Zhishang Chemical

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Zhishang Chemical

Acido Linoleico CAS 60-33-3

Molecular Formula: C18H32O2

Formula Weight: 280.45

ZSpharmac: Acido Linoleico Supplier

Product Name: Acido Linoleico
CAS No: 60-33-3
Purity: 99%

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Basic Info

Product Name:Acido Linoleico
Other Names:Linoleic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear yellow Liquid
EINECS No.:200-470-9
Storage:Store Below +30°C.
Provide:Acido Linoleico MSDS;
Acido Linoleico COA

What is Acido Linoleico?

α-linoleic acid is a colorless to pale yellow oily liquid at room temperature, and is easily oxidized in air. Melting point (°C): -12, boiling point (°C): 230 (2.13kPa). Acido Linoleico is a fatty acid that cannot be synthesized by the human body, or the amount of synthesis is far from meeting the needs, called essential fatty acids. Both Acido Linoleico and alpha-linolenic acid are nutritionally well-defined essential fatty acids. They are of great significance to human health. But this is not to say that supplementing Acido Linoleico blindly and increasing the intake of Acido Linoleico will have positive effects on human health. On the contrary, when the intake ratio of linoleic acid to α-linolenic acid is much higher than 4:1, not only will it not bring us health, but it will cause us to have hyperlipidemia, hyperviscosity and the resulting other diseases that emerged.

Acido Linoleico Property

Melting point 

-5 °C (lit.)

Boiling point 

229-230 °C/16 mmHg (lit.)


0.902 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.466(lit.)


>230 °F

storage temp. 

Store below +30°C.


NaOH: soluble1M




4.77(at 25℃)


Clear yellow

Water Solubility 




Acido Linoleico Uses

  1. Acido Linoleico is utilized in cosmetics as an emollient and also thickener. In addition, research studies have actually shown it to be reliable as a skin restorative, antioxidant as well as skin soothing agent.
  2. Acido Linoleico is a lipid-lowering medicine for the treatment and also prevention of atherosclerosis. Normally no adverse effects. Stomach responses such as nausea or vomiting, vomiting, and looseness of the bowels may take place after long-lasting management, which will progressively disappear after continued administration.
  3. Acido Linoleico Important and fats in human and animal nutrition. Both animals as well as plants have desaturase, which can dehydrogenate saturated fatty acids to create unsaturated fats with a double bond such as oleic acid, but only plant cells have the capability to additional dehydrogenate oleic acid right into linoleic acid. Acido Linoleico is a precursor to synthetic pet prostaglandins. The absence of fatty acids such as linolenic acid in Acido Linoleico can create stunted growth, skin as well as kidney damage, and infertility in animals. Acido Linoleico can integrate with cholesterol to form an ester, as well as can further advertise the deterioration of cholesterol into bile acid, which is then eliminated from the body, and also has the effect of decreasing triglycerides. It is utilized in medication as the raw material of drugs for the avoidance and therapy of atherosclerosis (such as Yishouning, Maitong, and so on). In industry, linoleic acid is used in the production of paints as well as inks and the preparation of amides, polyesters, polyureas, and so on. Salt or potassium linoleic acid is among the parts of soap and also can be made use of as a surfactant such as an emulsifier. Acido Linoleico is non-toxic.
  4. The metabolites of Acido Linoleico in the human body are necessary nutrients for the mind as well as have an excellent preventive effect on cardio and cerebrovascular illness.

Acido Linoleico Production Method

Method 1: Using corn oil as raw material
Preparation of Acido Linoleico Crude Product Measure clarified corn oil, gradually add 200g/L sodium hydroxide solution, stir while adding, continue to stir for 15min after adding, stand at 25-40°C for saponification for 48h, take out the saponified product, and use Pound it into pieces with a wooden shovel, slowly add 45%-50% sulfuric acid, and acidify at 30-40°C for 7 hours to obtain the crude product of Acido Linoleico.
Corn Germ Oil [NaOH,25-40℃]→Saponified [H2SO4,30-40℃]→Acido Linoleico crude product
Preparation of finished linoleic acid product Take the crude product in a separatory funnel, add 2 times the volume of tap water at 30°C, shake, separate the water layer, repeat this 5-6 times, then wash with warm distilled water until there is no sulfate , to obtain linoleic acid solution. Add 100g/L anhydrous sodium sulfate, shake well, and let stand at 25-30°C for 48-96h to obtain the refined product. Suction filter the refined product, and the filtrate is the finished product of linoleic acid.
Acido Linoleico crude product [H2O, 30℃] → Acido Linoleico liquid [anhydrous Na2SO4, 25℃] → linoleic acid refined product [suction filtration] → Acido Linoleico finished product

