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4-Aminobenzoic Acid CAS 150-13-0

Molecular Formula: C7H7NO2

Formula Weight: 137.14

ZSpharmac: 4-Aminobenzoic Acid Supplement Supplier

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Product Name: 4-Aminobenzoic Acid
CAS No: 150-13-0
Purity: 99%

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Basic Info

Product Name:4-Aminobenzoic Acid
Other Names:P-Aminobenzoic Acid
CAS:150-13-0
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Light Yellow Crystalline Powder
EINECS No.:205-753-0
Storage:2-8°C
Provide:4-Aminobenzoic Acid MSDS;
4-Aminobenzoic Acid COA

What is 4-Aminobenzoic Acid?

4-Aminobenzoic Acid is an organic compound with the chemical formula C7H7NO2. It is a white crystalline solid that is soluble in hot water and organic solvents such as ethanol.

4-Aminobenzoic Acid Property

Melting point 187-189 °C(lit.)
Boiling point 251.96°C (rough estimate)
density 1.374 g/mL at 25 °C(lit.)
vapor pressure 0Pa at 25℃
refractive index 1.5323 (estimate)
Fp 250 °C
storage temp. 2-8°C
solubility 95% ethanol: soluble5%, clear to slightly hazy, colorless to yellow
form Crystalline Powder
pka2.50, 4.87(at 25℃)
color White to light yellow

 

4-Aminobenzoic Acid Uses

Pharmaceutical industry:
Drug synthesis intermediates: as important raw materials for the synthesis of many drugs, such as sulfa drugs (such drugs work by inhibiting bacterial folic acid synthesis, and p-aminobenzoic acid is one of the key raw materials in the synthesis process).
Local anesthetic: Benzocaine can be produced through esterification reaction, which is a commonly used local anesthetic used to relieve pain on the skin or mucous membranes.
Vitamin supplements: As a precursor for folic acid synthesis, it is indirectly used to produce vitamin B9 (folic acid) supplements, which is especially important for pregnant women and helps prevent fetal neural tube defects.

Cosmetics industry:
UV absorbers: Although less directly used in sunscreen products due to skin sensitivity issues, they may be used as auxiliary UV absorbing ingredients in specific formulations.

Dyestuff and Pigment Manufacturing:
Dye synthesis: p-aminobenzoic acid and its derivatives are key raw materials for the synthesis of certain azo dyes and fluorescent dyes, which are widely used in textiles, printing, biomarkers and other fields.

Agrichemicals:
Fungicides and herbicides: used as starting materials for the synthesis of certain pesticides, especially those compounds that work by interfering with the folate metabolism of microorganisms.

Scientific research and biotechnology:
Metabolic research: used as a research substrate for metabolic enzymes or as a tracer in metabolic tracking experiments.
Molecular Biology: Used as an auxiliary component in DNA sequencing and polymerase chain reaction (PCR) buffers to help maintain the stability of DNA.

Other industrial applications:
Resin and plastic additives: In some cases, used as resin modifiers or plastic stabilizers to improve product performance.

4-Aminobenzoic Acid Outstanding Applications in Cosmetics

UV protection:
Although not as widely used as other more common UV absorbers (such as oxybenzone, octisalicylate), para-aminobenzoic acid has been explored as a sunscreen product due to its ability to absorb certain wavelengths of UV rays (mainly the UVA range). active ingredients in. It helps prevent UV damage to the skin by absorbing UV energy and converting it into heat.

Formula auxiliary ingredients:
In some specific cosmetic formulas, para-aminobenzoic acid may not be used as the main UV filter, but may be used in combination with other sunscreen agents to broaden the sunscreen spectrum or enhance the overall stability of the formula. Its addition can help optimize the performance of the entire sun protection system.

Photosensitive protectant:
For some photosensitive skin care products, para-aminobenzoic acid may be used as an auxiliary ingredient to reduce photosensitivity reactions that other ingredients may cause and protect the skin from the adverse effects of environmental light sources.

4-Aminobenzoic Acid Features

Structural characteristics: Para-aminobenzoic acid is an aromatic compound whose molecule contains a benzene ring, a carboxylic acid group (-COOH) and an amino group (-NH2). This structure gives it good reactivity and versatility, making it a useful precursor for the synthesis of a variety of compounds.

Physical properties: It usually exists in the form of white monoclinic prisms, with a melting point of 188-189°C and a relative density of 1.374 (25/4°C). These physical properties are important in the selection of their handling and storage conditions.

Solubility: p-aminobenzoic acid is easily soluble in boiling water, soluble in alcohol, ether, ethyl acetate and glacial acetic acid, slightly soluble in cold water and benzene, and insoluble in non-polar solvents such as petroleum ether. This solubility characteristic affects its use in synthetic reactions and purification processes.

Chemical reactivity:
Acylation reaction: Its carboxyl group can participate in esterification or amidation reaction to generate the corresponding ester or amide derivatives.
Condensation reaction: Amino groups can participate in diazotization, coupling and other reactions to generate dyes or drug molecules.
Redox reaction: Under appropriate conditions, it can be oxidized or reduced to generate different derivatives for use in specific chemical synthesis pathways.
Biological activity: As an intermediate in the synthesis of folic acid, para-aminobenzoic acid plays an important role in organisms. It also acts as a UV absorber, although direct application in cosmetics is limited due to skin sensitivity issues.

Stability: It has certain stability to heat and light, but the specific stability depends on the storage conditions. Long-term exposure may affect its chemical properties and biological activity.

References

Sirota, T.V., Lyamina, N.E. & Weisfeld, L.I. The Antioxidant properties of para-Aminobenzoic acid and its sodium salt. BIOPHYSICS 62, 691–695 (2017). https://doi.org/10.1134/S0006350917050219

As a company specializing in the production and supply of 4-Aminobenzoic Acid raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the 4-Aminobenzoic Acid raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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