Zhishang Chemical

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Zhishang Chemical

2-Butene-1,4-Diol CAS 110-64-5

Molecular Formula: C4H8O2

Formula Weight: 88.11

ZSpharmac: 2-Butene-1,4-Diol Supplier

Product Name: 2-Butene-1,4-Diol
CAS No: 110-64-5
Purity: 99%

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Basic Info

Product Name:2-Butene-1,4-Diol
Other Names:1,4-Butenediol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:yellow Powder
EINECS No.:203-787-0
Provide:2-Butene-1,4-Diol MSDS;
2-Butene-1,4-Diol COA

What is 2-Butene-1,4-Diol?

1,4-Butenediol, English name is 2-Butene-1,4-diol, it is a colorless liquid at normal temperature and pressure, and is easily soluble in water and most organic solvents. 2-Butene-1,4-Diol is a polar molecule in which two hydroxyl functional groups can form hydrogen bonding interactions with water molecules. The compound has certain applications in the pharmaceutical and cosmetic industries, and the compound can be used as an intermediate in the synthesis of insecticides and vitamin B6 in pesticides.

2-Butene-1,4-Diol Property

Melting point 4-10 °C(lit.)
Boiling point 235 °C(lit.)
density 1.07 g/mL at 25 °C(lit.)
refractive index n20/D 1.479
Fp >230 °F
color yellow


2-Butene-1,4-Diol Uses

  1. 2-Butene-1,4-diol is used as a plasticizer for alkyd resin, a crosslinking representative for synthetic material, a fungicide, and so on. It can also be utilized to make 1,4-butanediol, etc 2-Butene-1,4-diol is a chemical as well as pharmaceutical intermediate, which is made use of in the synthesis of endosulfan, an intermediate of organochlorine insecticide endosulfan.
  2. 2-Butene-1,4-diol is primarily utilized as an intermediate in the preparation of chemicals, agricultural chemicals as well as vitamin B6, as well as a percentage is used in polymer production.
  3. 2-Butene-1,4-diol can likewise be used to make nylon, medication, 1,4-butanediol, and so on.

2-Butene-1,4-Diol Applications

2-Butene-1,4-Diol can be used as an intermediate in organic synthesis and medicinal chemistry, and is mostly used in the synthesis of fine chemicals and bioactive molecules. For example, 1,4-butenediol is an important raw material in the synthesis of vitamin B6 and has important application value. Vitamin B6, also known as pyridoxine, is an important water-soluble vitamin that plays an important role in the growth and development of the human body, the nervous system, and the immune system. Its chemical structure contains benzene rings and pyrazine rings, while 2- Butene-1,4-Diol is an important intermediate in the synthesis of vitamin B6. Application of 2-Butene-1,4-Diol


Figure 1 Application of 1,4-butenediol

Sodium hydride (3.27 g, 60% in oil, 81.2 mmol) and tetrahydrofuran were added to a dry reaction flask, and then 1,4-butenediol (3.0 g, 3.4 mmol) was slowly added to the reaction mixture. When the reaction will obviously evolve gas, be careful to balance the pressure change in the reaction. The resulting reaction mixture was stirred at room temperature for several hours, then a solution of methyl iodide (10.6 mL, 170 mmol) in tetrahydrofuran (60 mL) was added, the mixture was stirred at 0°C for 10 min, then the cooling bath was removed and placed in Stir at 25°C for 24 h. After the reaction, the reaction mixture was slowly poured into 60 mL of brine, and then extracted with ether (3 × 50 mL). The combined organic layers were dried with anhydrous magnesium sulfate, the desiccant was removed by filtration and the obtained filtrate was concentrated to obtain a colorless oil, and the pure target product was obtained by distillation under reduced pressure.

2-Butene-1,4-Diol Production Method

Its preparation method is to obtain 1,4-butenediol by catalytic hydrogenation of 2-Butene-1,4-Diol.
Mix 40% butynediol aqueous solution with 50% Raney nickel, add inhibitor ammonia water, and pass in hydrogen gas at a pressure of about 0.5kPa until the theoretical hydrogen absorption capacity is reached. Filtrate, distill the filtrate under reduced pressure, and collect fractions at 110-114°C/8kPa to obtain 2-Butene-1,4-Diol.

About Products:
If you need 2-Butene-1,4-Diol this cosmetic raw material, please contact our service personnel directly, we will provide you with high-quality products at the best price.
As an experienced 2-Butene-1,4-Diol manufacturer and supplier, ZSpharmac will provide 2-Butene-1,4-Diol raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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