American Ginseng Extract Powder CAS 50647-08-0

Molecular Formula: C42H66O17

Formula Weight: 842.96324

ZSpharmac: American Ginseng Extract Powder Supplement

Product Name: American Ginseng Extract Powder

CAS No: 50647-08-0

Purity: 99%

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Basic Info

Product Name:	American Ginseng Extract Powder
Other Names:	Panaxschinseng
CAS:	50647-08-0
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	Yellow Powder
EINECS No.:	0
Storage:	2-8℃
Provide:	American Ginseng Extract Powder MSDS； American Ginseng Extract Powder COA

What is American Ginseng Extract Powder?

American Ginseng Extract Powder is extracted from the origin of American ginseng Panaxquinquefolium L.a plant of the family members Araliaceae, with ginsenoside as the major energetic ingredient, and still has unstable oils, amino acids, inorganic aspects, sugars and also polysaccharides, fats and various other components. It has strong anti-leukemia cell (L1210) cytotoxic activity, and likewise has anti-cancer, antioxidant, anti-vomiting, cardiomyocyte protection and neuroprotective effects.

American Ginseng Extract Powder Chemical Composition

1. Saponins Saponins are mainly divided into 3 categories according to their parent structures: Dammarane, Oleanane, Ocotillol, 49 have been isolated so far. species, including the newly discovered ginsenosides Rb1, Rb2, Rb3, Rc, Rd, Re, Rf, Rg1, Rg2, Rg3, Rh1, Rh2, Ro, pseudoginsenoside F11, etc.
2. Sugars and polysaccharides Sucrose (8.0% yield) and ginseng trisaccharide have been separated from American ginseng. The average carbohydrate content of American ginseng in each production area was: reducing sugar 3.70%, oligosaccharide 15.40%, polysaccharide 49.74%, and total sugar 68.84%. 11.74% to 19.86% of water-soluble pectin can be extracted from American ginseng of various origins. Water-soluble pectin is composed of galacturonic acid, galactose, glucose, arabinose, xylose, rhamnose and a small amount of unknown sugars. The yield of hydrochloric acid-soluble pectin was 5.52%-9.62%. The yield of acid polysaccharide is 20.40%～29.45%.
3. Amino acids American ginseng is isolated from special amino acids – notoginseng, trypphane, 7 kinds of essential free amino acids, etc.
4. Fatty acids were extracted and isolated from American ginseng to identify caproic acid, heptanoic acid, octanoic acid, nonanoic acid, pentadecanoic acid, hexadecanoic acid, heptadecanoic acid, octadecenoic acid, octadecadienoic acid, 9, 12, 5 -Ocetatrienoic acid, 8-methyldecanoic acid.
5. Polyacetylene compounds are volatile, few of them, and have strong cytotoxic activity against leukemia cells (L1210). Three new cytotoxic polyacetylenes were isolated from American ginseng: PQ-1, PQ-2, PQ-3, and then three similar compounds were proposed, which are Panaquin-queeols1, 2, and 3 respectively.
6. Sterols have been isolated from American ginseng roots to obtain daucosterol, stigmastenol, stigmast-3,5-dien-7-one (stigmast-3,5-dien-7-one) one) etc.
7. Other ingredients include VA, VB, VB2, VB6, enzymes, volatile oils, such as β-farnesene, active polyphenols, such as caffeic acid and chlorogenic acid.
(1) Ginsenoside Rb1: molecular formula C54H92O23, molecular weight 1109.26. White powder (ethanol-butanol), mp197℃～198℃, [α]D22+12.42°(c=0.91, methanol). (2) Ginsenoside Rb2: molecular formula C53H90O22, molecular weight 1079.24. mp200℃～203℃, [α]D22+3.05°(c=0.98, methanol). Ginsenoside Rc: molecular formula C53H90O22, molecular weight 1079.24. White powder (ethanol-butanol), mp199℃～201℃, [α]D22+1.93°(c=1.03, methanol).
(3) Ginsenoside Rd: molecular formula C48H82O18, molecular weight 947.12. White powder (ethanol-ethyl acetate), mp206℃～209℃, [α]D22+19.38°(c=1.03, methanol). (4) Ginsenoside Re: molecular formula C48H82O18, molecular weight 947.12. Colorless needle crystals (5% ethanol), mp201℃～203℃, [α]D300°～-1.0°(c=1.00, methanol). (5) Ginsenoside Rf: molecular formula C42H72O14, molecular weight 801.00. White powder (acetone), mp197℃～198℃, [α]D30+6.99°(c=1.00, methanol).
(6) Ginsenoside Rg1: molecular formula C42H72O14, molecular weight 830.03. Colorless semi-crystalline substance (n-butanol-methyl ethyl ketone), mp194℃～195℃, [α]D19.5+32°(pyridine). Soluble in methanol, pyridine and hot acetone, slightly insoluble in ethyl acetate and chloroform.
(7) Ginsenoside Rg3: molecular formula C42H72O13, molecular weight 784. White crystal (dioxane), mp298℃～301℃. Insoluble in methanol, easily soluble in pyridine.
(8) Ginsenoside Rh1: molecular formula C36H62O9, molecular weight 638. White powder crystal (methanol), mp248℃～252℃.
(9) Ginsenoside RA0: molecular weight 1286. White needles (methanol), mp192℃～193℃.
(10) Pseudo ginsenoside F11: molecular formula C42H72O14. White powder, mp208℃～210℃, [α]D14-21.5°(c=1.77, methanol).

