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Bergenin CAS 477-90-7

Molecular Formula: C14H16O9

Formula Weight: 328.27

ZSpharmac: Bergenin Supplier

Product Name: Bergenin
CAS No: 477-90-7
Purity: 99%

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Basic Info

Product Name:Bergenin
Other Names:Bengenin
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Neat
EINECS No.:803-760-9
Provide:Bergenin MSDS;
Bergenin COA

What is Bergenin?

Rock cabbage is also called plain cabbage, rock wall veggie, red rock seven, as well as rock 7. It was first published in “Plant Labels and Facts of Plant kingdoms”. It is the rhizome or whole plant of Bergenia purpurascens (Hook.f.etThoms.) Engl. or B. crassifolia (L.) Fritsch, a plant of Saxifrageaceae. The previous is distributed in Yunnan, Sichuan, Tibet and also other districts; the latter is distributed in the Altai Mountains of Xinjiang. It is a typical medicinal product of the Naxi people.

The preference is bitter, astringent, flat in nature. Feature k expectorant as well as antitussive, astringent to stop hemorrhaging, antidiarrheal. Signs for coughing, hematemesis, hemoptysis, hematochezia, dysfunctional uterine blood loss, distressing blood loss, looseness of the bowels, dysentery, stranguria, red as well as white leucorrhea, and so on. For example, taking this product as a product with Chinese organic medication, or taking rock cabbage slices can cure chronic respiratory disease; it can be utilized to treat consumption and coughing when combined with Baibu, Lily, Radix Asparagus, as well as Ophiopogon japonicus. On top of that, this product is also used for rheumatic pain and also contusions, as well as has the result of relaxing tendons and also triggering securities. It is likewise utilized as a tonic and also strong medicine to deal with physical deficiency, wooziness and various other syndromes. It can still be used on the surface to treat yellow water sores. Decoction, 6 ~ 12g.

Bergenin Property

Melting point 237-240 °C(lit.)
alpha D18 -37.7° (c = 1.96 in ethanol); D24 -45.3° (c = 0.51 for anhydr in water)
Boiling point 386.03°C (rough estimate)
density 1.3901 (rough estimate)
refractive index 1.6550 (estimate)
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly)
form neat
color White to Off-White


Bergenin Efficacy

Bergenin is an energetic component of rock cabbage, has the result of antitussive and expectorant, and also is a “special result” drug for the therapy of persistent bronchitis, emphysema, bronchial asthma as well as other respiratory system diseases. A selection of substance prep work utilizing Bergenin as resources have actually been utilized in the clinical therapy of persistent respiratory disease and persistent respiratory disease. As an example, the substance rock cabbage tablets established by Yunnan Baiyao Team and the Bai Ling substance rock cabbage tablets established by Guizhou Bailing Pharmaceutical Co., Ltd. are all Chinese patent medicines for the therapy of chronic bronchitis. On top of that, Bergenin also has the feature of scavenging cost-free radicals and also inhibiting lipid peroxidation without harmful side effects. This impact simply fits the prominent skin treatment concepts such as anti-oxidation and scavenging complimentary radicals suggested by the cosmetics industry over the last few years. For that reason, lots of cosmetics suppliers include rock cabbage as an antioxidant resources to skin care items.

The Preparation Method of Bergenin

A compound Bergenin tablet and a preparation method thereof. The main ingredients are petracenin and chlorpheniramine maleate in legal quantities, and the ratio of auxiliary materials is: 8-25% starch, 20-40% dextrin, microcrystalline Cellulose 0-30%, hypromellose 0-10%, carboxymethyl starch sodium 10-20%, and the balance is lubricant.

By changing the formula of excipients in the original production process, the stability of the compound Bergenin tablets is effectively improved, and the quality problems of the compound Bergenin tablets that are easy to crack and the content is unstable during storage are solved. The compound Bergenin tablet prepared by the invention has a smooth surface and stable performance, is suitable for large-scale production, and the product quality meets the requirements of national drug standards.

Pharmacological Effects of Bergenin

Bergenin is an isocoumarin compound extracted and refined from Xinjiang Saxifrageaceae plant Rock Cabbage. It has good antitussive and expectorant effects on chronic bronchitis. Chlorpheniramine maleate has a strong histamine H1 receptor blocking effect, can relieve other respiratory symptoms caused by allergies, and also has a mild inhibitory effect on the central nervous system.

About Products:
If you need Bergenin as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Bergenin manufacturer and supplier, ZSpharmac will provide Bergenin raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Bergenin Quotation