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Zhishang Chemical

Bha Butylated Hydroxyanisole CAS 25013-16-5

Molecular Formula: C11H16O2

Formula Weight: 180.24354

ZSpharmac: Bha Butylated Hydroxyanisole Supplement

Product Name: Bha Butylated Hydroxyanisole
CAS No: 25013-16-5
Purity: 99%

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Basic Info

Product Name:Bha Butylated Hydroxyanisole
Other Names:Butylated Hydroxyanisole
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystalline Crystals
EINECS No.:246-563-8
Provide:Bha Butylated Hydroxyanisole MSDS;
Bha Butylated Hydroxyanisole COA

What is Bha Butylated Hydroxyanisole?

Tert-Butyl-4-Hydroxyanisole (English: Butylated hydroxyanisole, BHA) is an antioxidant came from 2 isomers, 2-tert-butyl-4-hydroxyanisole along with 3-tert-butyl-4-hydroxyanisole. combination. It is manufactured by responding p-hydroxyanisole with tert-butanol (or isobutylene), or 2-tert-butyl hydroquinone with dimethyl sulfate. The major uses BHA are as anti-oxidants as well as chemicals in food (consisting of animal food), food packaging, cosmetics as well as oil products. In addition, it is also utilized as an anti-oxidant for medicines such as isotretinoin along with simvastatin.

Bha Butylated Hydroxyanisole Property

Melting point 

58-60 °C(lit.)

Boiling point 



0.9976 (rough estimate)

vapor density 

6.2 (vs air)

refractive index 

1.4910 (estimate)


>230 °F

storage temp. 



Practically insoluble in water; soluble in methanol; freely soluble in ≥50% aqueous ethanol, propylene glycol, chloroform, ether, hexane, cottonseed oil, peanut oil, soybean oil, glyceryl monooleate, and lard, and in solutions of alkali hydroxides.


Crystalline Flakes or Crystals


White to pale yellow

Water Solubility 

<0.1 g/100 mL at 18.5 ºC



Bha Butylated Hydroxyanisole Uses

  1. Tert-Butyl-4-Hydroxyanisole anti-oxidant, the antioxidant effect of 3-BHA included in food is 1.5-2 times stronger than that of 2-BHA, yet the combination of the two has a specific collaborating effect, therefore, a combination containing a high proportion of 3-BHA, its efficacy Nearly comparable to pure 3-BHA. can connect with the peroxide created in the oxidation procedure of oil, so as to cut off the domino effect of automatic oxidation of oil and prevent oil from continuing to oxidize. is mixed with various other antioxidants and synergists such as citric acid, and also its antioxidant impact is much more obvious. Along with the antioxidant effect, additionally has a relatively solid anti-bacterial power and also has an antifungal effect. As a food additive, it is used as an anti-oxidant for oils such as fats as well as oils, lard, salted fish and also shellfish, dried out fish as well as shellfish products, pretzels, potato chips, instantaneous noodles, and also fried snacks. Also used as feed ingredients and also gas additives. 3-tert-Butyl-4-hydroxyanisole (2-BHA) is likewise used as a biochemical reagent.
  2. Tert-Butyl-4-Hydroxyanisole is an oil-soluble antioxidant widely utilized in your home and also abroad. The antioxidant capability of 3-BHA is 1.5 to 2 times that of 2-BHA, as well as the combination of the two has a particular collaborating result. Combined with other oxidants or made use of with synergist citric acid, the antioxidant result is more considerable. my country stipulates that it can be used in edible oils and also fats, fried foods, biscuits, immediate noodles, quick-cooked rice, tinned nuts, dried fish items and also cured meat items, with a maximum dose of 0.2 g/kg (the optimum dosage is calculated as fat); mixed with BHT When used, the overall amount ought to not surpass 0.2 g/kg; when combined with BHT and also PG, the total quantity of BHA and also BHT need to not go beyond 0.1 g/kg, and PG must not exceed 0.05 g/kg. This product likewise has a fairly strong antibacterial impact as well as works versus a lot of bacteria and mold and mildews.
  3. Tert-Butyl-4-Hydroxyanisole functions as a feed antioxidant as well as likewise has anti-bacterial homes. BHA dosage of 250mg/kg can prevent the manufacturing of aflatoxin, and also 200mg/kg BHA can entirely inhibit the development of spores such as harmful enzymes and also Aspergillus niger in food and feed.
  4. Tert-Butyl-4-Hydroxyanisole is a fat-soluble antioxidant appropriate for fatty and fatty foods. Due to its thermal security, it can be made use of in frying or roasting conditions. In addition, butylated hydroxyanisole has strong antioxidant effect on physical fat, but bad antioxidant impact on unsaturated veggie fat. Butylated hydroxyanisole can maintain the pigment of raw beef as well as inhibit the oxidation of ester compounds.

