Zhishang Chemical

Welcome to Zhishang Chemical      +86-176 5311 3209     Simon@sdzschem.com

Zhishang Chemical
Close this search box.

1,2-Hexanediol CAS 6920-22-5

Molecular Formula: C6H14O2

Formula Weight: 118.17

ZSpharmac: 1,2-Hexanediol Supplier

Product Name: 1,2-Hexanediol
CAS No: 6920-22-5
Purity: 99%

Navigation Bar

Basic Info

Product Name:1,2-Hexanediol
Other Names:DL-1,2-Hexanediol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless to Light Yellow Liquid
EINECS No.:230-029-6
Storage:Inert Atmosphere,Room Temperature
Provide:1,2-Hexanediol MSDS;
1,2-Hexanediol COA

What is 1,2-Hexanediol?

1,2-Hexanediol is a crucial chemical basic material, which is mostly utilized in the ink of shade inkjet printers, advanced cosmetics as well as synthetic raw materials in the pharmaceutical sector. Currently, most of the Chinese licenses related to the application of 1,2-hexanediol were applied by business from Japan, the USA, Germany and also various other nations in China before 2011. After 2014, the number of license applications by Chinese companies or individuals raised, but primarily related just to cosmetics.

1,2-Hexanediol Property

Melting point 45°C
alpha [α]D20 -0.3~+0.3゜ (neat)
Boiling point 223-224 °C (lit.)
density 0.951 g/mL at 25 °C (lit.)
vapor pressure 0.576Pa at 25℃
refractive index n20/D 1.442(lit.)
Fp >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Liquid
Specific Gravity0.951
color Clear colorless to light yellow
Water Solubility Miscible with water, lower aliphatic hydrocarbons and fatty acids.


1,2-Hexanediol Application

1. Application in ink
Printers are a device commonly utilized in modern culture, and also 1,2-hexanediol can be utilized as a raw material for inkjet printing inks in printers, as well as its use is becoming an increasing number of extensive. Canon, Seiko Epson, etc include 1,2-hexanediol to the ink to obtain a much more consistent ink with excellent ozone resistance and also gloss.

2. Application in cosmetics
1,2-hexanediol is contributed to day-to-day needs and made use of as a preservative touching the human body. It has the effect of sanitation as well as moisturizing, as well as at the same time does not have an adverse effect on human health and wellness. Many patents or articles discuss that the combination of 1,2-hexanediol and also other compounds with antimicrobial result can play an antimicrobial impact. Procter & Wager added 1,2-hexanediol to deodorants as well as antiperspirants, as well as the resulting deodorants/antiperspirants are much better in deodorant/antiperspirant, and have far better skin feel and transparency, as well as are much more reliable for the skin. moderate.

Aussie of the United States added 1,2-hexanediol to the eyelid scrub option, and also Givaudan Co., Ltd. and Japan Co., Ltd. FANCL additionally included 1,2-hexanediol to skin care structures. Use rather than other antiseptic chemicals. Dow Global Technologies utilizes 1,2-hexanediol as opposed to alcohol to include in the fragrance, initially to decrease skin irritability, and second, due to its exceptional solvent and solubilizing capacity, it decreases using surfactants. A product with high security can be gotten. Chinese cosmetics companies additionally include 1,2-hexanediol to cosmetics, which is decontaminated and disinfectant and less bothersome to the skin, boosting the security of skin care products.

3. Application in the pharmaceutical market
1,2-Hexanediol is generally used as a chemical raw material in the pharmaceutical sector, giving a basis for the growth and utilization of downstream products.

4. Various other applications
1,2-Hexanediol can be used in high-grade layers, top-quality adhesives, adhesives, and so on. It is also an intermediate in organic synthesis, as well as can be used to manufacture downstream products such as 1,2-hexanedioic acid as well as amino alcohols.

Safety of 1,2-Hexanediol

1. About skin irritation
Safety test data based on safety ingredient review (Reference 1: 2012) [Human Trial] 205 participants (42 males, 163 females) applied 15% 1,2-hexanediol in the induction and challenge phases Carbomer Gel 48 hours. Responses were scored after 72 hours, of which 1 in 205 showed irritation, but no subsequent responses were observed in the 4-day repeat-release patch test. · [Human Test] A skin irritation test was conducted on 224 subjects (48 males, 176 females, 19-70 years old) using carbomer gel containing 0.5% 1,2-hexanediol. There was also no skin irritation · [Human Trials] When 56% of the participants used a 10% 1,2-hexanediol aqueous solution, none of the participants caused skin irritation. · [Human test] A gel preparation containing 0.5% 1,2-hexanediol was applied to the back of 101 participants on a 24-hour semi-occlusive patch, which did not cause skin irritation. · [Human Trial] 28 participants were washed twice a week with body wash containing 0.15% 1,2-hexanediol on their backs for 30 days, none of them experienced erythema, edema or dryness . Conclusion The product has no potential skin irritation. Based on test data, little to no skin irritation was generally reported as no skin irritation was generally reported.

2. About eye irritation
Based on Safety Ingredient Review safety test data (Reference 1:2012) A 1% aqueous solution of a mixture of 50% 1,2-hexanediol and 50% octanediol is classified as a severe eye irritant

Based on test data, serious eye irritation has been reported, therefore serious eye irritation has the potential to occur.

3. About skin allergies
According to the safety test data of the Safety Ingredient Review (Reference 1: 2012) [Human Trial] When 56% of the participants used 10% 1,2-hexanediol aqueous solution, none of the participants caused skin sensitization. · [Human Test] 28 participants were washed with body wash containing 0.15% 1,2-hexanediol on their backs twice a week for 30 days. Conclusion The product has no potential to induce skin sensitization · [Animal test] In the mouse skin sensitization test according to OECD429 guidelines, 10, 50, 100% 1,2-hexanediol solutions were evaluated, and the skin sensitization was negative.

Synthesis of 1,2-Hexanediol

H2O2 is an oxidant that has been used more in recent years. By oxidizing organic acids to peroxyacids, the peroxyacids epoxidize the double bonds of olefins, and finally hydrolyze to obtain diols. The reaction mechanism is shown in Figure 2.


The advantage of the H2O2 oxidation method is that H2O2 is cheap and high in quality, and after being reduced, water will be generated, the environmental pollution is small, and it is suitable for industrial production requirements.

About Products:
If you need 1,2-Hexanediol as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced 1,2-Hexanediol manufacturer and supplier, ZSpharmac will provide 1,2-Hexanediol raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get 1,2-Hexanediol Quotation