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BOC-Glycine CAS 4530-20-5

Molecular Formula: C7H13NO4

Formula Weight: 175.18

ZSpharmac: BOC-Glycine Cosmetic Raw Material Suppliers

Product Name: BOC-Glycine
CAS No: 4530-20-5
Purity: 99%

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Basic Info

Product Name:BOC-Glycine
Other Names:Glutamine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Powder
EINECS No.:224-864-5
Storage:Room Temperature
Provide:BOC-Glycine MSDS;
BOC-Glycine COA

What is BOC-Glycine?

Boc-glycine is generally used in peptide synthesis and is mainly made use of in a selection of drugs as well as biotechnology applications. Glycine has a large range of uses and also functions. Utilizing Boc as a safety team to shield glycine is a crucial intermediate raw material for various medications and also biotechnology.

BOC-Glycine Property

Melting point 86-89 °C(lit.)
Boiling point 306.47°C (rough estimate)
density 1.2843 (rough estimate)
refractive index 1.4353 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Powder
color White to off-white
Water Solubility soluble


BOC-Glycine Uses

BOC-Glycine is a non-essential amino acid for the human body. Glycine is an amino acid with the most basic framework in the amino acid collection as well as is non-essential to the body. It has both acidic and also alkaline functional teams in the molecule. It is ionizable in water and also has solid hydrophilicity. It is a polar amino acid as well as is soluble in polar materials. Solvent, but it is difficult to dissolve in non-polar solvents and has a high boiling point and melting point.

BOC-Glycine can be used to deal with myasthenia gravis and also progressive muscular tissue degeneration; deal with hyperlipidemia and also chronic enteritis (often combined with antacids); integrated with pain killers can decrease gastric inflammation; treat hyperlipidemia in youngsters Acidemia; as a nitrogen source to generate non-essential amino acids, contributed to mixed amino acid shot; likewise made use of as a solvent to get rid of carbon dioxide in the fertilizer market; and utilized as a buffer for the preparation of tissue society media, copper, Examining of silver and gold, made use of medicinally to deal with myasthenia gravis as well as modern muscle degeneration, hyperacidity, persistent enteritis, hyperprolinemia in kids and various other illness; made use of in pesticide manufacturing to synthesize pyrethroid pesticides The intermediate glycine ethyl ester hydrochloride can also be used to manufacture the fungicide iprodione and the herbicide strong glyphosate. As a result, it can be used in the synthesis of healthy proteins and also peptides, and is commonly used in pharmaceutical biochemistry, food, cosmetics, and so on. The product is being manufactured.

To summarize, BOC-Glycine has a wide range of uses and functions. In the existing innovation, Boc is utilized as a safety team to secure glycine, which is an important intermediate resources for different medicines as well as biotechnology. Nevertheless, the existing techniques for preparing Boc-Glycine The methods all have certain defects as well as restrictions, making the production not environmentally friendly and risk-free, with reduced returns, and also very easy to produce impurities. The succeeding filtration procedure is taxing as well as laborious, which boosts production costs.

BOC-Glycine Preparation Process

A technique for preparing Boc-glycine, identified because the actions are as complies with:
( 1) Mix L-glycine as well as sodium bicarbonate solution;
( 2) Include (Boc) 2O several times in batches to respond;
( 3) Extraction to remove impurities;
( 4) Adjust to acidity as well as execute secondary extraction;
( 5) Integrate the organic layers, wash till neutral, and also completely dry;
( 6) Condensation as well as filtering to obtain Boc-glycine.

Even more, in (1 ), L-glycine is blended with sodium bicarbonate option, and the certain actions are to add sodium bicarbonate until L-glycine is liquified in water, and also the pH is ≥ 10.

Further, symphonious (3 ), the pollutants are removed as well as removed. The certain actions are to add n-hexane to extract the pollutants numerous times as well as eliminate the organic layer having the impurities.

Better, in (4 ), the acidic second removal is carried out. The specific steps are to add hydrochloric acid service, adapt to acidic pH=1 ~ 3, and after that add dioxane for numerous extractions.

Further, the organic layers in (5) are integrated, washed up until neutral, as well as dried. It is much better to clean with salt water till neutral, and the drying time is managed at 10 to 14 hours.

Additionally, the particular actions of formation and also purification in (6) include adding n-hexane for condensation and also purification to acquire Boc-glycine.

The Advantages of This Study Are as Follows

This study is suitable for inexpensive production of Boc-glycine under straightforward conditions. This research study utilizes safe and non-hazardous (Boc) 2O as a safety reagent. By changing the alkaline conditions, the target compound is manufactured in one step by controlling the amount of materials and the feeding technique.

Using the approach offered in this study to generate Boc-glycine, the return reaches more than 90%, which is greatly boosted compared with previous methods;
The produced items are easy to manage and also have exceptionally low contamination content. The pureness of Boc-glycine can get to greater than 99%. As a result of the straightforward reaction problems, the raw materials used are secure and also eco-friendly, and also are extremely pleasant to the manufacturing environment and also workers;

The price is low, the technique is basic, the procedure is risk-free, the air pollution is little, the return is high, and it is easy to realize commercial production;

Offers a brand-new approach for commercial manufacturing of Boc-glycine.

About Products:
If you need BOC-Glycine, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
Our company, as an experienced BOC-Glycine manufacturer and supplier, ZSpharmac will provide BOC-Glycine raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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