Astaxin CAS 472-61-7

Molecular Formula: C40H52O4

Formula Weight: 596.85

ZSpharmac: Astaxin Supplier

Product Name: Astaxin

CAS No: 472-61-7

Purity: 99%

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Basic Info

Product Name:	Astaxin
Other Names:	Astaxanthin
CAS:	472-61-7
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	Pink to Very Dark Purple Powder
EINECS No.:	207-451-4
Storage:	-20°C
Provide:	Astaxin MSDS； Astaxin COA

What is Astaxin?

Astaxin is a ketone or carotenoid, pink in color, fat-soluble, insoluble in water, soluble in all-natural solvents. It frequently exists in the organic globe, specifically in the plumes of water animals such as shrimp, crab, fish as well as additionally birds, and likewise contributes in color development. Astaxin is a non-vitamin A carotenoid that can not be changed to vitamin A in animals. Astaxanthin is a fat-soluble in addition to water-soluble pigment that exists in aquatic microorganisms such as shrimp, crab, salmon, in addition to algae. The body can not generate astaxanthin by itself.

Astaxin Property

Melting point	215-216 °C
Boiling point	568.55°C (rough estimate)
density	0.9980 (rough estimate)
refractive index	1.4760 (estimate)
storage temp.	-20°C
solubility	DMSO: soluble1mg/mL (warmed)
form	powder
pka	12.33±0.70(Predicted)
color	pink to very dark purple

Astaxin Uses

1. Antioxidant attribute
Astaxin has the attributes of safeguarding skin in addition to eyes, securing versus cardio aging, withstanding radiation, quiting in addition to handling Alzheimer’s problem and additionally cancer. The aging of the body is mostly induced by oxidation activated by complimentary radicals. Astaxanthin gets in human cells, right does away with oxygen totally free radicals in cells, improves cell regrowth capability, along with safeguards regular human body features.

Scientists have really been creating brand-new antioxidant products: the first-generation antioxidant products are vitamins; the second-generation antioxidant materials are β-carotene, SOD, coenzyme Q10, and more; the third-generation antioxidant items are anthocyanins, blueberry remove, grape seed significance, environment-friendly tea, lycopene, lipoic acid, and so on; the fourth-generation antioxidant compound is natural astaxanthin.Research studies have actually revealed that the antioxidant task of Astaxin in Haematococcus pluvialis is a lot higher than that of β-carotene, grape seed significance, lipoic acid, lutein, and also vitamin E.

2. Anti-cancer function
Astaxin can significantly prevent the preliminary carcinogenesis created by chemical compounds, as well as has the effect of preventing expansion and advertising immune feature of epithelial cells subjected to carcinogens, such as preventing the development of oral cancer, bladder cancer cells, colon cancer, bust cancer cells in addition to gastric cancer cells. Astaxin can additionally deteriorate the carcinogenicity of aflatoxin, in addition to has a terrific repressive outcome on aflatoxin-induced liver development cells.

3. Anti-ultraviolet radiation
Ultraviolet radiation is a vital resource of skin photoaging and skin cancer cells. The strong antioxidant properties of Astaxin can make it a trusted photoprotectant, eliminate entirely cost-free radicals that create skin aging, guard cell membrane layer layers as well as also mitochondrial membranes from oxidative damages, as well as likewise quit skin damage. photoaging.

4. Secure Against Cardiovascular Diseases
Research study researches have actually revealed that Astaxin can substantially improve HDL and reduce LDL in the body, in which HDL can be boosted from the original 49.7 mg/dL ± 3.6 mg/dL to 66.5 mg/dL +5.1 mg/dL, so it is speculated that Astaxin can lower the tons. The oxidation of lipoprotein can be taken advantage of to stay clear of coronary heart disease, arteriosclerosis and likewise ischemic mind injury.

5. Improve immunity
Astaxin can considerably affect the immune feature of animals. In the existence of antigens, it can drastically boost the capability of splenocytes to create antibodies, boost the function of T cells, as well as stimulate the production of immunoglobulins in the body. Astaxanthin has a solid activity of generating cell division as well as has crucial immune regulation feature.

