Zhishang Chemical

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Bisabol CAS 515-69-5

Molecular Formula: C15H26O

Formula Weight: 222.37

ZSpharmac: Bisabol Cosmetics Supplier

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Product Name: Bisabol
CAS No: 515-69-5
Purity: 99%

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Basic Info

Product Name:Bisabol
Other Names:Alpha-Bisabolol
CAS:515-69-5
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Liquid
EINECS No.:208-205-9
Storage:Refrigerator
Provide:Bisabol MSDS;
Bisabol COA

What is Bisabol?

Bisabolol, also known as sweet bisabolol and parsnip root alcohol, is a common sesquiterpene compound found in nature. It exists in two forms: α and β. With a molecular formula of C15H26O, it is primarily present in chamomile essential oil, poplar essential oil, and certain essential oils from the Asteria and sage genera. Alpha-bisabolol is known for its healing properties such as ulcer treatment and gallstone dissolution, as well as its analgesic, anti-inflammatory, and antibacterial effects. Recent studies have also revealed additional biological activities of α-bisabolol, including anti-mutagenic properties, inhibition of genetic damage, and skin lightening effects.

Bisabol Property

Melting point 25°C
Boiling point 154-156°C
density 0.93 g/mL at 20 °C(lit.)
refractive index n20/D 1.496
Fp 135°C
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
pka15.04±0.29(Predicted)
form Liquid
color Clear Colourless
Odorat 100.00 %. mild floral peppery balsamic clean
Odor Typefloral
Water Solubility Soluble in alcohol, natural, mineral and synthetic oils. Insoluble in water.

Bisabol Uses

1. Natural bisabolol has strong anti-inflammatory and antispasmodic effects, being twice as effective as the synthetic version. It can reduce the release of leukotrienes LTB4 and interleukin IL-1α, preventing and inhibiting inflammation caused by various irritants.

2. Bisabolol soothes irritation, relieves pain, and promotes skin repair. It is beneficial for allergic skin or children’s skincare, protecting the skin from daily stress and accelerating the healing process.

3. With sedative and anti-sweating properties, bisabolol is commonly used in sunscreen products and ointments for treating sunburn.

4. It possesses broad-spectrum antibacterial properties, making it a useful ingredient in toothpaste and mouthwash to reduce plaque, gum allergies, and bad breath.

5. Bisabolol has a light and pleasant aroma, serving as a stable fragrance fixative in flavors and fragrances.

6. Known for its high permeability, bisabolol is effective in treating skin diseases like acne due to its superior penetration ability.

7. Bisabolol exhibits excellent stability, making it ideal for use in cosmetics without color changes or leakage from containers during long-term storage.

Bisabol Application in Skin Care Products

Bisabolol is known for its anti-inflammatory properties, as it can effectively inhibit the production of peroxidase, which is the main substance that causes inflammation in the body. This makes bisabolol effective in both acute and chronic inflammation. Studies on a three-dimensional skin model have shown that bisabolol can reduce the release of leukotrienes LTB4 and interleukin IL-1α, thereby alleviating inflammation and redness in various animal models. It has been shown to reduce paw edema in rats caused by chemical factors, decrease erythema from UV exposure in guinea pigs, and prevent skin irritation caused by certain chemicals. However, bisabolol does not have an inhibitory effect on prostaglandin PGE2.

Research conducted at the University of Florence in Italy has also revealed that bisabolol, extracted from African myrrh, has analgesic properties. Animal experiments have shown that sesquiterpenes found in myrrh have strong analgesic effects. Furthermore, studies on myrrh extracts have demonstrated that the analgesic effect is enhanced when the volatile oil is combined with an alcohol extract of myrrh.

Additionally, myrrh has been found to have blood-activating properties. Various forms of myrrh, including processed products, have shown significant effects in reducing swelling caused by trauma in animal models. Raw myrrh has a stronger blood-activating effect compared to processed forms, which may be attributed to the decrease in volatile oil Bisabol content after processing.

Overall, bisabolol, derived from myrrh, offers a range of benefits including anti-inflammatory, analgesic, and blood-activating effects, making it a valuable ingredient in skincare and medicinal products.

Contact Us

About Products:
If you need Bisabol, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
Our company, as an experienced Bisabol manufacturer and supplier, ZSpharmac will provide Bisabol raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Bisabol Quotation