Zhishang Chemical

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Zhishang Chemical

2-Methyl Butyric Acid CAS 116-53-0

Molecular Formula: C5H10O2

Formula Weight: 102.13

ZSpharmac: 2-Methyl Butyric Acid Supplier

Product Name: 2-Methyl Butyric Acid
CAS No: 116-53-0
Purity: 99%

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Basic Info

Product Name:2-Methyl Butyric Acid
Other Names:2-Methylbutyric Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless to Pale Yellow Liquid
EINECS No.:204-145-2
Storage:Sealed in Dry,Room Temperature
Provide:2-Methyl Butyric Acid MSDS;
2-Methyl Butyric Acid COA

What is 2-Methyl Butyric Acid?

2-Methyl Butyric Acid is methylbutyric acid comprising a butyric acid core with a 2-methyl substituent. Created from the amino acid leucine during microbial nutrient malnourishment. It has functions as a bacterial metabolite and a human metabolite. It is the conjugate acid of 2-Methyl Butyric Acid.

2-Methyl Butyric Acid Property

Melting point 

-70 °C

Boiling point 

176-177 °C (lit.)


0.936 g/mL at 25 °C (lit.)

vapor pressure 

0.5 mm Hg ( 20 °C)

refractive index 

n20/D 1.405(lit.)


165 °F

storage temp. 

Sealed in dry,Room Temperature






4.8(at 25℃)


Clear colorless to pale yellow

explosive limit


Water Solubility 

45 g/L (20 ºC)



2-Methyl Butyric Acid Uses

  1. 2-Methyl Butyric Acid is a food flavor that is enabled to be used in GB 2760– 1996. Made use of in the preparation of cheese, lotion, chocolate and also other flavors.
  2. 2-Methyl Butyric Acid is utilized to prepare food, tobacco as well as day-to-day chemical tastes.
  3. 2-Methyl Butyric Acid is an intermediate in the production of esters utilized in lubricants, plasticizers, perfumes as well as fragrances.

2-Methyl Butyric Acid for Regulation of Gut Microbiota

It is popular that taking in moderate amounts of fruits and vegetables can enhance physical health and wellness and physical function. A healthy and balanced diet regimen, including intake of vegetables and fruits, can alter the gut microbiota. This research study intended to demonstrate the efficiency of created fruit and vegetable supplements (FVS) in regulating antioxidant capability and also intestine microbiota make-up. We hired 30 healthy volunteer topics, matched for age, sex, BMI and cigarette smoking practices, and also randomized them into FVS and also placebo (PLA) teams. Amongst product vitamins, folic acid levels were considerably greater in the FVS group than in the PLA group (p = 0.001), while vitamin B2 degrees were considerably higher in the PLA team than in the FVS team (p = 0.028). Antioxidant capacity measured making use of the oxygen radical absorbance capability (ORAC) method was likewise a little greater in the FVS group than in the PLA group, yet did not get to statistical significance. Nutritional intake examined by 24-h recall did disappoint any kind of significant change after supplementation in either group. Digestive tract microbiome composition gauged by 16S rDNA sequencing showed no distinction in alpha and beta variety, whereas LEfse evaluation revealed adjustments in microbiota after therapy, with lowered wealth of Ruminococcus in the Lachnospiraceae category (p = 0.009), along with those from Erysipelotrichaceae The unclassified category (UC36, p=0.003) of the FVS team compared with the PLA team (verified by SIAMCAT analysis, AUC = 74.1%). The genus Faecalibacterium and also unidentified genera and also families from the order Lactobacillus (UC31) were likewise enhanced in the FVS group compared to the PLA group (p = 0.0474, p = 0.0352, specifically). SCFA measured by gas chromatography-mass spectrometry disclosed elevated levels of 2-methylbutyrate in the FVS group compared to the PLA team (p = 0.0385). Finally, Spearman relationship evaluation showed that in the FVS group, the Faecalibacter category was favorably associated with 2-Methyl Butyric Acid (p = 0.040). In the PLA group, none of the considerable germs correlated with SCFA or product biomarkers. Network analysis validated a favorable connection between the Faecalibacterium genus and also 2-Methyl Butyric Acid. We can wrap up that FVS in healthy individuals changes intestine microbiota composition and metabolites, which may add to minimized pro-inflammatory responses as well as antioxidant ability.

About That Product:
If you need 2-Methyl Butyric Acid as a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced 2-Methyl Butyric Acid manufacturer and supplier, ZSpharmac will provide 2-Methyl Butyric Acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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