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Benzil CAS 134-81-6

Molecular Formula: C14H10O2

Formula Weight: 210.23

ZSpharmac: Benzil Supplement

Product Name: Benzil
CAS No: 134-81-6
Purity: 99%

Basic Info

Product Name:Benzil
Other Names:Benzil, 99%
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Organic Intermediate
Appearance:White Crystal Powder
EINECS No.:205-157-0
Storage:Store Below +30°C.
Provide:Benzil MSDS;
Benzil COA

What is Benzil?

 Benzil is widely used in organic synthesis and pharmaceutical industry as a raw material and intermediate. It can be used for synthesizing pesticides, photosensitizers for UV-curable resins, printing inks for food, etc. It has broad application prospects in the pesticide, pharmaceutical and food industries.

Benzil Properties:

Melting point 94-95 °C(lit.)
Boiling point 346 °C
density 1,521 g/cm3
vapor pressure 1 mm Hg ( 128.4 °C)
refractive index 1.5681 (estimate)
Fp 346-348°C
storage temp. Store below +30°C.
solubility <0.5g/l
form Crystalline Powder
color White
Water Solubility 0.5 g/L (20 ºC)


Benzil Uses

  1. Benzil is used in photosensitizers, intermediates in organic synthesis, and can also be used as adhesives, etc.
  2. Benzil Organic synthesis intermediate, also used in pesticides. The product is promising as a photosensitizer for ultraviolet curable resins (UV resins). Bibenzoyl sensitizes to UV light in a wide range of wavelengths. Benzoin is below 3400A, and benzoin alkyl ether is below 3900A. The dibenzoyl below 4800A can be sensitized in a wide wavelength range, so it can be used for curing thick film resins, which is a feature that was not available in UA resin sensitization before. And there is no smell after curing, so it is suitable for making printing inks for food packaging.
  3. Benzil is used as a pharmaceutical intermediate, a photosensitizer for UV-curable resins, etc.

Benzil Production Method

Condensed by benzaldehyde and sodium cyanide to obtain benzoin (benzoin), and then obtained by nitric acid oxidation. This process is polluted due to the production of nitrous acid gas, and the reaction is intense and requires careful operation. The production reagent bibenzoyl also uses copper acetate or copper sulfate. For example, 4100g of crystalline copper sulfate, 4000g of pyridine and 1600g of water are stirred and heated together, then 1696g of benzoin is added, and the reaction is heated for 2h. The ketone sulfate-pyridine solution was then decanted. The crystals were washed with water and co-heated with 10% hydrochloric acid. After cooling, filter out the crystals to obtain 1450 g of bibenzoyl. This product is obtained by oxidizing benzoin with air or nitric acid. The benzoin and nitric acid (40%) were added to the reaction pot, and the temperature was slowly raised to 110 °C over 4 h, and the reaction was maintained for 1 h. Then it was cooled to below 40°C, filtered and washed with water to obtain the crude biphenoyl. Add water to the crude product, adjust the pH to 12 with 30% sodium hydroxide, heat to 100°C to dissolve, filter after cooling, and wash with water to obtain the finished product. The yield is above 95%.

Preparation method of Benzil

Using benzoin as a raw material to prepare benzophenone, the traditional oxidation methods include: chromate oxidation, nitric acid oxidation, permanganate oxidation, ferric chloride oxidation, copper sulfate oxidation, etc. These oxidation methods are all Using metered oxidant has high cost, large amount of waste residue and serious pollution. It is of great significance to develop a green and efficient catalytic oxidation method to catalyze the oxidation of benzoin to benzoin.

Molecular oxygen is cheap and abundant, and it is very attractive to develop an efficient catalytic system using molecular oxygen as the oxygen source for the selective oxidation of benzoin to benzoin. Journal of Molecular Catalysis A: Chemical (1996, 111, 33-36) reported a method for preparing benzoin by catalyzing oxygen oxidation of benzoin using Co(acac)2 and Fe(acac)3. As an oxidant, the conversion rate of benzoin and the selectivity of benzoin are relatively high, but in the reaction process, it is necessary to add three times the amount of aldehyde or acetal relative to the raw material benzoin, which increases the cost and improves the separation and purification of products. difficulty. Journal of Molecular Catalysis A: Chemical (2001, 165, 283-290) discloses a method for preparing benzoin by catalyzing the oxidation of benzoin with H3+nPMo12-nVnO40 (n=1-4) as an oxidizing agent, The reaction conditions are mild, and by-products such as benzaldehyde, benzoic acid, and benzoic acid esters generated by the cleavage of carbon-carbon bonds make the selectivity of benzophenone low. Catalysis Communications (2010, 11, 684‑688) reported that air was used as an oxidant, and hydrotalcite doped with different metals was used as a catalyst to catalyze the oxidation of benzoin. The reaction conditions were mild and the selectivity of benzophenone was good, but the catalyst preparation steps were cumbersome, long cycle.