Production Method of Bha Butylated Hydroxyanisole

(1) Preparation of intermediate p-hydroxyanisole. Can hydroquinone be raw material to be acquired with alkylation, here gives para-aminoanisole as raw material to get synthesis technique:
P-aminoanisole and sodium nitrite (molar proportion 1:1:15) were included in the reaction pot, as well as diazotized in the existence of sulfuric acid. After the response was completed, the mixture was kept cozy as well as filteringed system, as well as the filtrate was gradually added to hot water for hydrolysis. The generated p-hydroxyanisole is right away removed with vapor, and also removed with natural solvent benzene after condensation. The solvent was eliminated by focus as well as distillation to obtain the product with an average return of 84.7%.
( 2) Tert-Butyl-4-Hydroxyanisole was manufactured. The solvent benzene, tert-butanol and also p-hydroxyanisole were added to the reaction pot for home heating and also dissolving in turn, then phosphoric acid or sulfuric acid as catalyst was included, and the reaction was refluxed under vigorous stirring at 80 ° C. After the response is completed, the product is discharged as well as entrusted to mean stratification. The organic stage was cleaned with 10% salt hydroxide service and water up until nonpartisanship. The solvent is gotten rid of by purification, and after that recrystallized from ethanol to acquire the completed item.

Limit of Bha Butylated Hydroxyanisole used in One Product

The optimum quantity of Tert-Butyl-4-Hydroxyanisole needs to not exceed 0.2 g/kg on a fat basis. When the dosage is 0.02%, the antioxidant impact is 10% more than that of 0.01%, and also when the dose exceeds 0.02%, the antioxidant result reduces. When blended with BHT and also propionone gallate, the total amount of antioxidants will not surpass 0.1 g/kg.

The dose of in animal oil is 0.001 ~ 0.01%; Grease: 0.002 ~ 0.02%; Baked food: 0.01 ~ 0.04%; Cereal food: 0.005 ~ 0.02%; Soymilk powder: 0.001%; Fine-tuned oil: 0.01 ~ 0.1; Candy, The amount of eating gum tissue base can reach 0.1%.

When utilized on product packaging products, it can be smeared on the inside of the product packaging materials, or loaded with the heavy steam of anti-oxidants in the packaging bags, or sprayed on the packaging paper, and also the dosage is 0.02%-0.1%.

When Tert-Butyl-4-Hydroxyanisole is utilized as an antioxidant in cosmetics, it can have an antioxidant effect on acids, hydroquinone, methionine, as well as lecithin.

Is utilized in mix with synergists such as citric acid, tartaric acid, ascorbic acid and also phosphoric acid, and has a substantial synergistic impact. is thermally stable, not quickly ruined under weak alkaline conditions, and does not color with steel ions. additionally has solid antibacterial effect on Staphylococcus aureus, Aspergillus parasiticus spores, Aspergillus flavus, etc. can also be utilized as an antioxidant in feed.
Along with the antioxidant effect, additionally has a solid anti-bacterial result. As a food anti-oxidant, it can hinder the oxidation of oily food as well as postpone the moment when the food starts to spoil. When used as an antioxidant in cosmetics, it can have an antioxidant effect on acids, hydroquinone, methionine amino acids, lecithin as well as sulfurized dipropionic acid. It can additionally be utilized as an antioxidant in feed.

my country’s “Hygienic Standard for making use of Food Additives” (GB2760-1996) states that butylated hydroxyanisole can be used in edible oils and also fats, fried foods, dried fish items, biscuits, instantaneous noodles, quick-cooked rice, tinned nuts, healed meat products, For morning meal grains, the optimum dose is 0.2 g/kg. When butylated hydroxyanisole is mixed with dibutylhydroxytoluene as well as propyl gallate, the total quantity of butylated hydroxyanisole and dibutylated hydroxytoluene will not exceed 0.1 g/kg, as well as propyl gallate will not surpass 0.05 g/kg kg (the amount used is determined as fat). Furthermore, it can also be utilized for gum candy components.

About Products:
If you need Bha Butylated Hydroxyanisole, a cosmetic raw material, please contact our service staff directly, we will provide you with quality products at the best price.
Our company, as an experienced Bha Butylated Hydroxyanisole manufacturer and supplier, ZSpharmac will provide Bha Butylated Hydroxyanisole raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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