1,4-Butenediol, English name is 2-Butene-1,4-diol, it is a colorless liquid at normal temperature and pressure, and is easily soluble in water and most organic solvents. 2-Butene-1,4-Diol is a polar molecule in which two hydroxyl functional groups can form hydrogen bonding interactions with water molecules. The compound has certain applications in the pharmaceutical and cosmetic industries, and the compound can be used as an intermediate in the synthesis of insecticides and vitamin B6 in pesticides.
1.07 g/mL at 25 °C(lit.)
2-Butene-1,4-diol is used as a plasticizer for alkyd resin, a crosslinking representative for synthetic material, a fungicide, and so on. It can also be utilized to make 1,4-butanediol, etc 2-Butene-1,4-diol is a chemical as well as pharmaceutical intermediate, which is made use of in the synthesis of endosulfan, an intermediate of organochlorine insecticide endosulfan.
2-Butene-1,4-diol is primarily utilized as an intermediate in the preparation of chemicals, agricultural chemicals as well as vitamin B6, as well as a percentage is used in polymer production.
2-Butene-1,4-diol can likewise be used to make nylon, medication, 1,4-butanediol, and so on.
2-Butene-1,4-Diol can be used as an intermediate in organic synthesis and medicinal chemistry, and is mostly used in the synthesis of fine chemicals and bioactive molecules. For example, 1,4-butenediol is an important raw material in the synthesis of vitamin B6 and has important application value. Vitamin B6, also known as pyridoxine, is an important water-soluble vitamin that plays an important role in the growth and development of the human body, the nervous system, and the immune system. Its chemical structure contains benzene rings and pyrazine rings, while 2- Butene-1,4-Diol is an important intermediate in the synthesis of vitamin B6. Application of 2-Butene-1,4-Diol
Figure 1 Application of 1,4-butenediol
Sodium hydride (3.27 g, 60% in oil, 81.2 mmol) and tetrahydrofuran were added to a dry reaction flask, and then 1,4-butenediol (3.0 g, 3.4 mmol) was slowly added to the reaction mixture. When the reaction will obviously evolve gas, be careful to balance the pressure change in the reaction. The resulting reaction mixture was stirred at room temperature for several hours, then a solution of methyl iodide (10.6 mL, 170 mmol) in tetrahydrofuran (60 mL) was added, the mixture was stirred at 0°C for 10 min, then the cooling bath was removed and placed in Stir at 25°C for 24 h. After the reaction, the reaction mixture was slowly poured into 60 mL of brine, and then extracted with ether (3 × 50 mL). The combined organic layers were dried with anhydrous magnesium sulfate, the desiccant was removed by filtration and the obtained filtrate was concentrated to obtain a colorless oil, and the pure target product was obtained by distillation under reduced pressure.
2-Butene-1,4-Diol Production Method
Its preparation method is to obtain 1,4-butenediol by catalytic hydrogenation of 2-Butene-1,4-Diol. Mix 40% butynediol aqueous solution with 50% Raney nickel, add inhibitor ammonia water, and pass in hydrogen gas at a pressure of about 0.5kPa until the theoretical hydrogen absorption capacity is reached. Filtrate, distill the filtrate under reduced pressure, and collect fractions at 110-114°C/8kPa to obtain 2-Butene-1,4-Diol.
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ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .
The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .
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Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.
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