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Acetyl Tetrapeptide-5 CAS 820959-17-9

Molecular Formula: C20H28N8O7

Formula Weight: 492.49

ZSpharmac: Acetyl Tetrapeptide-5 Supplier

Product Name: Acetyl Tetrapeptide-5
CAS No: 820959-17-9
Purity: 99%

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Basic Info

Product Name:Acetyl Tetrapeptide-5
Other Names: N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:A Crystalline Solid
EINECS No.:1312995-182-4
Provide:Acetyl Tetrapeptide-5 MSDS;
Acetyl Tetrapeptide-5 COA

Function of Acetyl Tetrapeptide-5

Acetyl tetrapeptide-5, additionally called eye serine peptide, can get rid of edema and improve skin elasticity as well as smoothness. Prevents glycation, reduces bags under the eyes and battles creases. Dior, SK-II, as well as Lancome are all added for anti-wrinkle. Acetyl Tetrapeptide-5 is considered a humectant or moisture taking in agent that can help in reducing eye puffiness as well as boost skin flexibility and general smoothness. It makes use of the hygroscopic residential or business properties of this material to attract dampness from deep within the skin to the outermost layer of the skin (the stratum corneum), therefore minimizing puffiness. Its moisturizing homes make it reliable for treating xeroderma (unusually completely dry skin).

Acetyl Tetrapeptide-5 Property

Boiling point 1237.3±65.0 °C(Predicted)
density 1.443
storage temp. 2-8°C
solubility PBS (pH 7.2): 10 mg/ml
form A crystalline solid

Acetyl Tetrapeptide-5 Application

For the prep work of a firming eye cream. The firming eye lotion of the present moment advancement includes high-efficiency nutritional energetic components such as acetyl tetrapeptide-5, purslane essence, panthenol, vitamin E, ginger root eliminate, bisabolol, coenzyme Q10, salt hyaluronate, and a lot more.Promote cell differentiation and additionally collagen synthesis to enhance skin elasticity; it can additionally advertise the metabolic rate of the stratum corneum of the skin, making the skin softer as well as smoother, in addition to efficiently promoting skin regrowth, decreasing creases and likewise tightening up the skin; at the same time, polysilicone Alkane-11 can quickly smooth the fine lines of the eye skin along with tighten up the skin around the eyes.

Preparation of Acetyl Tetrapeptide-5

1. For the preparation of a firming eye cream

CN201510120523.4 offers a firming eye lotion, which can immediately smooth the fine lines of the eye skin as well as tighten the skin around the eyes. A firming eye lotion, characterized in that it includes the following parts in weight percent: polysiloxane-11 5.0% -27.0%, cyclomethicone 2% -10%, butylene glycol 1%- 6%, glycerin 1% -6%, dioctyl carbonate 1% -8%, trimethylsiloxysilicate 1.5-3%, phenyl polytrimethicone 0.5% -4%, poly Dimethicone 1.0% -2.0%, Cyclopentasiloxane 0.5% -1.0%, Arachidyl Glucoside 1.5% -3.0%, Glyceryl Stearate 0.5% -1.0%, PEG- 100 stearate 0.5% -1.0%, cetearyl alcohol 0.5% -1.5%, acetyl tetrapeptide-5 0.5% -1.5%, purslane extract 0.05% -2.5%, panthenol 0.1%- 1.5%, vitamin E 0.5% -1.5%, ginger origin extract 0.05% -0.30%, bisabolol 0.01% -0.5%, phenoxyethanol 0.1% -0.5%, methylparaben 0.01% -0.25%, Acrylates/C10 -30 Alkyl Acrylate Crosspolymer 0.1% -0.25%, Propylparaben 0.01% -0.15%, Aminomethyl Propanol 0.06% -0.15%, Coenzyme Q10 0.01% -0.20%, sodium hyaluronate 0.01-0.30%, significance 0.01% -0.0.30%, disodium EDTA 0.01% -0.1%, deionized water to 100%.

Beneficial effects: the firming eye cream of the here and now invention contains high-efficiency nutritional ingredients such as acetyl tetrapeptide-5, purslane extract, panthenol, vitamin E, ginger origin extract, bisabolol, coenzyme Q10, and also sodium hyaluronate, can boost skin elasticity by promoting cell distinction as well as collagen synthesis; it can likewise promote the metabolism of the stratum corneum, make the skin softer and smoother, and successfully promote skin regeneration, minimize wrinkles as well as tighten up the skin; at the same time Polysiloxane-11 has the ability to promptly smooth the fine lines of the eye skin as well as tighten the skin around the eyes.

