Astragalus Extract Powder

Molecular Formula: NULL

Formula Weight: 0

ZSpharmac: Astragalus Extract Powder Supplier

Product Name: Astragalus Extract Powder

CAS No: 111-42-2

Purity: 99%

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Basic Info

Product Name:	Astragalus Extract Powder
Other Names:	Astragalus Extracts
CAS:	111-42-2
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	Brown Powder
EINECS No.:	NULL
Storage:	2-8°C
Provide:	Astragalus Extract Powder MSDS； Astragalus Extract Powder COA

What is Astragalus Extract Powder ?

Astragalus was first recorded in “Shen Nong’s Materia Medica”. Westerners began to recognize the medical value of Astragalus in the 19th century. It was first described by Dr. Alexander Von Bange, a Russian doctor who studied East Asian plants in 1868. In 1911, “Chinese Raw Materials”, G.A. Astragalus “has an excellent reputation as a tonic, cough suppressant, and diuretic,” Stuart says. Astragalus Extract Powder is a product extracted from the dried root of Astragalus Astralgusmembranceus (Fisch) BgeVar.mongholicus (Bye) Hsiao. Commercial extracts are usually standardized to contain 70% astragalus polysaccharides.

Herbal Ingredients of Astragalus Extract Powder

1. Flavonoids: Mongolian Astragalus origin contains quercetin, kaempferol, isorhamnetin, rhamnocitrin, formononentin, calycosin, and calycosin-7-O-β -D-Glucoside, Actascoisoflavone-7-O-β-D-Glucoside-6 ″-O-malonyl ester, 9,10-dimethoxypteroline-3-O-β-O-glucose Glycoside, (6aR, 11aR)-3-hydroxy-9, 10-dimethoxy pterostilbene, (6aR, 11aR)-3-hydroxy-9, 10-dimethoxy pterostilbene-3-O-β- D-glucoside, (3R)-7,2-dihydroxy-3 ′,4 ′-dimethoxyisoflavan-7-O-β-D-glucoside, 2 ′-hydroxy-3 ′,4 ‘-Dimethoxyisoflavane-7-O-β-D-glucoside, (3R)-7,2′-dihydroxy-3′,4′-dimethoxyisoflavane, (3R) -2 ′,3 ′-dihydroxy-7,4 ′ dimethoxyisoflavone, (6aR,11 aR)-10-hydroxy-3,9-dimethoxypurane, formononetin-7-O – beta-D-glucoside-6″-O-malonyl ester, pterostalin glucoside-6′-O-malonyl ester, isoflavane glucoside-6’-O-malonyl ester.
2. Saponins: Astragalus saponins, (Astramembrannin,), astragaloside ～ (Astragaloside ～), soybean saponin (Soyasaponin) in Astragalus membranaceus, amongst them, Astragaloside along with Astragaloside For the very same substance, that is, astrasieversianin (Astrasieversianin). Mongolian Astragalus has astragaloside,,, as well as carrotin.
3. Polysaccharides: Astragalan-( Astragalan-, APS1, 2, 3), dextran AG-1, AG-2, heteropolysaccharides AH-1, AH-2, etc are consisted of in Astragalus mongolica.
4. Amino acids: mainly proline, along with γ-aminobutyric acid, asparagine, arginine, aspartic acid, cystine, glycine, serine, etc 5. Organic acids: typically ferulic acid, isoferulic acid, p-hydroxybenzoic acid, caffeic acid, chlorogenic acid, palmitic acid, linolenic acid as well as also linoleic acid. Others include trace element, riboflavin, folic acid, vitamin P, sitosterol, lupeol, n-hexadecanol, and so forth.

Applications of Astragalus Extract Powder

Astragalus Remove Powder, the dried out beginning remove of the leguminous plant Astragalusmembranaceus (Fisch.) Bge., has the features of enhancing resistance, enhancing power, anti-fatigue, anti-mutation, protecting liver along with inhibiting osteoclasts. Astragalus polysaccharide has the result of decreasing blood fat, that is, lowering cholesterol in addition to triglyceride, along with boosting high-density lipoprotein; it can quit as well as deal with cardio and additionally cerebrovascular conditions, such as atherosclerosis, coronary artery disease, external vascular condition, as well as hyperlipidemia Wait.Astragaloside IV has the impact of dramatically lowering blood sugar level, glycosylated hemoglobin and pee healthy protein, and also can decrease AGEs in product, revealing that astragaloside IV has antioxidant effect, and has repressive result on aldose reductase, along with inhibition of mesangial cell spreading. result. Astragalus enhances our vigor as well as can transform dull, droopy skin right into company, radiant skin. It restores the skin’s all-natural balance by eliminating toxins, boosting collagen production, minimizing inflammation, enhancing blood circulation and restoring skin cells. Astragalus Essence Powder can enhance the immune function of the body, considerably advertise the manufacturing of antibodies in the body, take part in the immune guideline of the body, and can advertise the production of immune variables.

