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Acido Linoleico Conjugado CAS 2420-56-6

Molecular Formula: C18H32O2

Formula Weight: 280.45

ZSpharmac: Acido Linoleico Conjugado Supplier

Product Name: Acido Linoleico Conjugado
CAS No: 2420-56-6
Purity: 99%

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Basic Info

Product Name:Acido Linoleico Conjugado
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colourless Oil
EINECS No.:607-342-5
Provide:Acido Linoleico Conjugado MSDS;
Acido Linoleico Conjugado COA

What is Acido Linoleico Conjugado?

Conjugated linoleic acid (CLA) is octadecadienoic acid including cis- or trans-conjugated double bonds. It is a general term for a team of positional as well as conformational isomers of linoleic acid. It has many functions such as swelling advancement, fat burning, anti-atherosclerosis, renovation of immune function, decreased cholesterol, as well as growth promo. It is a new sort of helpful oil.

Acido Linoleico Conjugado Property

Boiling point 377.7±11.0 °C(Predicted)
density 0.911±0.06 g/cm3(Predicted)
Fp 14℃
storage temp. −20°C
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO, Methanol (Slightly)
form Oil
color Colourless


Physiological Functions of Acido Linoleico Conjugado

1. Anticancer impact Acido Linoleico Conjugado can inhibit the spreading, nuclear division, throng development and DNA synthesis of human stomach adenocarcinoma cells (SGC-7901), as well as can induce the distinction of SGC-7901 cells.

2. Anti-atherosclerosis High blood cholesterol concentration is the major reason for atherosclerosis. CLA can successfully hinder the incident of arteriosclerosis as well as likewise set off partial regression of the formed arteriosclerosis.

3. Improve the body’s resistance Acido Linoleico Conjugado can promote cellular division, protect against muscular tissue wear and tear, as well as delay the decline of the body’s resistance. CLA is involved in the plan of the immune system, boosting the blast-like adjustment of lymphocytes triggered by mitogens, the virulence of lymphocytes and the lethality of macrophages.

4. Enhance meat high quality Acido Linoleico Conjugado can efficiently hinder the oxidation of myosin during icy storage area of pork, nonetheless has no result on meat shade.

5. Join fat decomposition and likewise metabolic process CLA can lower body fat, particularly abdominal fat, yet body weight stays the exact same. Acido Linoleico Conjugado can prevent fat deposition and likewise climb lean meat percent, which is due to the restraint of fat synthesis and increased lipolysis in fat. CLA decreases body fat by reducing feed consumption, increasing metabolic price and also reducing nocturnal respiration.

6. Increase bone tissue metabolic procedure Acido Linoleico Conjugado can advertise the department along with regrowth of bone cells, advertise the synthesis of cartilage material tissue cells and likewise the deposition of minerals in bone cells, along with has a favorable outcome on bone wellness. This could be the outcome of altering the emphasis of PGE2. Severe focus of PGE2 can avoid the synthesis of bone, while CLA can effectively decrease the emphasis of PGE2, therefore promoting the formation of bone. 7. Anti-mildew outcome The sodium salt and also potassium salt of CLA can prevent the development of mold, and likewise have no harmful and side effects. The residence is rather protected as well as likewise has no ceiling of use. It can be made use of in food, cosmetics and also numerous other markets, as well as can be utilized as a substitute for salt benzoate.

Source of Acido Linoleico Conjugado

1. Natural event All-natural Acido Linoleico Conjugado mostly exists in milk fat and also meat items of rumen animals such as livestock as well as sheep, and also the web content of milk fat per gram arrays from 2 to 25 mg, as well as the content of CLA raises with the age of cows. The formation of CLA is because of the conversion of linoleic acid to CLA by the anaerobic butyrifibriolyticus linoleic acid isomerase in the gut of ruminants, mostly to the naturally active cis-9, trans-11 isomer. CLA is likewise existing in percentages in the cells, blood and also body fluids of various other pets. CLA is likewise discovered in human milk.

2. Fabricated synthesis CLA can be synthesized by base-catalyzed isomerization reaction with linoleic acid or vegetable oil rich in linoleic acid as substrate. The initially artificially manufactured Acido Linoleico Conjugado is a mix of different isomers, primarily having cis-trans, trans-cis isomers and also a percentage of cis-cis, trans-trans isomers. The improved synthesis procedure can make CLA more purified, the content of cis-9, trans-11 as well as tRNAs-10, cis-12 isomers exceeds 50%, and the non-CLA parts are less than 1%. Currently, man-made synthesis primarily has the complying with artificial approaches.

( 1) Alkaline isomerization of linoleic acid utilizes natural grease as resources, under the problems of KOH as catalyst as well as propylene glycol as solvent, mixed and refluxed in the presence of nitrogen security and also heating, after reflux, include aqueous solution, and adjust the pH worth with hydrochloric acid, drawn out with n-hexane, the essence was washed with brine, dried with magnesium sulfate, as well as finally concentrated under reduced pressure to obtain a combination of conjugated linoleic acid. This alkaline isomerization approach has a basic process, and also the gotten product is safe and also simple to take care of, so it is widely utilized and also appropriate for the production of conjugated linoleic acid from veggie oils abundant in linoleic acid, such as soybean oil, red Flower oil, cottonseed oil, corn oil, etc, as well as their products can be widely used in food processing.

( 2) Dehydration of oleic acid allyl alcohol Allyl oleic acid is oleic acid generated peroxide by light, as well as after being reduced, 8-hydroxyl or 11-hydroxyl oleic acid allyl alcohol is obtained. Allyl oleic acid is an additional item of oleic acid, which exists in natural foods as well as can be dried out into conjugated linoleic acid under acid-catalyzed (BF3, HCl) conditions. The methylation of conjugated linoleic acid was carried out by using the specificity of G. candidum lipase. Because the lipase has specificity for cis-9, trans-11-octadecadienoic acid, it can be executed Methyl esterification has no result on trans-10, cis-12-octadecadienoic acid, and also molecular distillation innovation can get cis-9, trans-11-octadecadienoic acid with greater pureness.

( 3) Esterification technique Castor oil is dissolved in dichloromethane as well as methanol option, as well as esterification reaction takes place under the condition of salt as well as reflux to produce ricinoleic acid methyl ester. The apart as well as cleansed ricinoleic acid methyl ester can react with 12-methylsulfonyl chloride to generate 12-methylsulfoxymethyl oleate, as well as the toluene option of 12-methylsulfoxymethyl oleate remains in DBU (1,8 -diazabicyclo [5.4.0] undecane-7-ene) under the catalysis of reflux, the total digestion product gotten is generally cis-9, trans-11-octadecadienoic acid methyl ester. Acido Linoleico Conjugado items with higher purity can be obtained by using urea for splitting up and also purification.

( 4) Microbial fermentation Microbial fermentation is making use of linoleic acid isomerase in bacteria to transform linoleic acid right into conjugated linoleic acid. From the research study results that have been acquired until now, lactic acid microorganisms are optimal stress, especially acidophilic lactic acid bacteria can successfully convert linoleic acid or glycerol linoleate into conjugated linoleic acid. Lactic acid germs include linoleic acid isomerase, and its action site is the C12 double bond of fat as opposed to the C9 double bond, to make sure that it can convert linoleic acid right into cis-9, trans-11-octadecadienoic acid, yet not various other isomers, the gotten Acido Linoleico Conjugado can be straight extracted from the cell culture fluid.

About Products:
If you need Acido Linoleico Conjugado, the cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Acido Linoleico Conjugado, our company, ZSpharmac will provide Acido Linoleico Conjugado raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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