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1,2-Dimethyl-5-Nitroimidazole CAS 551-92-8

Molecular Formula: C5H7N3O2

Formula Weight: 141.13

Zhishang Chemical: 1,2-Dimethyl-5-nitroimidazole Supplement

Product Name: 1,2-Dimethyl-5-nitroimidazole
CAS No: 551-92-8
Purity: 99%

Basic Info

Product Name:1,2-Dimethyl-5-Nitroimidazole
Other Names:Dimetridazole, 97%
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Organic Intermediate
Appearance:White to Yellow With a Green Cast Crystalline Powder
EINECS No.:209-001-2
Storage:Inert Atmosphere,2-8°C
Provide:1,2-Dimethyl-5-Nitroimidazole MSDS;
SigmaAldrich COA

What is 1,2-Dimethyl-5-Nitroimidazole?

Dimetridazole, also known as dimezole, this product is off-white or slightly yellow powder, odorless, bitter in taste, gradually turns black when exposed to light, easily soluble in chloroform and ethanol, slightly soluble in water or ether.

1,2-Dimethyl-5-Nitroimidazole Properties:

Melting point 177-182°C
Boiling point 258.15°C (rough estimate)
density 1.3818 (rough estimate)
refractive index 1.6190 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility ethanol: soluble50mg/mL
form Crystalline Powder
color white to yellow with a green cast
Water Solubility 9.69g/L(20 ºC)


1,2-Dimethyl-5-Nitroimidazole Uses

  1. Dimetronidazole is mainly used as a veterinary antibacterial drug, and is the first choice for the prevention and treatment of swine dysentery. It can also be used as a feed additive to promote the growth of livestock and poultry, and a small amount is used in daily chemicals.
  2. Dimetronidazole is a growth-promoting agent for livestock and poultry and a broad-spectrum antiprotozoal drug with high efficiency and low toxicity. It can be used for pig feed, the dosage is 50-100g/t; it can also be used for chicken feed, the dosage is 125-200g/t.
  3. Dimetronidazole is a high-efficiency, low-toxicity, broad-spectrum antibacterial and antiprotozoal treatment or preventive drug.
  4. Dimetronidazole is a broad-spectrum anti-anaerobic bacteria and antiprotozoal drug.

Production Method of Dimethylnidazole

Using 2-methylimidazole as resources, it is obtained by nitration and methyl esterification. Dissolve 40 g of urea in 100 mL of water, and also add 40 mL of focused nitric acid to obtain remedy I. Managing the temperature level to be less than 50 ° C, slowly adding 70 g of 2-methylimidazole to 200 mL of industrial sulfuric acid to get service II. The option II was slowly poured into the remedy I, positioned at area temperature level for 24 hr, then heated up to 80 ° C with stirring for 2 hrs, and also heated up to 110 ° C for 0.5 hours. After cooling to 80 ° C, 200 mL of focused nitric acid was included dropwise, the temperature was raised to 120 ° C, and also the response was mixed for 2 h. Ultimately, the excess nitric acid was evaporated below 150 ° C. Cool to 40 ℃, dilute with 400mL water, adjust pH=3.5-4.0 with ammonia water. It was cooled to area temperature, filteringed system, cleaned with water as well as additionally dried to get 83.8 g of 2-methyl-5-nitroimidazole (melting point 248-250 ° C )with a yield of 77.3%.Add 50 g of the above item and 60 mL of 85% formic acid to the three-necked flask, heat to 80 ° C, dropwise include 60 g of dimethyl sulfate [( CH3)2SO4] within 30 minutes, and after that respond for 0.5 h. Then vaporize the solvent, include 50 mL of water, distill the recurring acid, consist of 50 mL of water, as well as adjust the pH=2.5 with ammonia water. Fantastic to location temperature level, filter, as well as additionally completely dry the filter residue to get 12.4 g of unreacted 2-methyl-5-nitroimidazole. After the filtrate was decolorized with activated carbon, ammonia water was contributed to readjust the pH to 6-7, filteringed system, cleaned and dried to obtain 29.3 g of the product (melting point 138-140 ° C) with a return of 70.3%. The total yield was 54.3%.

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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