The scientific effectiveness and also security of Xiaoer Soy Qiao Qingre Granules incorporated with azithromycin in the treatment of children with Mycoplasma pneumoniae pneumonia were systematically assessed. Approaches: Computer system browsed Chinese Academic Journals Full-text Data Source (CNKI), VIP Chinese Journals Full-text Data Source (VIP), Wanfang Data, China Biomedical Literary Works Database (CBM), Cochrane Library, PubMed and Web of Science in Chinese as well as English The data source was accumulated from the randomized controlled tests (RCTs) of Xiaoer Chiqiao Qingre Granules incorporated with Azithromycin Bnfin the treatment of youngsters with Mycoplasma pneumoniae pneumonia. Outcomes: A total of 9 RCTs including 1 072 kids were consisted of. The results of Meta-analysis showed that: Xiaoer Chiqiao Qingre Granules combined with azithromycin group could improve the complete effective price [RR= 1.16, 95% CI( 1.05, 1.27), P= 0.003] and shorten the cough loss time [MD= -2.54, 95% CI( -3.44, -1.46), P< 0.000 01], shortening the loss time of pulmonary rales [MD= -2.55, 95% CI( -4.39, -0.70), P= 0.007], antipyretic time [MD= -2.08, 95% CI (-2.84, -1.31), P< 0.000 01], reduced interleukin-6 degree [MD= -7.88, 95% CI (-12.33, -3.43), P= 0.000 5], lower the unfavorable reaction rate [RR= 0.44, 95% CI (0.28, 0.68), P= 0.000 2], as well as the distinction was statistically substantial. VERDICT: The efficiency of Xiaoer Chiqiao Qingre Granules combined with Azithromycin Bnf in the therapy of kids with Mycoplasma pneumoniae pneumonia is far better than that of azithromycin alone, as well as it is much safer.
Deng Zhuoyan of Shaanxi Woodland Design Medical facility as well as others discussed the efficiency as well as safety of montelukast sodium combined with Azithromycin Bnf in the treatment of children with cough variant asthma (CVA). Approaches: From March 2018 to March 2020, 90 kids with CVA in our hospital were split into the control group (50 situations) and also the research study group (40 situations) according to the random number table approach. The control group was offered Azithromycin Bnf treatment, and the study group was provided montelukast salt combined with azithromycin treatment. The lung function indexes, inflammatory aspect indexes and the incidence of difficulties were compared in between the two groups. Results After treatment, the maximum expiratory flow price at 25% of the essential capability (MEF25), the optimum expiratory flow price at 50% of the important capacity (MEF50), the optimum mid-segment expiratory circulation rate (MMEF25-75), and the forced expiratory quantity in 1 second (FEV1) were observed in both groups. )/ forced important capacity (FVC) were raised, and also the study group was greater than the control group, the difference was statistically significant (P<0.05). After therapy, the degrees of growth necrosis factor-α (TNF-α), C-reactive protein (CRP), leukocyte matter (WBC) and also neutrophil percent (NEUT%) in both groups were reduced, and the study group was lower than the control group, The difference was statistically significant (P<0.05). The complete occurrence of damaging responses in the study group throughout therapy was less than that in the control group, and also the distinction was statistically considerable (P<0.05). Final thought: Montelukast sodium incorporated with Azithromycin Bnf in the treatment of children with CVA can effectively improve their pulmonary function, lower respiratory tract swelling, as well as has high safety and security.
Based upon the study on the etiological circulation characteristics of early rupture of membranes and also the scenario of microbial resistance, Liu Honggeng et al. (PPROM) Efficiency and also Safety And Security of Maternal and Infant Outcomes in Expecting Ladies. Approaches: A total of 143 pregnant women with PPROM that delivered in Sino-Singapore Eco-city Hospital of Tianjin Medical University and Binhai Health Center of Tianjin Medical College General Medical Facility from 2018 to 2019 were selected as well as randomly split right into an observation team of 72 and also a control group of 71, specifically offered (cefotaxime or Ceftazidime incorporated with Azithromycin Bnf) as well as (ampicillin combined with erythromycin) two regimens of treatment, the incubation duration of pregnant and lying-in females, neonatal birth condition as well as maternal-infant infection were contrasted between the two groups. Outcomes The incubation duration of the observation team was significantly longer than that of the control group. The occurrence of irregular body temperature and PCT prior to shipment, clinical chorioamnionitis, histological chorioamnionitis as well as pregnancy termination by cesarean section were lower in the monitoring group than in the control group. In the control group, the distinction was statistically significant (P<0.05). The weight of the neonates in the observation group was higher than that of the neonates in the control group, and the incidence of neonatal pneumonia in the observation group was lower than that in the control group, with analytical importance (P<0.05). Final thought: Escherichia coli as well as irregular virus arsociated with preterm premature tear of membrane layers in Tianjin area, and also the bacterial drug resistance circumstance is more serious than that in international countries. The system proposed in this study can effectively improve the maternal as well as infant results of females with preterm premature rupture of membranes, and also provide a basis for the risk-free, effective and sensible use of antibiotics in special populations.
Hu Lian, Division of Internal Medicine, Jiangxi Honorary Armed Force Recovery Healthcare facility, discussed the application value of Azithromycin Bnf combined with cefuroxime in people with hospital-acquired pneumonia. Techniques: A total amount of 60 clients with hospital-acquired pneumonia who were confessed to our health center from December 2018 to December 2019 were chosen as the research study objects, and also separated right into the control group as well as the observation group by arbitrary number table method, 30 situations in each group. The control group was offered Azithromycin Bnf treatment, as well as the monitoring team was provided azithromycin combined with cefuroxime therapy. The clinical efficacy, signs and symptom loss time, safety, and microbial clearance price were contrasted between the two teams. Results: The total reliable price of the observation team was more than that of the control team (P<0.05). The disappearance time of relevant signs and symptoms (fever, expectoration, shortness of breath, lung rales) in the observation team was much shorter than that in the control group (P<0.05). There was no substantial difference in the incidence of adverse responses between the two teams. The bacterial clearance price in the observation team was greater than that in the control group (P<0.05). Before treatment, there was no substantial distinction in the degrees of TNF-α, VEGF, MMP-9 and WBC between both groups; after treatment, the degrees of TNF-α, VEGF, MMP-9 and also WBC in the monitoring team were less than those in the control team (P<0.05). ). Verdict: Azithromycin Bnf incorporated with cefuroxime has a significant effect in the treatment of hospital-acquired pneumonia, and can properly remove bacterial strains, with guaranteed curative result and also high safety and security.