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1,2-Pentanediol CAS 5343-92-0

Molecular Formula: C5H12O2

Formula Weight: 104.15

ZSpharmac: 1,2-Pentanediol Supplier

Product Name: 1,2-Pentanediol
CAS No: 5343-92-0
Purity: 99%

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Basic Info

Product Name:1,2-Pentanediol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless to Light Yellow Liquid
EINECS No.:226-285-3
Storage:Keep in Dark Place,Sealed in Dry,Room Temperature
Provide:1,2-Pentanediol MSDS;
1,2-Pentanediol COA

What is 1,2-Pentanediol?

1,2-Pentanediol is a vital natural intermediate, which is taken advantage of in the synthesis of propiconazole, an unique fungicide for economic plants; it additionally has superb moisturizing domestic or industrial homes and also disinfectant effects, as well as is made use of in skin creams, eye creams, skin therapy water, child care items, Different skin therapy things such as sunscreen are additionally essential resources for the production of polyester fibers, surfactants, medications as well as also different other products.

1,2-Pentanediol is an exceptional humectant with anti-bacterial effect, has synergistic result with conventional chemicals as well as also help to reduce the amount of typical chemicals in the formula. In sunscreen items, it is extra useful to enhance the water resistance of the product as well as also the solubility of some energetic ingredients. 1,2-Pentanediol assists to stabilize the formula in addition to also reduces the moisture of the solution as a result of the addition of polymers.

1,2-Pentanediol Property

Melting point 50.86°C (estimate)
Boiling point 206 °C (lit.)
density 0.971 g/mL at 25 °C (lit.)
vapor pressure 1.5Pa at 20℃
refractive index n20/D 1.439(lit.)
Fp 104 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Liquid
color Clear colorless to light yellow
Water Solubility miscible


1,2-Pentanediol Application

1,2-O-diol is an important chemical raw material, which is generally made use of to produce polyester as well as also surfactant, as well as can also be made use of as a raw material for drugs. Straight-chain 1,2-o-diols, particularly C2-C4 o-diols, are primarily prepared by hydration of epoxides under high temperature and additionally anxiety or alkaline or acidic problems, as well as can in addition be prepared by oxidative hydration of terminal olefins.

1,2-pentanediol (1,2-o-diol of C5) is a vital natural intermediate, it is mostly used for the synthesis of the fungicide propiconazole, along with likewise for the manufacturing of polyester fibers, surfactants, cosmetics, medications crucial raw materials for items. United States Certificate No. 4,605,795 A (1986-08-12) discloses a constant production treatment. In a solvent, n-pentene as well as likewise peroxypropionic acid react to produce 1,2-epoxypentane, which desires that hydrated to get 1,2-pentanediol.

1,2-Pentanediol is a direct diol with unique polar in addition to non-polar ends, which is different from different other diols as well as also has multifunctionality. It is the essential intermediate of propiconazole, a systemic fungicide with high performance, low toxicity as well as long duration; propiconazole has really played an important responsibility in the control of fungal damages in food plants, vegetables, fruits, and so on, and also has an extremely wide application prospect. As an excellent humectant, anti-bacterial representative along with solubilizer, 1,2-pentanediol can properly enhance the water resistance of sun block cosmetics and is typically used in countless everyday care products.

Furthermore, 1,2-pentanediol is additionally an essential raw material for products such as polyester fibers, surfactants and pharmaceuticals. There are 2 major processes for the synthesis of 1,2-pentanediol reported in existing literature: one uses n-valeric acid as a basic material, goes through bromination to obtain α-bromo-n-valeric acid, and also hydrolyzes to get α-hydroxyvaleric acid. Hydrogen decline returns 1,2-pentanediol. The various other uses n-pentene as a raw material in addition to makes use of an oxidant system such as formic acid/hydrogen peroxide or peroxypropionic acid to oxidize n-pentene to pentoxide; hydrolyze it under alkaline conditions to get 1,2-pentanediol. The above-mentioned man-made course of 1,2-pentanediol tackles the petrochemical product C5.

The C5 part created in the petrochemical industry is generally made use of as gas, as well as also the return of 1-pentene or various other deep-processed things that can be taken advantage of as sources after rectification as well as splitting up is extremely reduced, causing high resources expenses for the manufacturing of 1,2-pentanediol. The previous art takes on multi-step response, and likewise there are lots of sort of byproducts, which cause decreased return in addition to thing purity of 1,2-pentanediol as well as high price; backwards production modern innovation is also a necessary reason impacting the development of 1,2-pentanediol. This significantly restricts the commercial manufacturing of 1,2-pentanediol.

Product Properties of 1,2-Pentanediol

1. Broad-spectrum antibacterial activity, can effectively inhibit Gram-negative bacteria, positive bacteria, yeast and mold.
2. As an emollient, pentylene glycol has good skin moisturizing properties, can reduce the loss of water in the skin, make the skin soft and smooth, and improve the moisturizing function of skin care products.
3. Pentylene glycol is a multi-functional ingredient with excellent ability to inhibit microorganisms. Its ingredients are not registered as preservatives. It can be used in cosmetics and fully supports the concept of “zero added preservatives”.
4. Mild and non-irritating, reducing irritation and allergies caused by preservatives. It is also a high-purity liquid emollient with broad-spectrum antibacterial effect. It is classified as emollient, very mild, in line with international regulations, and widely used around the world .
5. Good compatibility, can be added to the oil phase, can improve the water resistance of sunscreen product formula; soluble in water, easily soluble in ethylene glycol, propylene glycol, glycerin and other polyols.

Preparation of 1,2-Pentanediol

Fill 150g of hydrogenation catalyst-alloy catalyst (composed of 60g of copper oxide, 45g of zinc oxide and 45g of aluminum oxide) into the hydrogenation reactor, maintain the temperature in the reactor at 165°C, maintain the hydrogen pressure at 14MPa, and enter the hydrogenation from the lower end Reactor, the 2-hydroxyvaleric acid methyl ester that produces in the above-mentioned reaction enters the hydrogenation reactor from the lower end, the feeding flow rate of 2-hydroxyvaleric acid methyl ester (171g) is controlled at 2ml/min, the product of hydrogenation reaction is from hydrogenation reaction The top of the device flows out, and the effluent is cooled to 60°C by a condenser, and then transferred to a distillation pot at a distillation temperature of 160°C to obtain 121.6g of 1,2-pentanediol. The 1,2-pentanediol prepared above is detected by gas chromatography The content of 1,2-pentanediol was 99.3%, and the molar yield was 90.26%.

About Products:
If you need 1,2-Pentanediol as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced 1,2-Pentanediol manufacturer and supplier, ZSpharmac will provide 1,2-Pentanediol raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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