Zhishang Chemical

Welcome to Zhishang Chemical      +86-176 5311 3209     Simon@sdzschem.com

Zhishang Chemical

1,3-Propanediol CAS 504-63-2

Molecular Formula: C3H8O2

Formula Weight: 76.09

ZSpharmac: 1,3-Propanediol Supplement

Product Name: 1,3-Propanediol
CAS No: 504-63-2
Purity: 99%

Navigation Bar

Basic Info

Product Name:1,3-Propanediol
Other Names:1,3-Dihydroxypropane
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Oily Liquid
EINECS No.:207-997-3
Storage:Store Below +30°C.
Provide:1,3-Propanediol MSDS;
1,3-Propanediol COA

What is 1,3-Propanediol?

1,3-Propanediol is a new type of chemical raw material with great potential. It is widely used in the manufacture of polyester fibers, polyurethane, hot melt adhesives, powder coatings, antifreeze agents, packaging materials and organic synthesis intermediates. Among them, the production of high-performance polyester-polytrimethylene terephthalate (PTT) is the main purpose at present. 1,3-Propanediol can be produced by chemical route and biological route. Among them, 1,3-propanediol is produced by biotechnology, which is characterized by its green chemistry, mild reaction conditions, easy operation, less by-products, and less environmental pollution. Renewable resources and other characteristics have become one of the hotspots of biochemical research in the new century.

1,3-Propanediol Properties:

Melting point 

-27 °C (lit.)

Boiling point 

214 °C/760 mmHg (lit.)


1.053 g/mL at 25 °C (lit.)

vapor pressure 

0.8 mm Hg ( 20 °C)

refractive index 

n20/D 1.440(lit.)


>230 °F

storage temp. 

Store below +30°C.


H2O: soluble




Oily Liquid




4.5-7.0 (100g/l, H2O, 20℃)

explosive limit


Water Solubility 

100 g/L


1,3-Propanediol Uses

  1. 1,3-Propanediol is used in organic synthesis, synthesis of various drugs and new antioxidants.
  2. 1,3-Propanediol is used as an antifreeze. solvent. Organic Synthesis. Standard for Gas Chromatography.
  3. 1,3-Propanediol can be utilized in the synthesis of different drugs, new polyester PTT, pharmaceutical intermediates as well as new anti-oxidants.

Application of 1,3-Propanediol

1,3-Propanediol-(1,3-Propanediol, described as 1,3-PD) is a vital solvent and also chemical basic material. Presently, the main use is for the synthesis of polyester, polyether, polyurethane, etc. Polyester PTT (polytrimethylene terephthalate) manufactured from 1,3-propanediol and terephthalic acid has a vast array of application leads in the fields of synthetic fiber materials, polyester films, design plastics and textile and clothing materials. 1,3- Propylene glycol has been proposed for usage in individual treatment solutions as well as cosmetics, yet is not known to be typically utilized in the food industry. 1,3-Propanediol is a polar substance that can be prepared from corn sugar. 1,3-Propanediol can be utilized in food as well as drink items to enhance anger features contrasted to food or drink items that are otherwise identical except that they do not have 1,3-propanediol. It has been remarkably as well as unexpectedly uncovered that the inclusion of 1,3-propanediol in food and also drink items in really percentages can reduce the bitter preference of specific components in food and beverage products. In one aspect, 1,3-propanediol is effective in minimizing bitterness associated with high intensity sugar in food and beverage products. In a particularly preferred facet, the high strength sweetener includes several steviol glycosides. In an additional aspect, 1,3-propanediol is effective in lowering resentment connected with salt alternatives such as potassium chloride in food and also beverage items.

In general, the 1,3-propanediol is included in the food or drink item in an amount such that the 1,3-propanediol itself does not give taste to the food or beverage product as well as its addition in the item can not be perceived by the taste. As an example, 1,3-propanediol is typically taken into consideration to be included below the sensory noticeable flavor threshold for the average consumer. To put it simply, the relative product without 1,3-propanediol had no significant difference in preference from the product with 1,3-propanediol. If desired, the amount of 1,3-propanediol can also be determined by dilution in water to make certain that the 1,3-propanediol does not supply flavor to the food or drink.

1,3-Propanediol Production Technology and Development Trend

Presently, there are 3 type of industrial 1,3-PDO production approaches: acrolein hydration technique, ethylene oxide hydroformylation approach and also organic fermentation method Amongst them, the acrolein hydration technique was constructed by Degussa in 1996 with 50,000 heaps/ Annual plant; ethylene oxide hydroformylation method was built by Covering in 1999 with a 72,000-ton/ year industrial plant; biological fermentation approach was built by DuPont in 2006 with a 45,000-ton/ year plant, as well as various other developing Procedures include formaldehyde-acetaldehyde condensation process, ethylene synthesis procedure by Pris reaction, glycerol chemical procedure and also 3-hydroxypropionaldehyde (3-HPA) one-step synthesis procedure. Because the biological fermentation approach has the advantages of light reaction problems, simple operation, much less byproducts, as well as far better option. The benefits of great selectivity, low energy intake, less equipment financial investment, and also environmental kindness have actually ended up being a hot spot in today’s development.
2.1 Acrolein hydration approach.

