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γ-Cyclodextrin CAS 17465-86-0

Molecular Formula: C48H80O40

Formula Weight: 1297.12

ZSpharmac: γ-Cyclodextrin Cosmetic Raw Material Suppliers

Product Name: γ-Cyclodextrin
CAS No: 17465-86-0
Purity: 99%

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Basic Info

Product Name:γ-Cyclodextrin
Other Names:Cyclooctapentylose
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:241-482-4
Storage:Room Temp
Provide:γ-Cyclodextrin MSDS;
γ-Cyclodextrin COA

What is γ-Cyclodextrin?

γ-cyclodextrin (γ-CD) is developed by cyclodextrin glycosyltransferase acting on glucose polymers such as starch, glycogen, malt, and oligosaccharides. It consists of 8 D-glucopyranosyl groups. A cyclic oligosaccharide linked head to tail by α-1,4-glycosidic bonds has a distinct barrel structure with hydrophilic exterior and also hydrophobic interior, which can be used to solubilize as well as stabilize visitor particles. Presently, γ-CD is primarily utilized as basic material for the manufacturing of sugammadex sodium. Sugammadex sodium is usually used as a shot as a muscle relaxant for neuromuscular clog. It can cause allergic reactions as well as hypersensitivity responses in individuals, as well as the allergic reactions are caused by macromolecular exogenous healthy proteins. γ-Cyclodextrin is mainly gotten by chemical hydrolysis of starch by cyclodextrin glycosyltransferase (CGTase, EC2.4.1.19).

γ-Cyclodextrin Property

Melting point ≥300 °C
Boiling point 845.2°C (rough estimate)
alpha [α]D25 +174~+179° (c=1, H2O) (After Drying)
density 1.2064 (rough estimate)
refractive index 1.7500 (estimate)
Fp 450℃
storage temp. room temp
solubility 1 M NaOH: 25 mg/mL, may be clear to slightly hazy
form powder
color white
Odorat 100.00?%. odorless
optical activity[α]/D 174.0 to 180.0°
Water Solubility 232g/L(25 ºC)


γ-Cyclodextrin Uses

γ-Cyclodextrin has an opening in the center of the ring structure. There are -CH- oxygen atoms followed glucoside within, which is sulfur water. The -OH teams at placements 2, 3 and also 6 of glucose are hydrophilic along with can take a trip via Weak van der Waals pressures made complex other particles right into additions. There are a number of materials that can be consisted of by cyclodextrin, including uncommon gases, halogens, dyes, spices, medications, food, chemicals and also chemicals. After encapsulation, its safety, volatility, solubility and also sensitivity are boosted. This unique feature of cyclodextrin makes it a covering item with huge application worth.

1. Usage in pharmaceutical sector
γ-Cyclodextrin can be made use of to develop consolidations (encapsulation) with medicines, which can maintain (1) unsteady medicines; (2) deliquescent, glue or fluid drugs right into powder; (3) inadequately soluble or insoluble medicines Medicine solubilization (solubilization), and so on

2. Use in chemical market
γ-Cyclodextrin is consisted of as well as maintained, guaranteeing pesticides immune to storage space and likewise boosting insecticidal performance.

3. Usage in food market
γ-Cyclodextrin is made use of in the food market and also has the abiding by features: (1) elimination in addition to masking of particular odors; (2) remodelling along with renovation of food cells framework; (3) decrease as well as likewise removal of bitter taste; (4) antioxidant Function; (5) Maintenance along with optimization of flavor.

4. Use in day-to-day chemical industry
Cyclodextrin can also be used as an emulsifier and excellent quality improver in cosmetics making. It furthermore has deodorising (such as halitosis) along with disinfectant outcomes, and also can be made use of in the manufacture of tooth paste and tooth powder.

5. Other uses
It can be taken advantage of as a therapy agent for oily sewer in environmental management. The liquid solution of cyclodextrin is used to clean up the oil tank, in addition to the waste fluid can be recycled in addition to processed to obtain gas oil.

6.Uses of γ-Cyclodextrin in the field of chemistry
Cyclodextrin is a valuable chemical reagent. When it is present, the fluorescence intensity of fluorescent dyes will increase significantly, so it can be used for the analysis of proteins and amino acids; it can also be used to separate long-chain organic compounds, racemates, etc. In addition, adsorbents made of cyclodextrin can be used for adsorption in chromatographic analysis. This reaction can also be carried out in benzene (or acetonitrile). Although potassium cyanide is insoluble in benzene, if 18-crown-6 is added, not only can the reaction occur, but the yield can be as high as 95%. Toxicity of 18-crown-6: The oral lethal dose in rats is 300 mg/kg. Irritating to eyes and skin.

γ-Cyclodextrin Content Analysis

Recognize according to fluid chromatography method in GT-10. The size of the column used is 30cm, the interior dimension is 7.8 mm, and also it contains Aminex HPX-42A (Bio-RadLaboratoties) or similar products, with a bit size of 25/ μm. The solvent is water. The blood circulation price is 0.3 ~ 1.0 ml/min. Temperature degree 65 ℃, ± 10 ℃. The shot volume is 20 ~ 100/ μ1. The detector is a differential refractometer.
Test liquid: Take 1.0 g of the sample as well as additionally liquify it in 100ml of water.
Compute the material of γ-cyclodextrin/%= peak location of γ-cyclodextrin/ sum of the tape-recorded top areas × 100%.

γ-Cyclodextrin Production Methods

Cyclic maltodextrin glucose transferase (CGTase, EC2.4.1.19) acts on the hydrolyzed starch, and after that detoxifies using one of the complying with techniques: cyclodextrin is precipitated with a complicated of a macrocyclic compound, and then Essence with n-decane, and then strip the solvent; acquire crystals from the purified mommy liquor consisting of cyclodextrin by ion exchange or gel filtration chromatographic separation; get by membrane splitting up of ultrafiltration and also turn around osmosis.

About Products:
If you need γ-Cyclodextrin, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced γ-Cyclodextrin manufacturer and supplier, our company, ZSpharmac will provide γ-Cyclodextrin raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get γ-Cyclodextrin Quotation