The combination of polysaccharides in Astragalus Essence Powder and also total ginsenosides can considerably raise the variety of peripheral blood leukocytes and also immune body organ indexes in computer mice. Modern pharmacological research studies have actually revealed that astragalus can improve myocardial contractility, and also the calycosin had in astragalus has a safety result on vascular endothelial cells. Astragalus additionally has a certain safety effect on organs such as liver, kidney, tummy and lungs. It can prevent the decrease of liver glycogen. Astragalus has the micronutrient selenium, which can additionally indirectly trigger the liver detoxification enzyme system, thereby safeguarding the liver. Astragalus has a substantial repressive result on deadly growths such as liver cancer cells, colon cancer cells, lung cancer cells, and breast cancer cells. It can hinder the spreading of breast cancer cells and colon cancer cells, as well as advertise the set death of lump cells. Astragalus additionally has a specific healthcare result, can get rid of complimentary radicals in the body, as well as hold-up aging. Astragaloside IV can shield mitochondria and lower the cytoplasmic release of Cytc, blocking the mitochondrial apoptotic pathway. Furthermore, Astragalus also has particular functions of protecting nerves, reducing high blood pressure, anti-fatigue, anti-bacterial, and antiviral. Astragalus remove is rich in flavonoids. Experimental studies have actually revealed that: Astragalus Extract Powder can dramatically lower the degree of ear swelling in mice, and minimize the number of wriggling reactions in mice boosted by glacial acetic acid. The outcomes show that Astragalus Essence Powder has obvious anti-inflammatory and also analgesic impacts, and the result is greater in big dosages apparent.

Preparation of Astragalus Remove Powder

A preparation method of Astragalus Remove Powder comprises the steps:

Step 1. Take the Radix Astragali medicinal material, 20-25 times the volume of 80% ethanol, adjust the pH value to 4-5, extract the temperature at 40-44°C, extract for 5-8 hours, filter to obtain the filter residue, and then use the filtrate to Pass through the D-101 macroporous resin at a speed of 0.8-1.2ml/min, set aside, recover ethanol and concentrate; for the ethanol elution part, the eluent is decompressed and the solvent is recovered;

Step 2, take the filter residue of step 1, add 20-25 times the volume of 80% ethanol, adjust the pH value to 4-5, extract the temperature at 40-44°C, extract for 5-8 hours, filter to obtain the filter residue, The filtrate passes through the D-101 macroporous resin at a speed of 0.8-1.2ml/min, and is set aside, and the ethanol is recovered and concentrated; for the ethanol eluted part, the eluent is reduced in pressure to recover the solvent;

Step 3, take the filtrate of step 1 and mix the filtrate of step 2, adjust the pH value to 7, concentrate under reduced pressure, the pressure is -0.09MPa~-0.12MPa, and concentrate to a relative density of 1.6~1.8 (25~30°C) extract, to obtain the Radix Astragalus extract, and the Astragalus Remove Powder contains calycosin, formononetin and total astragalus saponins, and the mass percentages are respectively 8%~0.85%, 0.6%~0.7%, 40%~45% .

TLC Identification Method of Astragalus Remove Powder

Method 1: Take an extract sample equivalent to 5g of medicinal materials, ultrasonically extract with 100ml of ethanol-water (57:43) mixture for 10min, filter, concentrate the filtrate under vacuum at 45°C, and use 10ml of ethyl acetate and water for the concentrate The mixture (1:1) was degreased, the upper layer was discarded, the lower layer was extracted twice with ethyl acetate, 5ml each time, the ethyl acetate layer was discarded, the aqueous layer was extracted with n-butanol three times, 5ml each time, combined The n-butanol extract was washed with water 3 times, 2ml each time, and the n-butanol was evaporated under vacuum, and the residue was dissolved in 1ml methanol, which was the test solution. Dissolve 1mg of astragaloside IV in 1ml of methanol, which is the reference solution. Using an automatic thin-layer spotter, suck 5 μl of the test solution and control solution and spot it on a 10×10cm silica gel 60F254HPTLC plate to form spots of 8mm in size, the distance between two spots is 6mm, and the distance between the baseline and the bottom of the plate is 8mm. Place in a 10×10cm developing tank (first saturate with 5ml developing agent for 10min), use chloroform-methanol-water (18:8:1) as developing agent, develop to 55mm from the edge of the lower plate, place in cold air for 5min to make the plate naturally dry. View at 254nm and 366nm; immerse the plate in sulfuric acid reagent (add 5ml of sulfuric acid to 95ml of frozen methanol) for 1 second, dry in cold air, heat at 110°C for 2min, and detect the derivatized plate under ultraviolet 366nm.

Method 2: Take 3g of Radix Astragali powder or an equivalent amount of extract, add 20ml of methanol, heat and reflux for 1 hour, filter, and add the filtrate to a neutral alumina column (100-200 mesh, 5g, inner diameter 10-15mm), Elute with 100ml of 40% methanol, collect the eluate, evaporate to dryness, add 30ml of water to the residue to dissolve, extract twice with n-butanol saturated with water, 20ml each time, combine the n-butanol solution; wash with water twice, 20ml each time Discard the water, evaporate the n-butanol solution to dryness, add 0.5ml of methanol to dissolve the residue, and use it as the test solution. Take another astragaloside IV reference substance, add methanol to make a solution containing 1mg per 1ml, as the reference substance solution. Take 2 μl of each of the above two solutions, spot on the same silica gel G thin-layer plate, use the lower layer solution of chloroform-methanol-water (13:7:2) as the developer, develop, take out, dry in the air, and spray with 10 % sulfuric acid ethanol solution, heated at 105°C until the color of the spots is clear. In the chromatogram of the test product, on the position corresponding to the chromatogram of the reference product, the same brown spots are shown under sunlight; the same orange-yellow fluorescent spots are shown under the ultraviolet lamp (365nm).

About That Product:
If you need Astragalus Remove Powder, this cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Astragalus Remove Powder manufacturer and supplier, ZSpharmac will provide Astragalus Remove Powder raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.