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Zhishang Chemical

3-Phenyl-1-Propanol CAS 122-97-4

Molecular Formula: C9H12O

Formula Weight: 136.19

ZSpharmac: 3-Phenyl-1-Propanol Supplier

Product Name: 3-Phenyl-1-Propanol
CAS No: 122-97-4
Purity: 99%

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Basic Info

Product Name:3-Phenyl-1-Propanol
Other Names:3-Phenyl-1-Propanol, 98%
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless Liquid
EINECS No.:204-587-6
Storage:Sealed in Dry,Room Temperature
Provide:3-Phenyl-1-Propanol MSDS;
3-Phenyl-1-Propanol COA

What is 3-Phenyl-1-Propanol?

3-Phenyl-1-Propanol has the aroma of hyacinth and mignonette, and has important application value. As an edible spice additive component, 3-Phenyl-1-Propanol is widely used in the fields of food, beverage and cosmetics. At the same time, 3-Phenyl-1-Propanol is also involved in the preparation of drugs, coatings, resins, etc., highlighting the Huge application potential.A

3-Phenyl-1-Propanol Property

Melting point 

−18 °C(lit.)

Boiling point 

119-121 °C12 mm Hg(lit.)


1.001 g/mL at 20 °C(lit.)

vapor pressure 

1.13-25Pa at 20-25℃

refractive index 

n20/D 1.526(lit.)


229 °F

storage temp. 

Sealed in dry,Room Temperature


0.1g/l insoluble






Clear colorless

Water Solubility 

10.3 g/L (20 ºC)



3-Phenyl-1-Propanol Uses

  1. 3-Phenyl-1-Propanol is used as a reagent in the synthesis of dihydrocinnamon-based cilnidipine, a powerful fragrant biotransformation product.
  2. 3-Phenyl-1-Propanol is utilized in the synthesis of spices and drugs. In the pharmaceutical market, it is the intermediate of the main skeletal muscle mass relaxant Dangpan Song. The item has a sweet flower fragrance and also a pleasant candied fruit fragrance, and also has a fresh as well as enjoyable melon and fruit scent after dilution. Natural items exist in strawberry, fungi balm, benzoin balm, tea, laurel leaf oil, etc my nation’s GB2760-86 specifies that it is temporarily enabled to utilize edible spices.
  3. 3-Phenyl-1-Propanol is a flavoring that is briefly allowed in GB 2760-1996. It is mainly made use of to prepare peach, apricot, plum, watermelon, plum, strawberry, walnut, hazel and also other nut flavors.
  4. 3-Phenyl-1-Propanol appropriates for cholecystitis, cholangitis, cholelithiasis, postoperative biliary syndrome and also hypercholesterolemia.
  5. 3-Phenyl-1-Propanol is utilized as a preservative in cosmetics, and also 3-phenylpropanol has an all-natural scent with antibacterial residential properties against microorganisms as well as mold. It is consequently made use of in mix with piperonal or pepper as a preservative in cosmetics. 3-Phenylpropanol or its ester derivatives are used as fragrance components of blossoms, such as lavender, hyacinth, as well as likewise as a part of lily of the valley because of its balsamic odor feature.

3-Phenyl-1-Propanol Production Method

Prepared by catalytic hydrogenation of ethyl cinnamate. The hydrogenation reaction is carried out in an autoclave using a chromium-copper-barium catalyst at a temperature of 200°C and a hydrogen pressure of about 20MPa. After hydrogenation reaction for 5-9h, the catalyst was filtered off by cooling, and the filtrate was extracted with ether. After the ether is recovered from the extract, it is distilled under reduced pressure, and the fraction at 110-112°C (1.06kPa) is collected, which is the finished product, with a yield of about 85%. Another preparation method is to obtain 3-phenylpropanol chloride magnesium salt through Grignard reaction between benzyl chloride and ethylene oxide, and then hydrolyze with sulfuric acid to obtain 3-phenylpropanol. The yield of this method is about 65-70%.