Method 2: Using soybean oil foot as raw material
Preparation of soap slurry Take soybean oil scraps, heat to about 90°C, add a little sodium hydroxide solution of 1/10-1/7 times the amount, continue heating for 15 minutes, then add the remaining lye, until the phenolphthalein indicator turns purple , and then heated and boiled for 2-3h to obtain saponified matter. Add 1/20-1/10 times the amount of industrial sodium chloride to the saponified product twice, heat until the soap slurry does not stick to the knife when sampling with the spatula, and stop when there is obvious black water precipitation, and then heat for 1-2h, Insulate and stand for 3 hours, pump out the lower layer of black water to obtain soap slurry.
Refined oil offal [NaOH,>90℃]→saponified liquid[NaCl]→soap slurry
Preparation of black fatty acid Add the waste acid water extracted from the first batch of acidification to the soap slurry, heat it with steam for 30 minutes, let it stand for 1 hour, draw out the waste water, and then slowly add 1/10-1/7 times the amount of concentrated sulfuric acid to When stratification occurs, let stand for 1 hour, take out the waste acid water in the lower layer, and reserve it for the next batch of acidification to obtain the acidification solution. Add 3 times the amount of clear water to the acidification solution, heat it with steam to above 80°C for 20 minutes, let it stand for 30 minutes, pump out the waste water, and repeat the operation 3-4 times until the pH value of the waste water is 6-7 to obtain black fatty acid.
Soap slurry [H2SO4]→acidified solution[H2O,>80℃]→black fatty acid
Preparation of Acido Linoleico Crude Product Heat black fatty acid to about 105°C, suck it into the distillation tower in batches, and distill under reduced pressure. 190-200°C. For 1.5 hours each time, steam the mixed fatty acids and put the black feet once. Freeze the mixed fatty acid to about 0-2°C, take it out and put it in a wet cloth bag and press it with a hydraulic press, gradually increase the pressure to 14.71MPa, press for 10-12 hours, the extruded liquid is crude linoleic acid, and the solid matter left in the bag For stearic acid.

Preparation of Acido Linoleico Finished Product Heat the crude linoleic acid to 100°C, suck it into the distillation tower, feed 90kg each time, the temperature of the biphenyl furnace is 265-275°C, the pressure is 19.6-49kPa, the vacuum of the distillation tower is above 99.75kPa, and the gas phase temperature is 185 -200°C, the distillate is Acido Linoleico.
Crude linoleic acid [185-200°C, 100kpa]→Acido Linoleico finished product.

Acido Linoleico Efficacy and Function

Cardiovascular protection
The main function of Acido Linoleico is to protect the cardiovascular and cerebrovascular. This substance can soften the cardiovascular and cerebrovascular of human beings and accelerate the blood circulation in the body. It can lower blood pressure and blood lipids and speed up the metabolism of the human body. Delay aging, so this substance has the title of blood vessel scavenger in life.

Prevent arteriosclerosis
Acido Linoleico is a fatty acid that is necessary for the normal work of various organs in the human body. It can speed up the metabolism and decomposition of fat in the human body, and can also reduce the accumulation of cholesterol on the blood vessel wall of the human body. It can increase the elasticity of blood vessels and prevent the aging and rigidity of blood vessels. Absorbing an appropriate amount of linoleic acid can effectively prevent the occurrence of arteriosclerosis.

After the human body absorbs rich Acido Linoleico, it can play an important role in weight loss, because this substance can reduce the amount of fat in the human body, accelerate the decomposition and metabolism of excess fat in the body, and increase the density of human muscle. Prevent obesity and make people taller and stronger. In addition, Acido Linoleico can also improve human immunity, promote bone development, improve memory, and prevent brain function degeneration.

About Products:
If you need Linoleic acid as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Linoleic acid manufacturer and supplier, ZSpharmac will provide Linoleic acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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