A method for directly oxidizing benzoin with molecular oxygen to prepare benzoin, specifically using a compound of bismuth as a catalyst, oxygen or air as an oxidant to oxidize benzoin to prepare benzoin, and the compound of bismuth is less toxic as a catalyst, Oxidant oxygen comes directly from air, with low cost and mild reaction conditions, and has good industrial application prospects.

Add 0.1 mol% (relative to the molar amount of raw material benzoin) bismuth oxide and 0.53 g of benzoin into a 10 ml three-necked flask, add 2 ml of absolute ethanol, introduce oxygen by bubbling, heat up to 80 ° C under stirring, and keep for 6 h . Then cooled to room temperature, sampling was used to compare the gas chromatography retention time of GC-MS and standard substances to characterize the oxidation product. The main product detected by GC-MS was benzophenone, and a small amount of benzaldehyde and benzoic acid, which were retained by gas chromatography. Time comparison results are consistent with GC‑MS, quantified using gas chromatography analysis. The schematic diagram of the reaction is shown in Formula 1, and the corresponding analytical chromatogram is shown in Figure 1. The conversion rate of benzoin is 96%, the selectivity of benzophenone is 94%, and the by-products are mainly a small amount of benzaldehyde and benzoic acid.

Other Applications of Benzil

Benzil are important organic chemical raw materials and are widely used in the synthesis of polymer curing photosensitizers and drugs.

1) prepare a kind of moth-eaten low-density polyethylene cable material, which is made of the following raw materials by weight: low-density polyethylene 46-62, polyethylene terephthalate 24-36, celluloid 18-32, Diphenylethanedione 3-7, Dimethyl fumarate 5-10, Red mud 7-14, Porcelain tailings 9-16, Dimethyl propane carboxylate 6-12, Ash calcium powder 10-15 , dimethyl phthalate 10-15. The invention combines low-density polyethylene, polyethylene terephthalate and celluloid with each other, which obviously improves the heat resistance and weather resistance of the polyethylene cable material. Dimethyl fumarate, dimethyl propane carboxylate, oriental orientalis essential oil, 3-chloropropene and other raw materials can significantly improve the anti-moth-eaten performance of polyethylene cable materials, protect cables from moths, and have good application prospects .

2) Prepare a (±)-1,2-diphenylethylenediamine. Using 1,2-diphenyl ethylenedione dioxime, using one of hydrazine hydrate, formic acid, sodium formate, ammonium formate, ammonium formate-triethylamine system as the hydrogen source, at 20 ℃-100 ℃, using lightning Nickel is used as catalyst, activated carbon is used as co-catalyst, and (±)-1,2-diphenylethylenediamine is obtained by catalytic reduction in polar solvent. The invention has the advantages of simple and extensive raw material sources, low price, safe production process, short process flow, mild reaction conditions, low cost, environmental friendliness and the like, and is very suitable for industrial production.

3) Prepare a photosensitive conductive silver paste, which is composed of the following raw materials in parts by weight: 100-106 high-dispersion conductive silver powder, 0.6-1 triterpene saponin, 12-14, 2, 2, methacrylic resin, 4-trimethyl-1,3-pentanediol monoisobutyrate 20-30, toluene 20-30, titanium nitride 0.1-0.2, diphenyl ethylene glycol 1-2, polyethylene glycol 1-2 , phthalate 2-3, polyvinyl alcohol 0.2-0.4, glass powder 10-15, ceramic powder 2-3, the high-dispersion conductive silver powder of the present invention is that the nano-silver powder is uniformly and densely coated on the polymer The surface of the microspheres can not only reduce the amount of precious metal silver powder and production cost, but also greatly improve the dispersibility and stability of the nano-silver powder.

4) Preparation of a class of 2,3-diphenyl-6-amidoquinoxaline compounds. The preparation method includes the following steps: 1) benzoin condensation reaction of benzaldehyde to generate benzoin; 2) the generated benzoin is oxidized to generate 1,2-diphenylethanedione; 3) 1,2-diphenylethanedione Then cyclization with 4-nitro-o-phenylenediamine generates 2,3-diphenyl-6-nitroquinoxaline; 4) 2,3-diphenyl-6-nitroquinoxaline is reduced Generate 2,3-diphenyl-6-aminoquinoxaline; 5) 2,3-diphenyl-6-aminoquinoxaline reacts with various acid chlorides to generate 2,3-diphenyl-6-amido Quinoxaline compounds.

Company Profile and Company Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Company Culture:

Our Mission
Help China Chemicals to benefit the happiness of human life
Our Vision
Become the most trusted chemical supplier in the world
Our Business Philosophy
Striver – oriented, enrich employees, customer first, deep service, seek development
Our Valuse
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Benzil Quotation