Ecological Information for 3-Phenyl-1-Propanol

The production and usage 3-Phenyl-1-Propanol in the synthesis of flavors and also scent substances, as a taste agent in food and as a chemical in cosmetics may bring about its release into the environment with various waste streams. Utilizing it as an aroma may have a straight impact on the atmosphere. 3-Phenylpropanol takes place usually in materials and also balsams in absolutely complimentary in addition to esterified kind, along with has actually been found in countless fruits and also berries. 3-Phenylpropanol has been identified as a component of cigarette smoke. If released to air, the supposed vapor pressure of 0.0234 mmHg at 25 ° C suggests that 3-phenylpropanol will only be present in the setting as a vapor. Vapor-phase 3-phenylpropanol will break down complimentary radicals in the atmosphere by responding with photochemically produced hydroxyl groups; the half-life of this reaction in air is estimated to be 1.4 days. 3-Phenylpropanol does not include a chromophore that absorbs at > 290 nm, so straight photolysis by sunlight is not anticipated. If released into soil, 3-phenylpropanol is anticipated to be incredibly mobile based upon an approximated Koc of 71. Volatilization from damp dirt surfaces is not expected to be a considerable fate process based on Henry’s regulations constants of less than 5.6X10-8 automated teller machine. cubic meter/mole. There is an evident odor although the vapor anxiety is decreased in the ambience at usual temperature degree and stress; for that reason, 3-Phenyl-1-Propanol could volatilize from completely dry dirt. Making use of the Zahn-Wellens examination, 100% biodegradation was achieved within 4 days, showing that biodegradation is an important environmental fate treatment for dirt as well as water. If launched right into water, 3-phenylpropanol is not expected to adsorb to put on hold solids as well as likewise debris based upon the estimated Koc. Volatilization from the water surface area is not prepared for to be a substantial destiny process based upon the Henry’s regulation constant for this compound. An estimated BCF of 4.5 shows a lowered bioconcentration capability in water bacteria. Hydrolysis is not anticipated to be an important eco-friendly destiny procedure because the substance does not have practical groups that hydrolyze under ambient problems. Occupational direct exposure to 3-Phenyl-1-Propanol might occur from inhalation as well as likewise dermal straight exposure to this compound in workplace where 3-Phenylpropanol is developed or used. Surveillance in addition to use info suggest that the basic populace may be subjected to 3-Phenyl-1- Propanol.

Reconstruction of 3-Phenyl-1-Propanol Metabolic Pathway in Escherichia coli

The biosynthetic pathway of 3-phenylpropanol was redesigned by reverse biosynthesis evaluation approach, integrated with the optimization strategy of metabolic engineering, the effective afresh synthesis of 3-Phenyl-1-Propanol in Escherichia coli was recognized.

In this research study, RetroPath 2.0 was made use of to carry out on-line reverse biosynthesis analysis, and also a path was developed to militarize the synthesis of 3-phenylpropanol from L-phenylalanine, that included phenylalanine ammonia-lyase PAL, enoate reductase ER, carboxyl Acid reductase vehicle and also its turning on protein PPTase, and endogenous aldehyde and ketone reductase AKR or alcohol dehydrogenase ADH. The optimum recombination path including AtPAL2, CaER, SruCAR and also EcPPTase was established by contrasting 5, 3 and also 5 different sources of automobile, PPTase and friend, and also the introduction of CaER in the pathway made the C=C dual bond bring back node The rate limitation of is launched, which can militarize the synthesis of 365.59 mg/L 3-Phenyl-1-Propanol from L-phenylalanine. Change the framework of L-phenylalanine synthesis, knock out the genetics that can increase the supply of precursor PEP as well as release the negative guideline, and construct 6 framework pressures with various knockout combinations, and introduce the 3-Phenyl-1-Propanol recombination pathway Among the checked framework, the ptsG, pykA and pykF three-way knockout framework had the very best compatibility with the recombinant pathway, as well as can manufacture 473.75 mg/L 3-phenylpropanol from glucose. After maximizing the expression strength of path genetics as well as fermentation conditions, Escherichia coli can manufacture 847.79 mg/L 3-phenylpropanol utilizing glucose-glycerol blended carbon source.

This research study developed the synthesis path of 3-phenylpropanol through reverse biosynthesis evaluation, integrated with metabolic engineering, achieved the greatest return of 3-phenylpropanol manufactured by microbes, as well as additionally created as well as engineered pathways for microbial synthesis of other high value-added products Retrofit gives a recommendation.

About Products:
If you need 3-Phenyl-1-Propanol as a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced 3-Phenyl-1-Propanol manufacturer and supplier, ZSpharmac will provide 3-Phenyl-1-Propanol raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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