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2-Methylbutanoic Acid CAS 116-53-0

Molecular Formula: C5H10O2

Formula Weight: 102.13

ZSpharmac: 2-Methylbutanoic Acid Supplier

Product Name: 2-Methylbutanoic Acid
CAS No: 116-53-0
Purity: 99%

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Basic Info

Product Name:2-Methylbutanoic Acid
Other Names:2-Methyl Butyric Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless to Pale Yellow Liquid
EINECS No.:204-145-2
Storage:Sealed in dry,Room Temperature
Provide:2-Methylbutanoic Acid MSDS;
2-Methylbutanoic Acid COA

What is 2-Methylbutanoic Acid?

2-Methylbutyric acid is methylbutyric acid containing a butyric acid core with a 2-methyl substituent. Generated from the amino acid leucine throughout microbial nutrient poor nutrition. It has the influence of microbial metabolites in addition to human metabolites. It is the conjugate acid of 2-methylbutyric acid.

2-Methylbutanoic Acid Property

Melting point 

-70 °C

Boiling point 

176-177 °C (lit.)


0.936 g/mL at 25 °C (lit.)

vapor pressure 

0.5 mm Hg ( 20 °C)

refractive index 

n20/D 1.405(lit.)


165 °F

storage temp. 

Sealed in dry,Room Temperature






4.8(at 25℃)


Clear colorless to pale yellow


at 10.00 % in propylene glycol. pungent acid roquefort cheese

Odor Type


explosive limit


Water Solubility 

45 g/L (20 ºC)


2-Methylbutanoic Acid Uses

  1. 2-Methylbutyric acid is a food flavor that is allowed to be used in GB 2760– 1996. Utilized in the preparation of cheese, lotion, delicious chocolate and other flavors.
  2. 2-Methylbutyric acid is made use of to prepare food, tobacco and also day-to-day chemical flavors.
  3. 2-Methylbutyric acid is an intermediate in the manufacturing of esters utilized in lubricants, plasticizers, fragrances and also fragrances.

2-Application of Methylbutyric acid

2-Methylbutyric acid has a cheese preference as well as typically exists in apples, strawberries, peppers and additionally different other veggies and fruits. It is an artificial additive authorized for usage in my country and several nations on the planet. It is coded S0298 in the nationwide typical GB2760 as well as likewise FEMA number 2695.

Consisting of 2-methylbutyric acid to the feed can market the devastation of carbs and likewise the development of rumen fiber-degrading germs, which helps to soak up fiber in the rumen in addition to remain free from feed waste. The remarkable biosafety in addition to high antifungal task of 2-methylbutyric acid make it have wonderful prospective for even more research and development.

2-methylalkanoic acid with high optical pureness can in addition be utilized as an important made intermediate for the synthesis of different optically pure materials such as natural aromas.For that reason their split has really happy prevalent passion.

Additionally, using 2-methylbutyrate as a biomarker for detecting and/or evaluating a frame of mind problem, a mindset trouble state and/or a renovation in the resulting mental reaction in a topic.

2-Methylbutyric Acid Preparation

Chinese invention application patents CN200310106387.0 and CN97104420.1 disclose the preparation method of 2-methylbutyric acid, which mainly uses food or other natural plants as raw materials, and the by-product fusel alcohol produced after fermentation is subjected to rectification and separation to obtain 2-methylbutyric acid. Methyl butanol is oxidized to 2-methyl butyric acid with 2-methyl butanol as the raw material, and the GC content of 2-methyl butyric acid is about 98% after rectification.

Shi Quan et al. used natural 2-methylbutanol as the starting material to obtain active 2-methylbutyric acid through hydrogen peroxide oxidation, and the optical rotation at 20°C was +18.0°. 

Huang Yongxue et al. used 2-ethylacrolein as a raw material to synthesize 2-methylbutyric acid through continuous reduction and oxidation two-step reaction. The process provided was scaled up to produce 2-methylbutyric acid. , GC≥99.5%. The steps and process conditions are as follows:

The first step: put 2-ethylacrolein and acetone solvent into the reactor, stir well, put 5% palladium carbon or 10% palladium carbon, after nitrogen replacement, feed hydrogen to 1 atmosphere, and control the temperature at 20-60 After the reaction, the solid catalyst was removed by filtration to obtain an intermediate solution.

Step 2: Add 1-5mol% sodium tungstate to the above intermediate solution, and slowly add 25-28% hydrogen peroxide solution dropwise at a temperature of 10-50°C. After the addition, keep warm until the raw material disappears as detected by TLC. The catalyst is filtered and recovered for reuse, the filtrate is distilled to obtain the crude product, and the pure product is obtained after rectification, the content is ≥99.5%, and the two-step yield is 88-93%.

About Products:
If you need 2-Methylbutyric Acid as a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced 2-Methylbutyric Acid manufacturer and supplier, ZSpharmac will provide 2-Methylbutyric Acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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