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Zhishang Chemical

Benzyl Benzoate Usp CAS 120-51-4

Molecular Formula: C14H12O2

Formula Weight: 212.24

ZSpharmac: Benzyl Benzoate Usp Supplement

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Product Name: Benzyl Benzoate Usp
CAS No: 120-51-4
Purity: 99%

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Basic Info

Product Name:Benzyl Benzoate Usp
Other Names:Benzyl Benzoate
CAS:120-51-4
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless Liquid
EINECS No.:204-402-9
Storage:2-8°C
Provide:Benzyl Benzoate Usp MSDS;
Benzyl Benzoate Usp COA

What is Benzyl Benzoate Usp?

Benzyl Benzoate Usp is a colorless or light yellow thick transparent liquid under basic conditions. It will develop into a white solid when kept for a long time listed below 17 ° C. High-purity benzyl benzoate has a faint flower scent.

Benzyl Benzoate Usp Properties:

Melting point 17-20 °C (lit.)
Boiling point 323-324 °C (lit.)
density 1.118 g/mL at 20 °C (lit.)
vapor pressure 1 mm Hg ( 125 °C)
refractive index n20/D 1.568(lit.)
  
Fp 298 °F
storage temp. 2-8°C
solubility Miscible with ethanol, alcohol, chloroform, ether, oils.
form Liquid
color Clear colorless
Water Solubility practically insoluble

 

Benzyl Benzoate Usp Uses

  1. Benzyl Benzoate Usp is made use of as a solvent and also fixative, and also is additionally made use of in perfumery.
  2. Benzyl Benzoate Usp is used as a solvent for musk as well as a fixative for significance, a replacement for camphor, and additionally for the prep work of pertussis medicine, bronchial asthma medicine, etc.
  3. Benzyl Benzoate Usp is a food taste enabled by my nation’s “Hygienic Criteria for using Food Additives”. It is mainly utilized as a fixative for the prep work of strawberry, pineapple, cherry and also other fruit-type edible flavors and red wine flavors. The quantity used in gum is 280mg/kg; 39mg/kg in sweet; 33mg/kg in baked goods; 12mg/kg in chilly beverages; 4.5 mg/kg in soft drinks.
  4. Benzyl Benzoate UspGB 2760-1996 specifies that it is an allowed edible flavor. Utilized as a fixative. Primarily made use of for the preparation of berry tastes such as plums as well as cherries.
  5. Benzyl Benzoate Usp Solvent for cellulose acetate, cellulose nitrate and also artificial musk, fixative, plasticizer. Acaricide.

Benzyl Benzoate Usp Production Method

Benzyl Benzoate Usp naturally exists in Peru balsam, tuberose, carnation and turmeric, and is usually produced by chemical synthesis in industry.
Add 7g (0.07mol) of benzyl alcohol to a 100mL round-bottomed flask, add 0.3g (0.013mol) of metal sodium within 30min and dissolve it in it, cool to room temperature and slowly add 45.4g (0.43mol) of benzaldehyde in a 250mL three-neck bottle. The mixture heats up due to the reaction and is cooled with water so that the temperature does not exceed 50-60°C. After about 30 min, when the temperature stopped rising, the reaction was continued for 1 h by heating in a water bath. After the reaction was cooled, 40 mL was used. Wash with water 2 times. The obtained oily substance is subjected to vacuum distillation, firstly, benzyl alcohol, unreacted benzaldehyde and a small amount of water are distilled off, and then the fraction at 184-185°C (2kPa) is collected to obtain about 40g of product.
2C6H5CHO→C6H5COOCH2C6H5
Benzyl alcohol and ethyl benzoate are transesterified in the presence of sodium carbonate. After the reaction is completed, ethanol is first removed by atmospheric distillation, and then benzyl alcohol is removed by reduced pressure distillation. After cooling, it is washed with water, layered, dried, and finally distilled under reduced pressure to obtain the product. C6H5COOCH2CH3+C6H5CH2OH[Na2CO3]→C6H5COOCH2C6H5+CH3CH2OH

Benzyl Benzoate Usp Solution for Skin Problems

Scabies is treated with topical permethrin, Benzyl Benzoate Usp, malathion, or oral ivermectin. Clients must apply 5% permethrin lotion to the whole body, containing the scalp, all folds, groin, navel, outside genitalia, and also skin under the nails, as well as likewise wipe after 12 humans resources. Therapy of the face in grownups with ageless scabies is open to question, yet in babies the facial skin requirement to likewise be dealt with. A 2nd application must be supplied 7 days after the initial treatment, and all impacted family members need to be managed at the same time to prevent routine reinfections. Oral ivermectin is progressively being used as first-line treatment. Extreme break outs call for a second dose of ivermectin (200 µg/ kg body weight) every 2 weeks. Treatment of 2nd bacterial infections as well as also antihistamines might be needed. Cleaning garments as well as sheets at 60 ° will absolutely remove all young fed women termites (an alternative is to keep them in a plastic bag for 48-72 hrs, as termites divided from their human hosts will absolutely die throughout this moment die). It is required to clarify that itching usually remains for numerous weeks after healing and additionally can be partially reduced by non-sedating or sedating antihistamines.

Benzyl Benzoate Usp Toxicological Information

Recognition as well as use: Benzyl Benzoate Usp is a liquid. Made use of as a solvent for cellulose acetate, nitrocellulose as well as man-made musk, replacing camphor compounds in celluloid as well as plastic timber waxes, fragrance fixatives, sweet and also eating periodontal tastes. As an insecticide/miticide, it is used to manage dust mites on carpetings, mattresses, upholstery as well as furnishings. Benzyl Benzoate Usp is made use of as an alternative to the topical therapy of scabies and also has additionally been made use of for the topical therapy of pediculosis (lice problem). It is additionally made use of in vet medication as an acaricide and pediculicide, however is contraindicated in felines. It was utilized in the Vietnam Battle to get rid of and also drive away certain ticks and also termites. Human Research studies: Straight call might create skin inflammation. Direct contact with liquid can irritate eyes, but no damage has actually been reported. There is no proof that topical benzyl benzoate cream has an unfavorable effect on maternity outcomes. Benzyl Benzoate Usp generates estrogenic reactions in cultured human bust cancer cells cell lines. Pet Researches: A 13-week research in rats demonstrated lowered body weight gain and death at 800 mg/kg/day. Signs of neurotoxicity such as incredible, dyspnea, and also sleepiness were kept in mind. There was bleeding around the mouth and nose, and histological damage to the mind, thymus, skeletal muscle mass, and kidneys. Benzyl Benzoate Usp has actually not been examined for carcinogenicity, however its metabolite, benzyl alcohol, has actually been evaluated in rats as well as mice. No evidence of cancer causing activity was discovered in benzyl alcohol. Maternal and fetal toxicity of benzyl benzoate was examined in pregnant rats following daily oral doses of 25 and also 100 mg/kg. The outcomes suggest that benzyl benzoate and its metabolites can be moved to the placenta as well as inevitably right into the fetus. Benzyl Benzoate Usp was checked for mutagenicity and was located to be unfavorable for induction of unexpected ethylene glycol nucleic acid synthesis in rat hepatocytes. The chemical does not damage hormonal agents or create anomalies in animal cells in vitro.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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