Benefits of American Ginseng Extract Powder

American Ginseng Extract Powder has many benefits to the human body, and the common benefits are as follows:

First, American Ginseng Extract Powder has a good blood sugar lowering effect for people with high blood sugar, which can avoid high blood sugar, blurred vision, or dizziness, headache and other physical problems.

Second, American Ginseng Extract Powder has a good analgesic effect and can effectively improve physical problems such as joint pain or muscle pain. In clinical practice, there are also many medicines based on American ginseng extract.

Third, the benefits of American Ginseng Extract Powder to the human body are that it has a good anti-fatigue effect, which is very suitable for office workers to improve the fatigue state that office workers are prone to.

Fourth, American Ginseng Extract Powder has a good effect of enhancing human immunity, which can make the human body’s anti-virus ability become stronger, prevent viruses from invading the body and cause physical diseases,

Fifth, American Ginseng Extract Powder has the effect of increasing body metabolism, especially accelerating fat metabolism, so it can also promote weight loss.

American Ginseng Extract PowderIdentification

Character identification
The main root is long conical, fusiform or cylindrical, 3 to 12 cm long and 0.4 to 2 cm in diameter. The reed head is removed or remains, the appearance is light gray-brown or yellow-white, relatively plump, with fine and shallow longitudinal wrinkles, those who are slightly thinner have deeper longitudinal wrinkles, obvious horizontal rings, and linear embolization scars. There are often one or several lateral roots in the middle and lower parts of the main root, which are forked and branched, and are often broken or only stubbed. The quality is firm, the fracture surface is relatively flat, slightly powdery, powdery white or light yellow-brown, the color of the ring pattern (cambium) is slightly darker, and the skin has dark brown spots. The gas is slight and specific, and the taste is slightly bitter and sweet. The shape of “wild ginseng” is mostly uneven, the main root is short cylindrical or short conical, and the surface ring pattern is dense and clear. The main root of “Ginseng” is long cone-shaped, with few and sparse surface rings, more verrucous fibrous root scars, and few or no lateral roots.

Microscopic identification
Cross section of main root: the cork layer consists of several columns of cork cells, yellowish-brown. The cortex is narrow, and some cells contain calcium oxalate clusters. There are often fissures on the outer side of the phloem, with scattered resin canals containing yellow-brown secretions. The cambium is obvious. The xylem vessels are scattered singly or in several clusters, arranged intermittently in a radial pattern. Parenchyma cells are filled with starch granules.

Physical and chemical identification
Take 0.5g of powder, add appropriate amount of water to moisten, add 2ml of n-butanol saturated with water, ultrasonically treat for 20min, take the supernatant and evaporate to dryness, dissolve the residue in 1ml of methanol, and use it as the test solution. In addition, 0.5 g of American ginseng reference medicinal material and 0.5 g of ginseng reference medicinal material were taken, and the same method was used to prepare American ginseng reference medicinal material solution and ginseng reference medicinal material reference solution. Separately prepared ginsenoside-Rb1, -Re, -Rg1 reference substance methanol solution (1mg/ml). Take 5 μl of each of the above 6 solutions, and spot them on the same silica gel G thin-layer plate. 10)] Place the lower layer solution at 5～10℃ for 12h to develop, spray with 10% sulfuric acid ethanol solution, bake at 105℃ until the spots are clear, inspect under sunlight and ultraviolet light (365nm). The chromatogram of the test substance shows spots of the same color in the corresponding positions of the chromatogram of the reference medicinal material of American ginseng and the chromatogram of the reference substance, which is different from the chromatogram of the reference medicinal material of ginseng.

UV spectral identification
Take an appropriate amount of the sample powder, use a Soxhlet extractor to degreasing with ether in a water bath for 2 hours, and extract the residue with methanol under reflux for several times. The n-butanol extract was recovered to dryness under reduced pressure, and dissolved in methanol to form a methanol solution containing 3 mg of the original medicinal material per 1 ml. Draw 1.5ml of sample solution, add 0.6ml of concentrated sulfuric acid, shake well, heat on a water bath at 80°C for 60min, add ethanol to 10ml, and measure its ultraviolet spectrum. Results American ginseng had the maximum absorption peak at the wavelength of 275±1nm.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.