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1,3-Dihydroxyacetone CAS 96-26-4

Molecular Formula: C3H6O3

Formula Weight: 90.08

ZSpharmac: 1,3-Dihydroxyacetone Supplier

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Product Name: 1,3-Dihydroxyacetone
CAS No: 96-26-4
Purity: 99%

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Basic Info

Product Name:1,3-Dihydroxyacetone
Other Names:Dihydroxyacetone
CAS:96-26-4
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:202-494-5
Storage:Store at +2°C to +8°C.
Provide:1,3-Dihydroxyacetone MSDS;
1,3-Dihydroxyacetone COA

What is 1,3-Dihydroxyacetone?

1,3-Dihydroxyacetone, a sort of triose, is a white deliquescent crystalline powder with an awesome wonderful preference as well as a particular odor. It is the most basic ketose. No chiral facility, so no optical task. Generally exists as a dimer, as well as the dimer can be gradually dissolved in a mixture of 1 part of water and 15 parts of ethanol. Freshly prepared 1,3-Dihydroxyacetone can be quickly converted into monomer in solution, and the monomer is quickly soluble in water, ethanol, ether and also acetone. It can be removed from plants such as sugar beetroot and also sugarcane, and also can additionally be obtained by mild oxidation of glycerol (such as hydrogen peroxide as oxidant, catalyzed by ferrous salt), and the response will certainly additionally create glyceraldehyde. It is generally used as an ingredient in sun-free tanning items such as sun block.

1,3-Dihydroxyacetone, whose chemical name is 1,3-dihydroxy-2-propanone, is a common ingredient in cosmetics for skin moisturizing, self-tanning and hair coloring. Currently, DHA is not within the scope of EU Cosmetic Regulation (EC) No.1223/2009.
In 2008, the EU Scientific Committee on Consumer Safety (SCCS) received a set of application materials from enterprises to support the safety of DHA as a cosmetic ingredient. Its research data show that it is safe to use DHA with a concentration of no more than 10% as a self-tanning agent in cosmetics. In addition, it is safe to use DHA with a concentration of no more than 14% as a self-tanning agent in spray cosmetics.
In May 2019, SCCS received another application to evaluate the safety of DHA with a concentration not exceeding 6.25% when used as a hair dye in resident (non-oxidative) hair dye cosmetics.
According to the safety evaluation data provided by the company on toxicokinetics, skin irritation and sensitization, acute toxicity, reproductive toxicity, mutagenicity, and carcinogenicity, the EU Scientific Committee on Consumer Safety (SCCS) came to the following conclusions after evaluation: It is safe to use more than 6.25% DHA as a hair dye ingredient in resident (non-oxidative) hair dye cosmetics. Leave-in (non-oxidative) hair dye cosmetics with a concentration of DHA not exceeding 6.25% as hair dye ingredients are considered safe when used together with self-tanning lotions or face creams with a concentration not exceeding 10% DHA.

1,3-Dihydroxyacetone Property

Melting point 

75-80 °C

Boiling point 

107.25°C (rough estimate)

density 

1.1385 (rough estimate)

vapor pressure 

0.002-0.33Pa at 20-50℃

refractive index 

1.4540 (estimate)

storage temp. 

Store at +2°C to +8°C.

pka

12.45±0.10(Predicted)

form 

powder

color 

White

Water Solubility 

>250 g/L (20 ºC)

 

 

1,3-Dihydroxyacetone Uses

  1. 1,3-Dihydroxyacetone is made use of in pharmaceutical intermediates, chemical raw materials and also preservative. 1,3-Dihydroxyacetone, as a pharmaceutical intermediate, can manufacture some drugs for treating heart diseases; UV radiation.
  2. 1,3-Dihydroxyacetone
    1. Made use of in the cosmetics industry Dihydroxyacetone is mostly utilized as a basic material for cosmetic solutions, particularly as a sunscreen with special impacts, which can stop too much dissipation of skin wetness, and also play the duty of hydrating, sunscreen as well as anti-ultraviolet radiation. In addition, the ketone functional group in DHA can respond with the amino acid and also amino team of skin keratin to develop a brown polymer, which makes people’s skin create a fabricated brown color, so it can also be used as a sun-tanned skin simulation agent to get a skin that looks comparable to the sun. Long term direct exposure to the sun leads to the very same brown or tan skin that makes it look beautiful.
    2. Improve the lean meat rate of pigs. Dihydroxyacetone is an intermediate product of sugar metabolic process and also plays an essential function in the process of sugar metabolic process.