2. Utilized to prepare a polypeptide essence for eliminating inflammation and blood streaks

CN201710000327.2 recommends a polypeptide essence for eliminating inflammation and also blood streaks. The polypeptide anti-redness significance makes use of a variety of appeal peptides as the major energetic ingredients to put in a collaborating impact, enhance the flexibility of veins, decrease the permeability of capillaries, eliminate inflammation, diminish and also broaden veins, and restore regular microcirculation. Play an excellent soreness dispelling result. In order to achieve the above object, today development takes on the following technological remedies:

A polypeptide cosmetic for eliminating redness as well as bloodshot essence, comprising the following elements by weight percentage:
Nonapeptide-1 1|10%.

Decapeptide-4 1|10%.

Angiotensin 1|10%.

Hexapeptide-9 1|10%.

Acetyl Tetrapeptide-5 1-10%.

2% Carbomer 940 1|10%.

Aloe Vera Essence 1|5%.

Xanthan gum tissue 0.01|0.1%.

Glycerin 1|5%.

Butanediol 1|5%.

Hyaluronic acid 0.01|0.1%.

Methylparaben 0.01|0.2%.

Genma 0.01|0.2%.

water balance.

The preparation approach consists of the following steps:.

1) Include water, 2% carbomer 940, aloe vera remove, xanthan periodontal, glycerin, butylene glycol, hyaluronic acid, methylparaben, as well as Gemma right into the response tank, begin mixing, as well as warmth to 75|80 ℃, stir as well as spread uniformly;.

2) Remain to stir and also cool down to below 40 ° C, add nonapeptide-1, decapeptide-4, angiotensin, hexapeptide-9, acetyl tetrapeptide-5, right into the reaction storage tank, co-opt for 2-3 mins, Mix to dissolve completely, end.

In today innovation, acetyl tetrapeptide-5: can improve inadequate lymphatic blood circulation as well as extreme capillary leaks in the structure, prevent glycation, eliminate edema, and boost skin flexibility and smoothness. It has the adhering to advantageous effects: 1) This product has a high content of beauty peptide components, which can successfully eliminate face inflammation, promote skin metabolism, brighten as well as firm the skin, make the skin moist, smooth, flexible, as well as boost the youthful vigor of the skin. 2) The polypeptide essence for removing red blood touches of the here and now innovation is risk-free and also secure, has good leaks in the structure as well as is easy to take in. 3) After 2 week of continuous use the peptide anti-redness significance, it can effectively tighten up skin capillaries and decrease face redness.

3. Utilized to prepare a polypeptide anti-radiation significance.

CN201710000339.5 recommends a polypeptide anti-radiation essence. The peptide anti-radiation significance uses a selection of appeal peptides as the main energetic ingredients, and exerts a synergistic impact to block, safeguard and also repair light radiation and also electromagnetic radiation. In order to accomplish the above item, the here and now development embraces the complying with technological solutions:.

A polypeptide anti-radiation significance cosmetic, consisting of the complying with parts by weight percentage:.

Tripeptide-33 1|10%.

Acetyl Hexapeptide-49 1|10%.

Acetyl Tetrapeptide-5 1-10%.

Nonapeptide-1 1|8%.

Decapeptide-4 1|8%.

2% Carbomer 940 1|10%.

Aloe Vera Remove 1|5%.

Xanthan periodontal 0.01|0.1%.

Glycerin 1|5%.

Butanediol 1|5%.

Hyaluronic acid 0.01|0.1%.

Methylparaben 0.01|0.2%.

Genma 0.01|0.2%.

water equilibrium.

The prep work method makes up the adhering to steps:.

1) Add water, 2% carbomer 940, aloe vera remove, xanthan periodontal, glycerin, butylene glycol, hyaluronic acid, methylparaben, as well as Gemma into the response storage tank, begin mixing, as well as heat to 75|80 ℃, stir as well as disperse equally;.

2) Continue to stir and cool down to listed below 40 ° C, include tripeptide-33, acetyl hexapeptide-49, acetyl tetrapeptide-5, nonapeptide-1, decapeptide-4 into the response tank, co-opt 2-3 Minutes, mix to dissolve entirely, end.

Compared with the existing products, the essence of the here and now development has the adhering to beneficial effects: 1) This item has a high web content of aesthetic polypeptide parts, can successfully resist radiation, promote skin metabolic rate, brighten and also firm the skin, and also make the skin moist, smooth and flexible. Boosts skin youthfulness. 2) The polypeptide anti-radiation significance of the here and now innovation is secure and steady, has good permeability, is easy to soak up, as well as the face is rejuvenating and non-sticky after usage; and the prep work method is straightforward, the process is steady, as well as can be promoted and applied.

About Products:
If you need Acetyl Tetrapeptide-5, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Acetyl Tetrapeptide-5, ZSpharmac will provide Acetyl Tetrapeptide-5 raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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