6. Eliminate tiredness as well as additionally improve body metabolic process
Astaxin can be taken advantage of as an antioxidant to prevent the oxidative damages of free of charge radicals on the body. Oral astaxanthin can furthermore reinforce cardiovascular metabolic process, enhance muscular tissue stamina and muscle mass resistance, quickly calm workout fatigue, as well as additionally lower delayed muscular tissue discomfort after laborious exercise.

Astaxin Synthesis Method

A method for isolating and purifying Astaxin from Phaffia yeast, comprising the following steps:
Step 1. Phaffia yeast cell wall breaking: Use dimethyl sulfoxide to break the Phaffia yeast cell wall. The breaking condition is: the cell and dimethyl sulfoxide are in mass-to-volume ratio, that is, g/ml, the ratio 1/2, at 55°C, break the wall for 5 minutes;
Step 2, crude extraction of Astaxin with acetone: after breaking the wall, extract with acetone at a material-to-liquid ratio of 1:15. The material-to-liquid ratio is the mass-to-volume ratio of Phaffia thallus to acetone, i.e. g/ml, extract 2 times, and combine The extract solution is removed by low-temperature rotary evaporation to remove acetone, and the remaining component is the crude extract of astaxanthin dissolved in dimethyl sulfoxide, and the residual component is the primary crude extract of astaxanthin;
Step 3, degreasing and removing low-polarity carotenoids: Extract the primary astaxanthin crude extract with petroleum ether, the extraction ratio is Astaxin primary crude extract: petroleum ether volume ratio 1:2, the extraction times is 2 times, discard The upper layer of petroleum ether is used to collect the lower layer solution, which is the secondary crude extract of astaxanthin;
Step 4. Removal of dimethyl sulfoxide: Mix the secondary crude extract of Astaxin with saturated aqueous sodium chloride solution precooled to 4°C in a volume ratio of 1:3.5, and extract the mixed solution with ethyl acetate. The amount of ethyl acetate It is 3 times the volume of the second crude extract of astaxanthin; collect the ethyl acetate phase, and evaporate to dryness at low temperature to obtain astaxanthin powder with higher purity;
Step 5, crystallization: add dichloromethane to dissolve the Astaxin powder obtained in step 4 until the astaxanthin powder is completely dissolved, then add methanol to the solution until crystals are precipitated, let stand, and dichloromethane volatilizes naturally. Astaxanthin crystals were precipitated; centrifuged at 4°C and 9961×g for 10 minutes, and the crystals at the bottom were collected as Astaxin.

How to Distinguish Between Good and Bad Astaxin

Astaxanthin from different resources has various stereoisomers and chemical structures. Haematococcus pluvialis is the most natural resource of astaxanthin, with high safety and security as well as absorption rate; astaxanthin from yeast and also other fungi, chemical synthesis, and shrimp as well as crab covering waste has reduced pureness as well as security, which is not for human body take in.

1 identify devices
Cut the rubber of the pill with scissors, and the great astaxanthin oil will spread out rapidly when dropped right into a mug of water, which is conducive fully and quick absorption of the gastrointestinal system. Nonetheless, when the inferior astaxanthin oil is gone down right into clear water, it comes to be a swelling of black paste, which can not be spread and also is not for absorption. Inferior products often have nontransparent capsule skins due to the fact that food additive is utilized to cover blemishes in the rubber skin as well as components.

2 acknowledgment elements
If the content of astaxanthin in one astaxanthin soft capsule is 4-5 mg, after that the color of one capsule mixed with one kilogram of normal cooking oil is close to the shade of the high-grade salmon, due to the fact that the astaxanthin of the top-grade salmon is The aspect web content is 5 milligrams per kilogram.

About Products:
If you need Astaxin as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Astaxin manufacturer and supplier, ZSpharmac will provide Astaxin raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.