product Name: Ca Gluconate
CAS No: 299-28-5
Purity: 99%

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Basic Info

Product Name:Ca Gluconate
Other Names:Calcium gluconate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystals or Crystalline Powder
EINECS No.:206-075-8
Storage:Inert atmosphere,Room Temperature
Provide:Ca Gluconate MSDS;
Ca Gluconate COA

What is Ca Gluconate?

Ca Gluconate is the calcium salt of gluconic acid, the molecular formula is C12H22CaO14 · WATER, the molecular weight is 448.40, the melting point is 201 ℃, it is a white crystal or powder, odorless and unappetizing, soluble in cold water, soluble in hot water, insoluble in anhydrous Ethanol, chloroform or ether. Ca Gluconate is a crucial all-natural calcium. It is clinically taken advantage of as a calcium supplement and likewise a basic material for the manufacturing of numerous other gluconates (zinc gluconate, iron gluconate, and so on) as well as glucono delta-lactone. It is an essential chemical export in my nation. thing. Ca Gluconate is mostly taken advantage of as calcium fortifier in addition to nutrient, obstacle, reinforcing representative and likewise chelating agent for food. Glucose as well as calcium carbonate were mixed with each other, glucose oxidase along with catalase were consisted of, and also calcium gluconate was directly acquired by oxidation at 37 ° C.

Ca Gluconate Property

Melting point 195°C
alpha 10.2 º (c=1, H2O 22 ºC)
storage temp. Inert atmosphere,Room Temperature
solubility Sparingly soluble in water, freely soluble in boiling water.
form Crystals or Crystalline Powder
color White
Water Solubility 3.3 g/100mL


Ca Gluconate Uses

  1. Ca Gluconate1. As a food additive, it is utilized as a barrier; a strengthening representative; a chelating representative; a nutritional supplement. According to the “Sanitary Typical for the Use of Food Nutrition Fortifiers” (1993) promulgated by the Ministry of Health of my nation, it can be used in cereals and also their products, and drinks, and the dose is 18-38 grams and kgs.
    2. As a medicine, it can decrease capillary permeability, boost thickness, maintain regular excitability of nerves and muscular tissues, boost myocardial contractility, and aid bone formation. For allergic problems such as urticaria; eczema; pruritus; get in touch with dermatitis, and also product illness; angioedema as adjunctive therapy. It is also ideal for convulsions and also magnesium poisoning triggered by hypocalcemia. It is also made use of for the avoidance and therapy of calcium deficiency.
  2. As a food calcium fortifier, Ca Gluconate has better absorption result than inorganic calcium. my nation states that it can be utilized in grains and their items, and also the dosage is 18-36g/ kg; in milk beverages as well as alcohol consumption fluids, it is 4.5-9.0 g/kg.
  3. Ca Gluconate is utilized as calcium fortifier, buffer, curing representative, chelating representative.
  4. Ca Gluconate is used in cosmetics as a binder and humectant.

Ca Gluconate Extraction Method

Preparation Method of Ca Gluconate

Report One,
CN202110237029.1 discloses a Ca Gluconate zinc oral solution. Each 1000mL oral solution contains calcium gluconate 60g, zinc gluconate 3g, lysine hydrochloride 10g, solubilizer 6-15g, flavoring agent 0.5-2g, an appropriate amount of hydrogen Sodium oxide adjusts the pH of the solution to 3.8 to 4.5, and the solubilizer is one or a combination of two or more of lactic acid, citric acid and gluconic acid. Furthermore, the calcium-zinc gluconate oral solution also contains the calcium gluconate solubility modifier poloxamer 407, and the proportion of poloxamer 407 in every 1000 mL of the oral solution is less than or equal to 12% (g/v). On the premise of ensuring the dosage of Ca Gluconate, the calcium zinc gluconate oral solution provided by the present invention will not cause the problem of crystal precipitation under lower ambient temperature. In addition, even if the freezing phenomenon occurs at extremely low temperature, as long as the calcium gluconate precipitated after the temperature is recovered can be redissolved, the calcium gluconate in the oral solution is still in a dissolved state.

Report Two,
CN202110413980.8 reported the technical field of Ca Gluconate sodium chloride injection, and disclosed a preparation process of calcium gluconate and sodium chloride injection, the preparation process comprising the following steps: Ca Gluconate and sodium chloride were prepared according to 5:4 The proportion of the solution is weighed and added to the water for injection, heated, boiled and dissolved, and then allowed to cool to obtain a solution, which is placed for later use; the solution is filtered for the first time, and then the solution is concentrated with a nanofiltration membrane or a reverse osmosis membrane. The preparation process of the calcium gluconate and sodium chloride injection, by filtering, decarburizing and fine filtration of the mixed solution of calcium gluconate and sodium chloride, makes the Ca Gluconate sodium chloride injection free of any impurities, Improve the purity of calcium gluconate and sodium chloride injection, and adopt canned sterilization treatment at the same time, so that the storage safety of calcium gluconate and sodium chloride injection is improved, and the ratio of calcium gluconate, sodium chloride and water for injection is suitable , No waste of raw materials, energy saving and material saving, with promotion value.

Report Three.
CN202110738204.5 discloses a Ca Gluconate zinc granule and a preparation method thereof, comprising the following components: calcium gluconate, zinc gluconate, lactic acid, lysine hydrochloride, pH adjuster, sweetener, adhesive and essence And pure water and the content is as follows: calcium gluconate 60g; zinc gluconate 5g; lactic acid 5g; lysine hydrochloride 10g; pH adjuster 5g; sweetener 5g; The Ca Gluconate zinc granules can also change the stability of the solution, avoid the precipitation of crystals when the solution is low temperature, and at the same time add a sweetener inside the solution, which improves the astringency of Ca Gluconate and zinc gluconate. Partame or sucrose reduces the possible carcinogenicity of the solution and the problem of excessive sugar caused by sucrose, while the fructose or maltose used has a good taste and will not cause the problem of excessive sugar, and the process is simple and no preservatives are used to ensure medication. safety.

About Products:
If you need Calcium gluconate, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Calcium gluconate manufacturer and supplier, ZSpharmac will provide Calcium gluconate raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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