1,3-Dihydroxyacetone Ecological Information

The manufacturing and use of 1,3-Dihydroxyacetone as a chemical intermediate as well as synthetic tanning agent may cause its release right into the setting via numerous waste streams. If released to air, the vapor stress at 25 ° C is 4.35X10-5 mmHg, indicating that dihydroxyacetone will only exist as a vapor in the ambience. Vapor-phase 1,3-Dihydroxyacetone will break down complimentary radicals in the ambience by responding with photochemically created hydroxyl teams; the half-life of this response in air is estimated to be 2 days. Dihydroxyacetone does not include chromophores that take in at wavelengths > 290 nm as well as is as a result anticipated to be less susceptible to photolysis by straight sunlight. If released into dirt, 1,3-Dihydroxyacetone is anticipated to be extremely mobile based upon an estimated Koc of 1. Volatilization from damp soil surfaces is not expected to be a significant fate procedure based on an estimated Henry’s legislation constant of 5.5X10-12 atm-cu m/mol. Depending on its vapor pressure, 1,3-Dihydroxyacetone might not volatilize from completely dry dirt surface areas. No biodegradation information in soil or water. If released into water, dihydroxyacetone is not expected to adsorb to suspended solids and debris based on the approximated Koc. Volatilization from the surface area is not anticipated to be an important fate procedure based on the estimated Henry’s law constant for this compound. An estimated BCF of 9 suggests a reduced bioconcentration potential in water microorganisms. Hydrolysis is not expected to be a crucial environmental fate process due to the fact that the substance does not have useful teams that hydrolyze under ambient problems (pH 5 to 9). Work direct exposure to dihydroxyacetone might arise from inhalation and dermal direct exposure to this substance in workplaces where 1,3-Dihydroxyacetone is produced or made use of. Usage data indicate that the basic populace may be revealed to dihydroxyacetone with dermal exposure to customer products containing 1,3-Dihydroxyacetone.

Effect of Pyruvate, 1,3-Dihydroxyacetone

Pyruvate and also 1,3-Dihydroxyacetone are three carbon compounds that create solid metabolic results when injected straight right into the bloodstream or by mouth. When fed persistantly to pets as part of the diet regimen, pyruvate plus 1,3-Dihydroxyacetone minimizes the rate of weight gain and also body fat web content during development. These modifications in development patterns seem the result of boosted thermal heat loss at the cost of lipid storage. Pyruvate-1,3-Dihydroxyacetone supplementation was additionally found to boost insulin sensitivity in insulin-resistant rats, decrease plasma cholesterol levels caused by a high-cholesterol diet regimen, as well as lower high blood pressure and also heart price in obese people. When infused right into rats during long term treadmill runs, pyruvate decreased running time by around 67%. Nonetheless, when taken as an oral supplement over several days, it can enhance cardiovascular endurance. The device of action is unknown, but readily available information suggest that the boosted workout efficiency complying with pyruvate-1,3-Dihydroxyacetone supplements might be the outcome of an enhanced dependence on blood glucose, thus sparing muscle glycogen. To conclude, long-term supplementation with 1,3-Dihydroxyacetone pyruvate might profit the outlook of preventive medicine in addition to specific workout programs.

About Products:
If you need 1,3-Dihydroxyacetone as a cosmetic raw material, please contact our service personnel directly, and we will provide you with high-quality products at the best price.
As an experienced 1,3-Dihydroxyacetone manufacturer and supplier, ZSpharmac will provide 1,3-Dihydroxyacetone raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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