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Arctium Lappa Root Extract

Molecular Formula: N/A

Formula Weight: 0

ZSpharmac: Arctium Lappa Root Extract

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Product Name: Arctium Lappa Root Extract
CAS No: 0
Purity: 99%

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Basic Info

Product Name:Arctium Lappa Root Extract
Other Names:Burdok Root P.E
CAS:0
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Viscous Liquid
EINECS No.:NULL
Storage:2-8°C
Provide:Arctium Lappa Root Extract MSDS;
Arctium Lappa Root Extract COA

What is Arctium Lappa Root Extract?

Arctium Lappa Root Extract is the dry origin remove of Arctium Lappa L. of Compositae, consisting of substances such as burdock acid, aldehydes, polyynes and polysaccharides. It has medicinal activities such as anti-bacterial, antiviral, antioxidative, antifatigue, regulating lipid metabolic rate and also sugar metabolism problem, antitumor, antimutation, immune policy, anti-inflammatory, laxative and so forth.

Arctium Lappa Root Extract Extraction Source

[Base source] is the dry root of Arctium lappa L. of the Compositae.
[Origin] Mainly produced in Jilin Huadian, Jiaohe, Dunhua, Yanji, Liaoning Benxi, Qingyuan, Fengcheng, Huanren, Heilongjiang Wuchang, Shangzhi, Fujin, Acheng, Zhejiang Tongxiang, Jiaxing, with the largest output in the northeast.
[Plant form] Burdock is a large biennial herb, 1-2m high, with many branches on the upper part, purple-brown, and longitudinal ribs. Roots stout, fleshy, conical. Basal leaves are large, clustered, and have long stalks. Stem leaves alternate, petiolate, leaf blade broadly ovate or heart-shaped, margin wavy or dentate, base heart-shaped, densely white pubescent below. The leaves on the upper part of the stem gradually become smaller. Capitulum clustered on top of stem or arranged into corymbs, with shallow grooves on the surface, densely hairy; involucre spherical, numerous bracts, imbricate, lanceolate or linear-lanceolate, apex extended to acuminate , the end is hooked. Flowers are small, reddish or reddish-purple. Achenes oblong, with longitudinal ribs, gray-brown, short thorn-like crown, yellowish brown. The fruit is oblong-ovate, slightly curved, truncated at both ends, slightly flattened, 5-7mm long, 2-3mm in diameter, grayish-brown or grayish-brown on the surface, with many small purple-black spots, and obvious longitudinal ridges 5 ~8. The apex is broad, with a ring, and the center has a point-like raised style residue; the base has a circular dimple-like stalk scar. The peel is hard, the seed coat is yellowish-white, and the cotyledons are 2, rich in oil.

 

Main Active Ingredients of Arctium Lappa Root Extract

At present, the active ingredients isolated from Arctium Lappa Root Extract are mainly amino acids (threonine, valine, methionine, isoleucine, phenylalanine, lysine, aspartic acid and arginine, etc.) , trace elements (Ca, Mg, Fe, Mn, Zn, etc.), carbohydrates (burdock inulin, burdock oligosaccharide, burdock oligosaccharide, burdock polysaccharide, etc.), polyphenols (caffeic acid, chlorogenic acid, etc.), Alkynes (arctyl alcohol, arct ketone, arctic acid, etc.), volatile oils (dandelion sterol, sitosterol, β-elemene, etc.), flavonoids (arctidine, arctigen, etc.), glycosides, alkaloids, burdock succinic acid, oleanolic acid, ursolic acid, carotene, etc.

Arctium Lappa Root Extract Pharmacological Actions

Burdock root bark ethanol extract, water extract and burdock root meat ethanol extract, water extract have antibacterial effects on Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Aspergillus niger and yeast; 80% of burdock root Ethanol extract has a good inhibitory effect on Vibrio parahaemolyticus. The burdock inulin extracted from burdock root can inhibit Escherichia coli and promote the growth of lactic acid bacteria; the polyphenols chlorogenic acid can inhibit Escherichia coli, Shigella, Staphylococcus aureus, Bacillus subtilis, Garcinia cambogia For the growth of cocci and Legionella, the minimum inhibitory concentration (MIC) is 20-80 μg/ml; chlorogenic acid can increase the permeability of bacterial cell membranes, resulting in the disappearance of barrier function, and even a slight overflow of nucleotides, depleting cells Internal potential, the release of macromolecules in the cytoplasm, leading to apoptosis, thus playing an antibacterial effect. In terms of antiviral activity, arctigenin can directly inhibit or inactivate influenza virus, and has a strong anti-type 1 influenza virus effect in vitro. In vitro, chlorogenic acid can significantly inhibit the activity of adenovirus types 7 and 11, coxsackie B group type 3, and syncytial virus, but its antiviral mechanism is still unclear.

