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Ammonium Thioglycolate Solution CAS 5421-46-5

Molecular Formula: C2H7NO2S

Formula Weight: 109.15

ZSpharmac: Ammonium Thioglycolate Solution Supplier

Product Name: Ammonium Thioglycolate Solution
CAS No: 5421-46-5
Purity: 99%

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Basic Info

Product Name:Ammonium Thioglycolate Solution
Other Names:Ammonium Thioglycolate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless Solution
EINECS No.:226-540-9
Provide:Ammonium Thioglycolate Solution MSDS;
Ammonium Thioglycolate Solution COA

What is Ammonium Thioglycolate Solution?

Ammonium thioglycolate is a chemical utilized to align hair. The chemical is much less harmful to the scalp and hair than various other items, and it doesn’t scent too strong. It functions by making hair follicles a lot more permeable as well as breaking down the disulfide bonds that make hair frizzy. This product is made use of as the first step in a thermionic straightening system.

Ammonium Thioglycolate Remedy is milder and as a result less destructive to hair than various other chemicals that can be utilized in straighteners. The chemical’s thiol group, -SH, enables it to act as a reducing agent. This chemical donates an electron to an additional substance (chemical bond) to be broken down or lowered. There are many disulfide bonds in hair strands. Extremely curly hair needs a lot of disulfide bonds, while straight hair requires much less. The ammonium in this compound causes the hair to swell, which after that permits the thioglycolate to get in the hair as well as minimize or break down the disulfide bonds in the hair.

Complete rinsing is needed to remove Ammonium Thioglycolate Remedy. After the hair is styled as well as corrected, the next action is to use a hydrogen peroxide option. The hydrogen peroxide remedy produces new bonds in the new hair. As a whole, the less bonds formed, the much less frizzy hairs will be. If this process is repeated way too much, the hair comes to be weak as well as susceptible to breakage.

There are several advantages to utilizing this chemical rather than Guanidine Hydroxide or Sodium Hydroxide. Ammonium thioglycolate has a low pH between 9-9.5, while salt hydroxide has a high pH of 14. The less alkaline chemicals will not harm the scalp or hair. Conditioning products are usually made use of before hydroxide products, yet not with Ammonium Thioglycolate Remedy. Also, this product does not have a solid scent when applied on the hair. Disulfide chemicals, on the other hand, have a bad smell, and other leisure chemicals can have a very solid, pungent smell. The sulfide created from thioglycolate converts the sulfur right into a non-volatile or non-odor form of the chemical.

Bioionic or thermionic systems also utilize this product to decrease internal stress and structure in hair strands. The hair is reorganized with warm (normally a perm) and after that styled right into a new straight look. Unlike various other aligning items, this system offers well for straightening hair that is remarkably glossy as well as soft.

Ammonium Thioglycolate Solution Property

Melting point 139-139.5 °C
Boiling point 115℃[at 101 325 Pa]
density 1.22
vapor pressure 0.001Pa at 25℃
form Solution
Specific Gravity1.245 (25℃)
color Clear colorless
Odorstrong skunk-like odor
Water Solubility Miscible


Ammonium Thioglycolate Solution Uses

  1. The major feature of Ammonium Thioglycolate Service in cosmetics and skin treatment items is as a perm agent. The risk variable is 4, which is reasonably secure and also can be made use of with self-confidence. Expectant females need to make use of cosmetics and also skin treatment products including ammonium thioglycolate with caution. Ammonium thioglycolate is not acne-causing.
  2. Ammonium Thioglycolate Option is utilized as a reagent for determining iron and in the pharmaceutical industry.
  3. Ammonium Thioglycolate Service can also be made use of as a PVC stabilizer, and so on.

Preparation of Ammonium Thioglycolate Solution

Ammonium Thioglycolate Solution can be prepared from sodium chloroacetate and thiourea:

ClCH2COONa + H2NC(S)NH2 —80℃→ HN=C(NH2)S-CH2COOH + NaCl

2 HN=C(NH2)S−CH2COOH + Ba(OH)2 → Ba(SCH2COO)2Ba + 2 NH2CONH2 + H2O

Ba(SCH2COO)2Ba + 2 NH4HCO3 → 2HSCH2COONH4 + 2 BaCO3

About Products:
If you need Ammonium Thioglycolate Solution, the cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Ammonium Thioglycolate Solution, ZSpharmac will provide Ammonium Thioglycolate Solution raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Ammonium Thioglycolate Solution Quotation