The process created by Degussa at first utilized an unique ion exchange material driver, as well as included a chelating practical team containing methyleneiminodiacetic acid, as well as the reaction was carried out at 60 ° C. The conversion price of acrolein was 82%, as well as 3-hydroxypropionaldehyde (HPA) selectivity was 80%. After that, 1,3-PDO was gotten by two-stage hydrogenation. When Raney nickel was used as the stimulant, the carbonyl content was minimized from 1000 ppm to below 100 ppm. Degussa transferred the innovation to DuPont in 1998.
2.2 Hydroformylation of ethylene oxide

The procedure created by Shell operates in two actions, first by hydroformylation of ethylene oxide with syngas to HPA, complied with by hydrogenation to 1,3-PDO. The trick to the Covering procedure is using cobalt carbonyl catalysts in the hydroformylation process, and also using numerous ligands (such as diphosphine, trihydrophosphine, arsine, etc) and ingredients (tetrabutylphosphorus acetate, butylpentane, and so on) pyridine, and so on), based on ethylene oxide, the yield of 1,3-PDO can reach 85% to 90%, and also the product pureness can get to 99.6% (mass ratio).
2.3 Biological fermentation approach

The method consists of the option of raw materials, fermentation innovation, removal of bacteria and also healthy proteins, desalination and also rectification.
Along with the target product, the 1,3-PDO fermentation method likewise consists of microbial strains, healthy proteins, nucleic acids, polysaccharides, not natural salts, organic acid salts, glycerol, 2,3-butanediol, water, etc, which is a really intricate procedure. Furthermore, 1,3-PDO is extremely polar, as well as the concentration in the fermentation broth is reduced (concerning 50-110 g/L in one stage), so it is tough to different as well as recover 1,3-PDO from water down service, which likewise restricts organic Approach 1,3 – The essential to PDO manufacturing. In order to address the many problems existing in the whole separation process, it is essential to more optimize the purification process, especially to develop a cost-effective as well as reliable splitting up method, while improving the return and high quality of 1,3-PDO, streamlining the process route, lowering power usage, recycling High value-added by-products in fermentation broth.

Along with organic synthesis of 1,3-PDO, chemical synthesis of 1,3-PDO from glycerol is also worthy of interest. As an example, the research study group of Tohoku University in Japan as well as Daicel have created a procedure for creating 1,3-PFO from glycerol produced by biodiesel. The procedure uses powdered Ir-ReOX/SiO2 stimulant distributed in the reaction remedy, and also the selectivity of 1,3-PDO reaches 60%. The research team likewise confirmed the reaction mechanism for the development of 1,3-PDO using a 2,3-= hydroxypropanol intermediate. The study team additionally enabled the reaction to be carried out in a fixed-bed activator by utilizing an optimized spherical catalyst sustained on silica gel. Continuous operation at laboratory range for more than 300 hrs reveals that the catalyst still maintains high task and also selectivity. Therefore, it can be thought about that the scale-up examination of the industrial path can be carried out, and also the reaction spin-off propanol can likewise be marketed as a solvent. 3 Residential as well as international market supply as well as need and also forecast

In recent years, there have been couple of records of brand-new 1,3-PDO manufacturing plants abroad. The existing manufacturing ability is estimated to be 265,000 tons/year, the largest of which is Shell’s ethylene oxide hydroformylation unit in Geismar, Louisiana, U.S.A., with a production ability of 136,000 tons/year; Degussa’s Weisser, Germany In the Wesseling location, there are 2 sets of acrolein hydration units with a manufacturing capability of 18,000 tons/year as well as 50,000 tons/year respectively. DuPont has a 18,000-ton/ year acrolein hydration device in Germany and also a collection of acrolein hydration units in Tennessee, U.S.A.. The bio-fermentation unit of the firm has a production capability of regarding 60,000 tons/year after expanding its capacity by 30% in 2011. Shell has actually predicted that the need for PTT, the major downstream item of 1,3-PDO, is expected to reach 1 million bunches in the following few years, as well as the needed 1,3-PDO will reach 360,000 lots. Clearly, the existing manufacturing ability can not satisfy the marketplace need.

Currently, my country’s yearly intake of PTT has actually surpassed 30,000 lots, representing about 10% of the world’s total consumption. 90% of PTT intake is straight made use of for spinning as fibers, as well as the continuing to be 10% is utilized for design plastics, of which about two-thirds of fibers are made use of for clothing as well as one-third for carpets. In the following couple of years, the potential market need for PTT in China will certainly be 50,000 to 100,000 tons.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get 1,3-Propanediol Quotation