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Acetamide CAS 60-35-5

Molecular Formula: C2H5NO

Formula Weight: 59.07

ZSpharmac: Acetamide Cosmetic Raw Material Suppliers

Product Name: Acetamide
CAS No: 60-35-5
Purity: 99%

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Basic Info

Product Name:Acetamide
Other Names:Acetamidum
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystals
EINECS No.:200-473-5
Storage:Store Below +30°C
Provide:Acetamide MSDS;
Acetamide COA

What is Acetamide?

Ethanolamine EA is the most essential item among amino alcohols, including monoethanolamine MEA, Diethanolamine SigmaDEA as well as triethanolamine TEA. Ethanolamine is an important organic intermediate, extensively utilized in surfactants, artificial detergents, petroleum additives, artificial resins as well as rubber plasticizers, accelerators, vulcanizing agents and lathering representatives, along with gas filtration, liquid antifreeze, Printing as well as dyeing, medication, pesticide, building and construction, army and also various other areas. Many downstream items of ethanolamine are essential great chemical intermediates, and also they are additionally one of the most sought-after chemical items in our nation. Consequently, the application and also growth of ethanolamine has been enhanced to meet the requirements of domestic great chemicals on the one hand, as well as advertise the quick growth of the ethanolamine market on the other hand.

Diethanolamine Sigma, additionally referred to as bishydroxyethylamine, 2,2′-iminobisethanol, is a white crystal or anemic liquid with solid hygroscopicity. It is easily soluble in water, methanol, ethanol, acetone and also benzene, as well as its solubility in benzene (g/100g) at 25 ° C is 4.2 as well as 0.8 in ether. Its usages are: gas detoxifying agent, which can soak up acid gases in the gas, such as carbon dioxide, hydrogen sulfide, sulfur dioxide, and so on. The “Benfield” option used in the artificial ammonia market is generally made up of this item; it is additionally utilized as an emulsifier., lubricating substances, shampoos, thickeners, etc; natural synthesis intermediates for the production of detergent resources, preservatives and day-to-day chemicals (such as surfactants); synthesis of morpholine.

Acetamide Property

Melting point 78-80 °C(lit.)
Boiling point 221 °C(lit.)
density 1.159
vapor pressure 1 mm Hg ( 65 °C)
refractive index 1.4274
Fp 220-222°C
storage temp. Store below +30°C.
solubility H2O: 0.5 g/mL, Hazen ≤50
pka0.63(at 25℃)
form Crystals
color White
OdorMousy odor
Water Solubility 2000 g/L (20 ºC)


Acetamide Uses

  1. Acetamide is primarily used as a natural solvent, as well as can additionally be made use of as a plasticizer and also peroxide stabilizer. It is taken advantage of as an antacid in cosmetic production and likewise is likewise taken advantage of in the prep work of resting tablets, chemicals, etc.
  2. Acetamide functions as an exceptional solvent for several not natural as well as natural materials when defrosted. Organic Synthesis. Include solvent. stabilizer. Plasticizer. Alcohol denaturant.
    Acetamide has a high dielectric constant, is a superb solvent for lots of organic as well as likewise not natural substances, in addition to is extensively used in various sectors. It can be used as a solubilizer when some compounds with low water solubility are liquified in water. As an example, it is used as a solvent as well as likewise solubilizer for dyes in the fiber field, along with it is used as a solvent in the synthesis of chloramphenicol along with various other prescription antibiotics.
  3. Acetamide is a little alkaline and can be made use of as an antacid in varnishes, explosives and also cosmetics. Acetamide is hygroscopic in addition to can be utilized as a moistening rep for dyeing; it can furthermore be made use of as a plasticizer for plastics. N-haloacetamide developed by chlorination or bromination of acetamide is a halogenating reagent for natural synthesis. Acetamide is furthermore a resources for the manufacture of drugs as well as fungicides. Acetamide is the antidote for poisoning induced by the organofluorine chemical pesticide-fluoroacetamide. The device of action is that the chemical structure of this item appears like that of fluoroacetamide, as well as it can compete with acetamidase, to make sure that fluoroacetamide does not develop fluoroacetic acid, consequently eliminating the latter’s dangerous result on the tricarboxylic cycle in addition to attaining the function of cleaning.

Acetamide Production Methods

Glacial acetic acid responds with ammonia to generate ammonium acetate, which is after that thermally dried to acquire acetamide, which is then crystallized and divided to get the ended up item. Basic material usage quota: acetic acid (99%) 1700kg/t, fluid ammonia (99%) 750kg/t. Research laboratory synthesis can be performed according to the complying with steps. Place 3kg of antarctic acetic acid right into a 5L flask and also include ammonium carbonate matching to 400g of ammonia. The flask is outfitted with a high-efficiency fractionating column, condenser and also receiver. Heat the response combination till it steams slowly, as well as adjust the heating to ensure that the distillation rate does not surpass 180 mg/h until the top temperature level reaches 110 ° C. Obtain 1400-1500ml of water as well as acetic acid blend. Adjustment the receiver, slowly enhance the heating, and continue purification at the exact same rate up until the leading temperature level rises to 140 ° C. 500-700ml of distillate was obtained, mostly acetic acid, which was reserved for the next feeding. Relocate the deposit right into a flask with a fractionating column as well as an air condenser, distill under regular pressure, and collect the portions prior to 210 ° C as well as 210-216 ° C respectively. The last is acetamide, considering 1150-1200g, and the former can also be distilled to recuperate part of the product, with a total weight of 1200-1250g, as well as a return of 87%-90%. Acetamide is typically refined by purification and also solvent recrystallization. Generally used solvents include acetone, benzene, ethyl acetate, methyl acetate, chloroform, dioxane or a mix of benzene and ethyl acetate. For instance, by recrystallizing 1kg of acetamide prepared by the above method with a combined solvent of 1L benzene as well as 300ml ethyl acetate, a colorless needle-like pure product can be gotten. Products obtained from commercial production have a purity of not less than 98% and a freezing point of not less than 76 ° C.

Acetamide Precautions

1. All clients infected by organofluorine substances such as fluoroacetamide as well as salt fluoroacetate, including those thought of poisoning, must be provided this item in time, despite whether they are sick or not, and also do not wait for the toxin examination results to avoid postponing the treatment opportunity. Appropriate dose should be offered early.

2. According to medical records, for patients with organofluorine substance poisoning, despite the training course of the condition, management of this product will certainly have a certain result. Early management can save lives and also regulate the beginning, while late administration can reduce sequelae. There are reports that management as late as 5 to 7 days after poisoning still has specific effects.

About Products:
If you need Acetamide as a cosmetic raw material, please contact our service staff directly and we will provide you with high-quality products at the best price.
Our company, as an experienced Acetamide manufacturer and supplier, ZSpharmac will provide Acetamide raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Acetamide Quotation