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Astragaloside IV CAS 84687-43-4

Molecular Formula: C41H68O14

Formula Weight: 784.97

ZSpharmac: Astragaloside IV Raw Material Supplier

Product Name: Astragaloside IV
CAS No: 84687-43-4
Purity: 99%

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Basic Info

Product Name:Astragaloside IV
Other Names:Astragalus Extract
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Neat
EINECS No.:1532714-185-1
Provide:Astragaloside IV MSDS;
Astragaloside IV COA

What is Astragaloside IV?

Astragalus get rid of is a product extracted from the dried origins of Astralgusmembranceus(Fisch)BgeVar.mongholicus(Bye)Hsiao. [Unrefined medication sources] There have to do with 1,600 varieties of Astragalus plants on earth, and there are greater than 200 types in my country. Presently, concerning 7 ranges are utilized for medical objectives. Astragalus membranaceus is primarily dispersed in Heilongjiang, Liaoning, Inner Mongolia, Hebei, Shandong, Shanxi, Shaanxi, Ningxia, Gansu, Qinghai, Xinjiang, Sichuan and Yunnan areas, and is furthermore found in Mongolia, North Korea and Russia. Industrial Astragalus Buguiqi is generally dispersed in the Greater Khingan Hills, Nenjiang, Aihun, Sunwu and different other locations, and Molidawa Banner in Inner Mongolia. Ninguguqi is mainly spread in Ning’an, Dongning, Linkou, Muling, and Hailin in Heilongjiang Area. Zhenguguqi is primarily dispersed in Hebei and Zhangjiakou locations. Mongolian Astragalus is primarily spread in Jilin, Hebei, Shanxi, Inner Mongolia and numerous other areas in my country, and is furthermore dispersed in Mongolia and Russia. Wild Astragalus resources are restricted in my nation, and both Astragalus membranaceus and Astragalus mongolica are noted as nationwide third-level crucial secured kinds. Presently, clinical products are primarily grown varieties, mainly developed in Hunyuan, Fanzhi, Yingxian, Daixian, Guangling in Shanxi, Guyang, Wuchuan, Zhuozi in Inner Mongolia, Heilongjiang and Jilin.

Astragaloside IV Property

Melting point 295-296°C
Boiling point 895.7±65.0 °C(Predicted)
density 1.39
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Methanol (Slightly, Sonicated), Pyridine (Slightly)
form neat
color White to Off-White


Pharmacological Effects of Astragaloside IV

Astragaloside IV Assay Method

Resolution of the material of astragaloside IV by HPLC technique
Chromatographic conditions: column: C185u4.6 mm × 250mm; mobile phase: acetonitrile-water (1:2); flow rate: 0.8 ml/min; column temperature: 25 ° C; detection wavelength: 200nm.
Prep work of examination solution: Specifically weigh 0.1 g of the essence powder, add an appropriate amount of water to dissolve it with ultrasound, after that drink and remove with 15ml × 4 n-butanol (water saturated), separate the n-butanol layer, evaporate to dryness, and use methanol to eliminate the residue Dissolve and readjust the volume to 10ml, mix well and travel through a 0.45 μm microporous filter membrane layer.
Prep work of typical solution: Specifically weigh a proper amount of astragaloside IV requirement, dissolve it in methanol, and prepare a remedy with a focus of 0.1 mg/ml.
Determination technique: Utilize a micro-injector to absorb 20 μl of the examination solution and control solution respectively, inject them into the fluid chromatograph, document the peak location, and determine the material according to the peak area exterior requirement approach.

Astragaloside IV Extraction Process

The content of astragaloside IV in Astragalus membranaceus is really reduced. Presently, conventional procedures such as decoction water removal and product reflux ethanol removal are made use of to extract astragaloside IV, which have the downsides of high removal temperature, reduced extraction price, and lengthy removal. The most up to date extraction technologies consist of high-speed centrifugation, microwave-assisted extraction, ultrasonic removal, ultrafiltration, supercritical fluid removal, ultra-high stress extraction, and high-speed countercurrent removal. New extraction technology plays a crucial function in boosting the extraction price of astragaloside IV, reducing the extraction time, and avoiding the damage of energetic components.
The procedure of drawing out astragaloside IV by carbon dioxide supercritical removal technique: evaluate 15g of astragalus, crush it to 40 mesh, placed it right into the extraction kettle, and inject a particular amount of entrainer (volume fraction 75% ethanol) into it. Location the extraction pot right into supercritical equipment. Readjust the temperature level and pressure of the supercritical carbon dioxide fluid, pump the supercritical liquid right into the extraction kettle at a particular circulation rate, collect the remove via cyclone separation, and centrifuge to focus and evaporate the extract to dry skin.
The optimized process conditions for carbon dioxide supercritical removal of astragaloside IV are: removal pressure 40Mpa, temperature 45 ° C, extraction time 2 hours, entrainer 95% ethanol, entrainer dose 4ml (95% ethanol)/ g (completely dry astragalus powder), CO2 circulation price is 10kg/kg.

About Products:
If you need the cosmetic raw material Astragaloside IV, please contact our service staff directly and we will provide you with high-quality products at the best price.
As an experienced Astragaloside IV manufacturer and supplier, ZSpharmac will provide Astragaloside IV raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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