Zhishang Chemical

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Zhishang Chemical

4-Tert-Butylphenol CAS 98-54-4

Molecular Formula: C10H14O

Formula Weight: 150.22

ZSpharmac: 4-Tert-Butylphenol Supplier

Product Name: 4-Tert-Butylphenol
CAS No: 98-54-4
Purity: 99%

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Basic Info

Product Name:4-Tert-Butylphenol
Other Names:P-Tert-Butylphenol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Light Beige Flakes or Pastilles
EINECS No.:202-679-0
Storage:Store Below +30°C.
Provide:4-Tert-Butylphenol MSDS;
4-Tert-Butylphenol COA

What is 4-Tert-Butylphenol?

4-tert-butylphenol is found in herbs and spices. 4-tert-butylphenol is present in oregano. 4-tert-butylphenol is a flavor component. 4-tert-butylphenol belongs to the class of cumenes. These are aromatic compounds that contain a prop-2-ylbenzene moiety.

4-Tert-Butylphenol Property

Melting point 

96-101 °C (lit.)

Boiling point 

236-238 °C (lit.)


0.908 g/mL at 25 °C (lit.)

vapor pressure 

1 mm Hg ( 70 °C)

refractive index 



113 °C

storage temp. 

Store below +30°C.


ethanol: soluble50mg/mL, clear, colorless


Flakes or Pastilles


10.23(at 25℃)


White to light beige

Specific Gravity



7 (10g/l, H2O, 20℃)

explosive limit


Water Solubility 

8.7 g/L (20 ºC)



4-Tert-Butylphenol Uses

  1. 4-tert-butylphenol is utilized as an artificial anti-oxidant.
  2. 4-tert-butylphenol is used in the synthesis of acaricide propargite in pesticides, as well as it is likewise the raw product of brand-new fungicide spiroxamine.
  3. 4-tert-butylphenol (1) is made use of in oil-soluble phenolic resins, which can be polycondensed with formaldehyde to obtain items with many usages. Include 10-15% of this item to chloroprene adhesives to obtain soluble materials. This sort of adhesive is primarily made use of in transportation, building and building and construction, civil engineering, along with shoemaking. (2) Used for modification of epoxy material along with xylene material; as polyvinyl chloride stabilizer, surfactant, as well as also ultraviolet absorber. (3) It has anti-oxidation properties as well as can be made use of as a stabilizer for rubber, soap, chlorinated hydrocarbons in addition to nitrocellulose. It is likewise the raw material of insect repellent (drug), acaricide clofenac (chemical), plant defense agent, spice, along with artificial material, along with can also be utilized as an additive for conditioner, solvent, shade, and paint. It can additionally be made use of as an element of demulsifiers for oilfields and ingredients for electric motor oils.
  4. 4-tert-butylphenol is used in ultraviolet absorbers, pesticides, anti-cracking representatives such as rubber and also layers, antioxidants, dispersants, lubes, cleaning agents, combustion help, stabilizers for styrene, additives for dyes and paints and industrial bug repellants.

4-Tert-Butylphenol Production Method

There are 3 kinds of procedure routes for p-tert-butylphenol.
( 1) Made from phenol as well as isobutylene.
Making use of cation exchange resin as a stimulant, accomplish catalytic alkylation in a fluidized bed at 80-140 ° C, the response content is 60%-70%, and the obtained blended tert-butylphenol is catalytically shifted into p-tert-butylphenol by taken care of bed, and after that rectified under reduced stress to separate excess phenol for recycling and get the product p-tert-butylphenol, with a yield of greater than 90% in regards to isobutylene.
( 2) It is gotten by reacting benzoic acid with 2,4,4-trimethyl-2-pentene (dimeric isobutylene).
In addition to getting p-tert-butylphenol in the reaction process, p-octylphenol is co-produced concurrently.
( 3) Acquired by the reaction of phenol and also tert-butanol.
Mix anhydrous aluminum trichloride with petroleum ether, gradually add phenol under mixing, cool down with ice water, then gradually include tert-butanol, stir for 15 minutes after adding, after that add anhydrous light weight aluminum trichloride in sets, as well as lastly Mix for 4-5 hours, gradually add to 1:1 hydrochloric acid, allow stand, separate the petroleum layer, remove the water layer with petroleum ether, integrate the oil ether remedy as well as clean with water, separate the cleansed water, recoup oil ether, and boil down under reduced pressure to obtain the finished item. When using this procedure for commercial manufacturing, the synthesis reaction is carried out at 145-150 ° C.

Ecological Information for 4-Tert-Butylphenol

The manufacturing and also use 4-Tert-Butylphenol as a chemical intermediate for numerous applications, specifically polycarbonate and additionally epoxy materials, as well as also as a plasticizer for cellulose acetate might result in its launch to the setup with different waste streams. Portions of unreacted 4-Tert-Butylphenol exist in polycarbonate in addition to epoxy materials, as well as p-tert-butylphenol has actually been detected in land fill leachate along with heater exhausts. If launched to air, the vapor tension at 25 ° C is 0.00919 mmHg, suggesting that p-tert-butylphenol will only exist in the ambience as a vapor. Gas phase-tert-butylphenol weakens cost-free radicals in the feel by reacting with photochemically created hydroxyl groups; the half-life of this response in air is approximated to be 9.5 hours. 4-tert-Butylphenol takes in at wavelengths > 290 nm and also therefore might go to danger to photolysis by straight sunshine. If released into dust, 4-Tert-Butylphenol is anticipated to be much less mobile based upon an approximated Koc of 1290. p-tert-Butylphenol has a pKa of 10.16, recommending that the material exists virtually entirely in the neutral type in the setting. Volatilization from moist soil surface areas is not expected to be a substantial fate based upon Henry’s law constant of 1.19X10-6 atm-cu m/mole procedure. Based upon its vapor stress, p-tert-butylphenol is not expected to volatilize from completely dry dirt surface areas. The results of the biodegradation testing exams indicated that p-tert-butylphenol could be quickly biodegraded by adjusted microorganisms at focus listed here the repressive effect. Consequently, biodegradation is expected to be a vital destiny process in dirt and also establishing. water. If launched into water, 4-Tert-Butylphenol is anticipated to adsorb to suspended solids along with sediment based upon the approximated Koc. Volatilization from water is expected to emerge according to the Henry’s Regulation constant for the compound. The approximated volatilization half-lives were 38 days as well as 279 days for the version river as well as likewise layout lake, especially. A BCF series of 20-120 shows reduced to moderate bioconcentration in water microbes. 4-tert-Butylphenol is secure against hydrolysis at pH 4, pH 7 as well as pH 9. Occupational direct exposure to 4-Tert-Butylphenol may take place with breathing as well as facial exposure to this substance in offices where 4-Tert-Butylphenol is produced or utilized. Tracking as well as additionally use information recommend that the basic population could be revealed to 4-Tert-Butylphenol with breathing of ambient air as well as facial direct exposure to customer items including p-tert-butylphenol. Potential client exposure via usage items consisting of phenolic or epoxy resins consisting of residual p-tert-butylphenol. Consumers might be revealed to p-tert-butylphenol from consuming alcohol water tanks covered with epoxy-based coverings or from pipelines. Customers may similarly be subjected to p-tert-butylphenol in polycarbonates used in food connect with items.

About Products:
If you need 4-Tert-Butylphenol as a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of 4-Tert-Butylphenol, ZSpharmac will provide 4-Tert-Butylphenol raw materials for customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get 4-Tert-Butylphenol Quotation