Zhishang Chemical

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Zhishang Chemical

Ammonium Thioglycolate CAS 5421-46-5

Molecular Formula: C2H7NO2S

Formula Weight: 109.15

ZSpharmac: Ammonium Thioglycolate Supplement

Product Name: Ammonium Thioglycolate
CAS No: 5421-46-5
Purity: 99%

Basic Info

Product Name:Ammonium Thioglycolate
Other Names:Ammonium Thioglycolate, 70% Solution in H2O
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Organic Chemical Raw Materials
Appearance:Clear Colorless Solution
EINECS No.:226-540-9
Storage:Warehouse Ventilation Low Temperature Drying
Provide:Ammonium Thioglycolate MSDS;
Ammonium Thioglycolate COA


What is Ammonium Thioglycolate?

Ammonium thioglycolate is a chemical used to straighten hair. Compared to other products, the chemical causes less damage to the scalp and hair, and the smell is not too strong. It works by making hair follicles more permeable and breaking down the disulfide bonds that make hair frizzy. This product is used as the first step in a thermionic straightening system.

Ammonium thioglycolate is milder and therefore less damaging to hair than other chemicals that can be used in straighteners. The chemical’s thiol group, -SH, makes it a reducing agent. This chemical gives an electron to another compound (chemical bond) to be broken down or reduced. There are many disulfide bonds in the hair strands. Very curly hair needs a lot of disulfide bonds, while straight hair needs a lot less. The ammonium in this compound causes the hair to swell, which then allows thioglycollate to enter the hair and reduce or break down the disulfide bonds in the hair.

Thorough rinsing is required to remove ammonium thioglycolate. After the hair is styled and straightened, the next step is to apply a hydrogen peroxide solution. Hydrogen peroxide solution can create new bonds in new hairstyles. In general, the fewer bonds are formed, the less frizzy strands will be. If this process is repeated too much, the hair becomes brittle and prone to breakage.

Replacing Guanidine Hydroxide or Sodium Hydroxide with this chemical has many benefits. Ammonium thioglycolate has a lower pH, between 9-9.5, while sodium hydroxide has a pH as high as 14. Chemicals that are less alkaline will not damage the scalp or hair. Conditioning products are usually used prior to the use of hydroxide products, but not with ammonium thioglycolate. In addition, the product does not have a strong smell when applied to the hair. On the other hand, disulfide chemicals smell bad, and other relaxation chemicals produce very strong, pungent odors. The sulfide produced from thioglycolate converts the sulfur into a nonvolatile or non-odorous form of the chemical.

Bio-ionic or thermionic systems also use this product to reduce internal stress and structure in hair strands. The hair is reconstructed with heat (normally a perm) and then styled into a new straight style. Unlike other straightening products, this system sells well because the straightened hair is very shiny and soft.

Ammonium Thioglycolate Properties:

Melting point 139-139.5 °C
density 1.22
form Solution
color Clear colorless
Specific Gravity1.245 (25℃)
Odorstrong skunk-like odor
Water Solubility Miscible


Ammonium Thioglycolate Uses

Ammonium thioglycolate contains sulfhydryl and carboxyl groups in its structure, which can be used as antioxidants, catalysts, etc., and is widely used in the field of chemistry. Ammonium thioglycolate is a daily chemical raw material developed in the 1940s. It is used as a depilatory agent and a hair curling agent in functional cosmetics. At present, thioglycolic acid and its salts (calcium salts, ammonium salts) are used in cosmetics. Calcium thioglycolate is mostly used. Its function in perming is mainly to break the disulfide bonds of amino acids in the hair, and then make the hair soft and produce a series of changes, and then use an oxidizing agent to restore the broken disulfide bonds and set the shape. Hair removal. The addition amount of ammonium thioglycolate in cosmetics should be appropriate. If the content exceeds 1.3, if the test method is too low, there will be no perm effect. If the content is too high, the curl retention rate will not be high.

Ammonium Thioglycollate Human Toxicity Extract and Non-Human Toxicity Extract

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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