Creatine monohydrate (CAS No.: 6020-87-7), is a kind of medicine raw material and health care product additive. It can inhibit the generation of muscle fatigue factors, reduce fatigue and tension, restore physical fitness, accelerate the body’s protein synthesis, make muscles stronger, enhance muscle elasticity, reduce cholesterol, blood lipids, and blood sugar levels, improve middle-aged and elderly muscular dystrophy, and delay aging.
Creatine monohydrate is known as one of the most popular and effective nutritional supplements, and its status is high enough to keep pace with protein products and ranks firmly among the “best selling supplements”. It is rated as a “must use” product for bodybuilders, and it is also widely used by athletes in other sports, such as football and basketball players, who want to improve their energy level and strength. Creatine is not a banned drug. It is naturally present in many foods. Therefore, creatine should not be banned in any sports organization.
The literature shows that creatine monohydrate can reduce the oxidation and decomposition of leucine, increase its availability and muscle retention (or possible growth). Creatine monohydrate has been shown to be associated with increased performance (activity) of the anabolic hormone insulin-like growth factor (IGF-1), thereby further helping muscle maintenance.
Food additives, cosmetic surfactants, feed additives, beverage additives, pharmaceutical raw materials and health care products additives can also be directly made into capsules and tablets for oral administration.
According to a small sample study in Japan, creatine monohydrate can improve the muscle function of patients with mitochondrial diseases, but the degree of improvement varies among individuals, which is related to the biochemical and genetic characteristics of the muscle fibers of the patients.