Zhishang Chemical

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Zhishang Chemical

Betaine CAS 107-43-7

Molecular Formula:C5H11NO2

Formula Weight:117.15

Purity: 99%

Product Name: Betaine
CAS No: 107-43-7

Basic Info

Product Name:Betaine
Place of Origin:Shandong, China
Brand Name:Zhishang Chemical
Type:Zwitterionic surfactant
Appearance:Crystalline Solid
EINECS No.:203-490-6
Storage:Cool Dry Place
Provide:Betaine MSDS;
Betaine COA


Product Categories:

Zwitterionic surfactant; Traditional Chinese medicine reference substance; Standard; Reference substance, standard substance; Analytical standard; Pharmaceutical raw materials; Enzymes and coenzymes; Organic acids; Plant extracts; Reference substance; Food additives; Plant hormones and nucleic acids; Intermediate – organic synthetic intermediate; Nutrition fortifier; Analytical reagent standard; Standard extract; intermediate; Biochemical reagents – plant hormones and nucleic acids; Chemical products – Organic Chemical; vitamin; Organic chemical raw materials; Material intermediates and additives; Flavors and fragrances; Standard reference;

  1. Betaine Extraction method. The mother liquor of beet sugar production contains 12% – 15% betaine, which can be recovered directly. Heat 300 parts of mother liquor to 50 ℃, add 80 parts of calcium chloride, stir for a certain time and filter while hot. The filtrate is acidified with hydrochloric acid, cooled to 20-30 ℃ for crystallization, separated and dried to obtain about 30 parts of betaine.
  2. Betaine Synthetic method. It is obtained by quaternization of chloroacetic acid and trimethylamine. 195 parts of 48.6% chloroacetic acid aqueous solution are neutralized with 16% sodium hydroxide solution to form sodium chloroacetate solution, then mixed with 360 parts of 16.4% trimethylamine solution, ventilated at 50 ℃ for 1 hour and ventilated at 80 ℃ for another hour. After dilution, the reactants were adsorbed by ionic resin and eluted with ammonia to obtain betaine solution. After vacuum concentration and crystallization, the finished product is obtained.
Chemical Properties:

Crystalline Solid

Melting point 310 °C (dec.)
Boiling point 218.95°C (rough estimate)
density 1.00 g/mL at 20 °C
refractive index 1.4206 (estimate)
storage temp. 2-8°C
solubility methanol: 0.1 g/mL, clear
pka1.83(at 0℃)



Betaine  Betaine is a quaternary ammonium alkaloid. Anhydrous betaine is a new fine chemical, which can be widely used in food, medicine, daily chemical, printing and dyeing, chemical and other fields. Anhydrous betaine is an efficient and high-quality nutritional additive. Pharmaceutical grade betaine can be used in medicine, cosmetics, food, fruit juice industry and dental materials. In addition, betaine can also be used in fermentation industry. Anhydrous betaine has the functions of brightening eyes, anti fatty liver, protecting kidney, treating cardiovascular diseases such as atherosclerosis and so on. It is used as health food.

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Betaine Quotation