The ethanol extract and water extract of burdock root bark and the ethanol extract and water extract of burdock root meat all have certain antioxidant activities. Among them, Arctium Lappa Root Extract can significantly inhibit the auto-oxidative inhibition rate of pyrogallol and protect the aging of human erythrocyte membrane. The water extract of burdock root has strong scavenging ability to O2-, HO· and ROO·, the order is: ROO·>HO·>O2-, and the ability of the water extract of burdock root to remove O2- and HO· increases with the It is enhanced with the increase of mass concentration; Arctium Lappa Root Extract is stronger than Arctium Lappa Root Extract in scavenging free radicals. Water-soluble dietary fiber, chlorogenic acid and lignin in burdock root also have strong antioxidant activity. In terms of anti-aging effect, the results of a Drosophila survival experiment on burdock root extract using Drosophila as an animal model showed that burdock root has the effect of delaying aging, the most obvious with a mass fraction of 1%. Burdock root extract can significantly increase the reserve of hepatic glycogen in mice, prolong the time of mice swimming under load, and improve the blood lactate clearance ability. Burdock oligofructose can significantly improve exercise endurance and hypoxia tolerance time in mice, reduce the content of blood lactic acid (LAC) and blood urea nitrogen (BUN) after exercise, increase the content of muscle and liver glycogen, and has a good anti-fatigue effect . Arctium aglycone enhances mitochondrial regeneration and fatty acid oxidation, thereby enhancing endurance in mice.

Studies have shown that Arctium Lappa Root Extract can protect carbon tetrachloride or acetaminophen-induced liver damage in mice and liver damage caused by alcoholism, and reduce alanine aminotransferase (ALT) in liver tissue in a dose-dependent manner The level of aspartate aminotransferase (AST) and aspartate aminotransferase (AST) can also be seen pathologically to reduce the degree of liver damage. The chloroform extract of burdock root can protect animals from gastric mucosal damage by reducing gastric acid secretion, and the active ingredient chlorogenic acid (50mg/kg) can protect mice from lipopolysaccharide (LPS)-induced acute lung injury (ALI).

Arctium Lappa Root Extract can significantly reduce serum total cholesterol (CHOL), TG and low-density lipoprotein (LDL) levels in hyperlipidemia rats, increase high-density lipoprotein (HDL) levels, alleviate liver fat lesions, and reduce mice The body mass and the fat mass around the genitals have good hypolipidemic and weight loss effects.

Subcutaneous injection of crude burdock root extract can significantly reduce carrageenan-induced airway edema in rats, and can also significantly inhibit carrageenan-induced foot swelling.

The extracts of various parts of burdock root (petroleum ether, chloroform) have different degrees of cytotoxicity on mouse hepatoma cells (HepA) and mouse sarcoma cell line (S180), and there is a certain dose-effect relationship. Its n-butanol extract and water extract can reduce the mutagenesis effect of doxorubicin on TA98 strain and protect the injury of mouse bone marrow cells caused by doxorubicin. In vitro experiments showed that the inhibitory rates of Arctium Lappa Root Extract on Chinese hamster ovary (CHO) tumor cells were (21.29±1.25)% and (38.68±1.83)% at the mass concentration of 5 and 10 mg/ml, respectively, and the mass concentration was 20 mg. The inhibition rate was up to (70.11±2.41)% at /ml. Burdock oligosaccharide can promote the activity of macrophage acid phosphatase, enhance the macrophage phagocytosis function and the ability to produce nitric oxide (NO) in tumor-bearing mice.

Arctium Lappa Root Extract aspartic acid and arginine have the effect of invigorating the brain; burdock inulin has the effect of treating coronary heart disease and diabetes; chlorogenic acid can also resist HIV and allergies.

About Products:
If you need Arctium Lappa Root Extract, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
Our company, as an experienced Arctium Lappa Root Extract manufacturer and supplier, ZSpharmac will provide Arctium Lappa Root Extract raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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